Rank	Pathway_ID	Pathway_Name	Total_Gene_Number	Pathway_Class_1st	Pathway_Class_2nd	Gene_Names	Gene_IDs	Num_Targets	P_value_target	P_value_drug
1	hsa04022	cGMP-PKG signaling pathway	163	Environmental Information Processing	Signal transduction	ADRA2A;ADRA2B;ADRA1A	150;151;148	3	7.142317702728112e-05	0.16385147433615196
2	hsa04080	Neuroactive ligand-receptor interaction	277	Environmental Information Processing	Signaling molecules and interaction	ADRA2A;ADRA2B;ADRA1A	150;151;148	3	0.0001766046843266552	0.2715689843480953
3	hsa04270	Vascular smooth muscle contraction	121	Organismal Systems	Circulatory system	ADRA1A	148	1	0.06618630192530064	0.1755096468880693
4	hsa04261	Adrenergic signaling in cardiomyocytes	144	Organismal Systems	Circulatory system	ADRA1A	148	1	0.06618630192530064	0.16385147433615196
5	hsa04152	AMPK signaling pathway	120	Environmental Information Processing	Signal transduction	ADRA1A	148	1	0.06694490228825684	0.28030578813352136
6	hsa04020	Calcium signaling pathway	183	Environmental Information Processing	Signal transduction	ADRA1A	148	1	0.07171758805617232	0.21171581118860047
7	hsa04970	Salivary secretion	90	Organismal Systems	Digestive system	ADRA1A	148	1	0.08300071999042365	0.18941875985980539