QuartataWeb 1.0

6 known interactions (targets) of input drug (DB00975): Dipyridamole

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	ORM1	P02763	Alpha-1-acid glycoprotein 1	NA	3KQ0
2	PDE5A	O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	hsa00230; hsa04022	1RKP; 1T9R; 1T9S; 1TBF; 1UDT; 1UDU; 1UHO; 1XOZ; 1XP0; 2CHM; 2H40; 2H42; 2H44; 2XSS; 3B2R; 3BJC; 3HC8; 3HDZ; 3JWQ; 3JWR; 3LFV; 3MF0; 3SHY; 3SHZ; 3SIE; 3TGE; 3TGG; 4G2W; 4G2Y; 4I9Z; 4IA0; 4MD6; 4OEW; 4OEX
3	ADA	P00813	Adenosine deaminase	hsa00230; hsa01100; hsa05340	1M7M; 3IAR
4	RCAN1	P53805	Calcipressin-1	hsa04919; hsa04921; hsa05167	NA
5	PDE10A	Q9Y233	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	hsa00230; hsa05032	1LRB; 2OUN; 2OUP; 2OUQ; 2OUR; 2OUS; 2OUU; 2OUV; 2OUY; 2WEY; 2Y0J; 2ZMF; 3SN7; 3SNI; 3SNL; 3UI7; 3UUO; 3WI2; 3WS8; 3WS9; 3WYK; 3WYL; 3WYM; 4AEL; 4AJD; 4AJF; 4AJG; 4AJM; 4BBX; 4DDL; 4DFF; 4FCB; 4FCD; 4HEU; 4HF4; 4LKQ; 4LLJ; 4LLK; 4LLP; 4LLX; 4LM0; 4LM1; 4LM2; 4LM3; 4LM4; 4MRW; 4MRZ; 4MS0; 4MSA; 4MSC; 4MSE; 4MSH; 4MSN; 4MUW; 4MVH; 4P0N; 4P1R; 4PHW; 4TPM; 4TPP; 4WN1; 4XY2; 4YQH; 4YS7; 4ZO5; 5AXP; 5AXQ; 5C1W; 5C28; 5C29; 5C2A; 5C2H
6	PDE4A	P27815	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	hsa00230; hsa04024; hsa04928; hsa05032	2QYK; 3I8V; 3TVX

