Uniprot_ID	Protein_Name	Entry_Name	Tot_Num_Drugs	Gene_Name	Gene_ID	PDB	Pathways_ID	Pathways_Name	GO_Function	GO_Process	GO_Component	Confidence_Score	PDB_dt
P35348	Alpha-1A adrenergic receptor	ADA1A_HUMAN	113	ADRA1A	148	NA	hsa04020|hsa04022|hsa04080|hsa04152|hsa04261|hsa04270|hsa04970	Calcium signaling pathway|cGMP-PKG signaling pathway|Neuroactive ligand-receptor interaction|AMPK signaling pathway|Adrenergic signaling in cardiomyocytes|Vascular smooth muscle contraction|Salivary secretion	alpha1-adrenergic receptor activity|protein heterodimerization activity	positive regulation of action potential|signal transduction|negative regulation of cell proliferation|positive regulation of ERK1 and ERK2 cascade|G-protein coupled receptor signaling pathway|aging|response to drug|positive regulation of smooth muscle contraction|response to hormone|smooth muscle contraction|positive regulation of MAPK cascade|intracellular signal transduction|positive regulation of protein kinase C signaling|cell-cell signaling|adenylate cyclase-activating adrenergic receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of synaptic transmission, GABAergic|norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure|calcium ion transport into cytosol|positive regulation of cytosolic calcium ion concentration|activation of phospholipase C activity|negative regulation of Rho protein signal transduction|positive regulation of vasoconstriction|positive regulation of cardiac muscle contraction|apoptotic process	nucleus|plasma membrane|cytosol|nuclear membrane|integral component of plasma membrane	1	NA
P18089	Alpha-2B adrenergic receptor	ADA2B_HUMAN	75	ADRA2B	151	2CVA	hsa04022|hsa04080	cGMP-PKG signaling pathway|Neuroactive ligand-receptor interaction	alpha2-adrenergic receptor activity|epinephrine binding	blood coagulation|activation of MAPK activity by adrenergic receptor signaling pathway|activation of protein kinase B activity|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|cell-cell signaling|negative regulation of epinephrine secretion|platelet activation|regulation of smooth muscle contraction|regulation of vasoconstriction|G-protein coupled receptor signaling pathway|negative regulation of norepinephrine secretion|positive regulation of neuron differentiation	plasma membrane|integral component of plasma membrane	1	NA
P08913	Alpha-2A adrenergic receptor	ADA2A_HUMAN	96	ADRA2A	150	1HLL;1HO9;1HOD;1HOF	hsa04022|hsa04080	cGMP-PKG signaling pathway|Neuroactive ligand-receptor interaction	protein homodimerization activity|thioesterase binding|protein heterodimerization activity|alpha-1B adrenergic receptor binding|alpha-2C adrenergic receptor binding|alpha2-adrenergic receptor activity|heterotrimeric G-protein binding|epinephrine binding|norepinephrine binding|protein kinase binding	regulation of insulin secretion|positive regulation of cytokine production|thermoception|acute inflammatory response|activation of protein kinase B activity|positive regulation of cell proliferation|activation of protein kinase activity|signal transduction|negative regulation of insulin secretion|adenylate cyclase-inhibiting adrenergic receptor signaling pathway|glucose homeostasis|blood coagulation|negative regulation of lipid catabolic process|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|actin cytoskeleton organization|Rho protein signal transduction|DNA replication|positive regulation of epidermal growth factor-activated receptor activity|negative regulation of epinephrine secretion|cellular response to hormone stimulus|positive regulation of potassium ion transport|negative regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of cell migration|negative regulation of norepinephrine secretion|negative regulation of adrenergic receptor signaling pathway|Ras protein signal transduction|negative regulation of uterine smooth muscle contraction|female pregnancy|negative regulation of calcium ion transmembrane transporter activity|negative regulation of cAMP biosynthetic process|cell-cell signaling|negative regulation of calcium ion-dependent exocytosis|fear response|positive regulation of wound healing|movement of cell or subcellular component|platelet activation|phospholipase C-activating adrenergic receptor signaling pathway|negative regulation of calcium ion transport|energy reserve metabolic process|intestinal absorption|negative regulation of adenylate cyclase activity|regulation of vasoconstriction|positive regulation of vasodilation|G-protein coupled receptor signaling pathway|positive regulation of membrane protein ectodomain proteolysis|positive regulation of MAP kinase activity|small molecule metabolic process|activation of MAPK activity by adrenergic receptor signaling pathway	cytoplasm|integral component of plasma membrane|plasma membrane|receptor complex|basolateral plasma membrane|synapse	1	NA