Rank	Pathway_ID	Pathway_Name	Total_Gene_Number	Pathway_Class_1st	Pathway_Class_2nd	Gene_Names	Gene_IDs	Num_Targets	P_value_target	P_value_drug
1	hsa05216	Thyroid cancer	37	Human Diseases	Cancers: Specific types	PPARG;RXRA	5468;6256	2	0.0014993487462376096	0.3554787040419351
2	hsa03320	PPAR signaling pathway	74	Organismal Systems	Endocrine system	PPARG;RXRA	5468;6256	2	0.0030302723870285655	0.26374226428918895
3	hsa04919	Thyroid hormone signaling pathway	116	Organismal Systems	Endocrine system	NCOA2;RXRA	10499;6256	2	0.004969923592981521	0.10065526028424637
4	hsa05202	Transcriptional misregulation in cancer	186	Human Diseases	Cancers: Overview	PPARG;RXRA	5468;6256	2	0.009554090905374804	0.11626319621440517
5	hsa05200	Pathways in cancer	526	Human Diseases	Cancers: Overview	PPARG;RXRA	5468;6256	2	0.05944658070962126	0.25027302511927957
6	hsa05226	Gastric cancer	149	Human Diseases	Cancers: Specific types	RXRA	6256	1	0.06843830745782199	0.0957836356242329
7	hsa04932	Non-alcoholic fatty liver disease (NAFLD)	149	Human Diseases	Endocrine and metabolic diseases	RXRA	6256	1	0.06843830745782199	0.1320834850144418
8	hsa04915	Estrogen signaling pathway	137	Organismal Systems	Endocrine system	NCOA2	10499	1	0.070906865819982	0.1305634855253375
9	hsa05160	Hepatitis C	131	Human Diseases	Infectious diseases: Viral	RXRA	6256	1	0.070906865819982	0.10218420094685794
10	hsa04380	Osteoclast differentiation	128	Organismal Systems	Development	PPARG	5468	1	0.07238002108137348	0.0957836356242329
11	hsa04659	Th17 cell differentiation	107	Organismal Systems	Immune system	RXRA	6256	1	0.07413855573388649	0.10265744448520746
12	hsa04928	Parathyroid hormone synthesis, secretion and action	106	Organismal Systems	Endocrine system	RXRA	6256	1	0.07413855573388649	0.12843101565385648
13	hsa04920	Adipocytokine signaling pathway	69	Organismal Systems	Endocrine system	RXRA	6256	1	0.07415006417197705	0.17047688387385357
14	hsa04976	Bile secretion	71	Organismal Systems	Digestive system	RXRA	6256	1	0.07415006417197705	0.1419048052425547
15	hsa04152	AMPK signaling pathway	120	Environmental Information Processing	Signal transduction	PPARG	5468	1	0.07580468536366103	0.10908403573167548
16	hsa05222	Small cell lung cancer	93	Human Diseases	Cancers: Specific types	RXRA	6256	1	0.07747154532469955	0.09818665817293581
17	hsa04211	Longevity regulating pathway	89	Organismal Systems	Aging	PPARG	5468	1	0.07747154532469955	0.1560793593015206
18	hsa05223	Non-small cell lung cancer	66	Human Diseases	Cancers: Specific types	RXRA	6256	1	0.08237793024004161	0.20354022570141359
19	hsa05016	Huntington disease	193	Human Diseases	Neurodegenerative diseases	PPARG	5468	1	0.08348553760250942	0.1560793593015206
20	hsa04714	Thermogenesis	229	Organismal Systems	Environmental adaptation	PPARG	5468	1	0.09364833381478162	0.12301022603215422
21	hsa04151	PI3K-Akt signaling pathway	354	Environmental Information Processing	Signal transduction	RXRA	6256	1	0.1355550647077098	0.1760192937757532