20 predicted interactions (targets) of input drug (DB00975): Dipyridamole

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	PDE4B	Q07343	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	hsa00230; hsa04024; hsa04928; hsa05032	1F0J; 1JP1; 1JP2; 1RO6; 1RO9; 1ROR; 1TB5; 1XLX; 1XLZ; 1XM4; 1XM6; 1XMU; 1XMY; 1XN0; 1XOS; 1XOT; 1Y2H; 1Y2J; 2CHM; 2QYL; 3D3P; 3FRG; 3G45; 3GWT; 3HC8; 3HDZ; 3HMV; 3KKT; 3LY2; 3O0J; 3O56; 3O57; 3W5E; 3WD9; 4KP6; 4MYQ; 4NW7; 4WZI; 4X0F	47.6%
2	PDE4D	Q08499	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	hsa00230; hsa04024; hsa04928; hsa05032	1E9K; 1MKD; 1OYN; 1PTW; 1Q9M; 1TB7; 1TBB; 1XOM; 1XON; 1XOQ; 1XOR; 1Y2B; 1Y2C; 1Y2D; 1Y2E; 1Y2K; 1ZKN; 2FM0; 2FM5; 2PW3; 2QYN; 3G4G; 3G4I; 3G4K; 3G4L; 3G58; 3IAD; 3IAK; 3K4S; 3SL3; 3SL4; 3SL5; 3SL6; 3SL8; 3V9B; 4OGB; 4W1O; 4WCU	41.0%
3	PDE4C	Q08493	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	hsa00230; hsa04024; hsa04928; hsa05032	1LXU; 2QYM	40.3%
4	PDE2A	O00408	cGMP-dependent 3',5'-cyclic phosphodiesterase	hsa00230; hsa04022; hsa04740; hsa04925; hsa05032	1Z1L; 3IBJ; 3ITM; 3ITU; 4C1I; 4D08; 4D09; 4HTX; 4HTZ; 4JIB	29.6%
5	PDE3A	Q14432	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	hsa00230; hsa04022; hsa04024; hsa04924; hsa05032	1LRC	29.5%
6	PDE8A	O60658	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	hsa00230; hsa04927; hsa04934; hsa05032	1LHQ; 1LXX; 3ECM; 3ECN	28.9%
7	OPRM1	P35372	Mu-type opioid receptor	hsa04080; hsa04915; hsa05032	NA	28.4%
8	TOP2A	P11388	DNA topoisomerase 2-alpha	hsa01524	1LWZ; 1ZXM; 1ZXN; 4FM9; 4R1F	24.8%
9	PDE9A	O76083	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	hsa00230	2HD1; 2YY2; 3DY8; 3DYL; 3DYN; 3DYQ; 3DYS; 3JSI; 3JSW; 3K3E; 3K3H; 3N3Z; 3QI3; 3QI4; 4E90; 4G2J; 4G2L; 4GH6; 4Y86; 4Y87; 4Y8C	22.9%
10	ADORA2A	P29274	Adenosine receptor A2a	hsa04015; hsa04020; hsa04024; hsa04080; hsa04270; hsa05012; hsa05034	1MMH; 1UPE; 2YDO; 2YDV; 3EML; 3PWH; 3QAK; 3REY; 3RFM; 3UZA; 3UZC; 3VG9; 3VGA; 4EIY; 4UG2; 4UHR	22.7%
11	PDE8B	O95263	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	hsa00230; hsa04927; hsa04934; hsa05032	NA	22.7%
12	PIM1	P11309	Serine/threonine-protein kinase pim-1	hsa04630; hsa04933; hsa05200; hsa05206; hsa05221	1XQZ; 1XR1; 1XWS; 1YHS; 1YI3; 1YI4; 1YWV; 1YXS; 1YXT; 1YXU; 1YXV; 1YXX; 2BIK; 2BIL; 2BZH; 2BZI; 2BZJ; 2BZK; 2C3I; 2J2I; 2O3P; 2O63; 2O64; 2O65; 2OBJ; 2OI4; 2XIX; 2XIY; 2XIZ; 2XJ0; 2XJ1; 2XJ2; 3A99; 3BGP; 3BGQ; 3BGZ; 3BWF; 3C4E; 3CXW; 3CY2; 3CY3; 3DCV; 3F2A; 3JPV; 3JXW; 3JY0; 3JYA; 3MA3; 3QF9; 3R00; 3R01; 3R02; 3R04; 3T9I; 3UIX; 3UMW; 3UMX; 3VBQ; 3VBT; 3VBV; 3VBW; 3VBX; 3VBY; 3VC4; 3WE8; 4A7C; 4ALU; 4ALV; 4ALW; 4AS0; 4BZN; 4BZO; 4DTK; 4ENX; 4ENY; 4GW8; 4I41; 4IAA; 4JX3; 4JX7; 4K0Y; 4K18; 4K1B; 4LL5; 4LM5; 4LMU; 4MBI; 4MBL; 4MED; 4MTA; 4N6Y; 4N6Z; 4N70; 4RBL; 4RC2; 4RC3; 4RC4; 4RPV; 4TY1; 4WRS; 4WSY; 4WT6; 4XH6; 4XHK; 5DGZ; 5DHJ; 5DIA; 5DWR	22.5%
13	PDE3B	Q13370	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	hsa00230; hsa04022; hsa04024; hsa04371; hsa04910; hsa04914; hsa04922; hsa04923; hsa04924; hsa05032	1SO2; 1SOJ	22.0%
14	PDE7A	Q13946	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	hsa00230; hsa05032	1ZKL; 3G3N; 4PM0; 4Y2B	21.8%
15	NQO1	P15559	NAD(P)H dehydrogenase [quinone] 1	hsa00130; hsa05200; hsa05225; hsa05418	1D4A; 1DXO; 1GG5; 1H66; 1H69; 1KBO; 1KBQ; 1QBG; 2F1O; 3JSX; 4CET; 4CF6	21.6%
16	ORM2	P19652	Alpha-1-acid glycoprotein 2	NA	3APU; 3APV; 3APW; 3APX	21.5%
17	F10	P00742	Coagulation factor X	hsa04610	1C5M; 1EZQ; 1F0R; 1F0S; 1FAX; 1FJS; 1FXY; 1G2L; 1G2M; 1HCG; 1IOE; 1IQE; 1IQF; 1IQG; 1IQH; 1IQI; 1IQJ; 1IQK; 1IQL; 1IQM; 1IQN; 1KSN; 1LPG; 1LPK; 1LPZ; 1LQD; 1MQ5; 1MQ6; 1MSX; 1NFU; 1NFW; 1NFX; 1NFY; 1NL8; 1P0S; 1V3X; 1WU1; 1XKA; 1XKB; 1Z6E; 2BMG; 2BOH; 2BOK; 2BQ6; 2BQ7; 2BQW; 2CJI; 2D1J; 2EI6; 2EI7; 2EI8; 2FZZ; 2G00; 2GD4; 2H9E; 2J2U; 2J34; 2J38; 2J4I; 2J94; 2J95; 2JKH; 2P16; 2P3F; 2P3T; 2P3U; 2P93; 2P94; 2P95; 2PHB; 2PR3; 2Q1J; 2RA0; 2UWL; 2UWO; 2UWP; 2VH0; 2VH6; 2VVC; 2VVU; 2VVV; 2VWL; 2VWM; 2VWN; 2VWO; 2W26; 2W3I; 2W3K; 2WYG; 2WYJ; 2XBV; 2XBW; 2XBX; 2XBY; 2XC0; 2XC4; 2XC5; 2Y5F; 2Y5G; 2Y5H; 2Y7X; 2Y7Z; 2Y80; 2Y81; 2Y82; 3CEN; 3CS7; 3ENS; 3FFG; 3HPT; 3IIT; 3K9X; 3KL6; 3KQB; 3KQC; 3KQD; 3KQE; 3LIW; 3M36; 3M37; 3Q3K; 3SW2; 3TK5; 3TK6; 4A7I; 4BTI; 4BTT; 4BTU; 4Y6D; 4Y71; 4Y76; 4Y79; 4Y7A; 4Y7B	21.4%
18	PDE7B	Q9NP56	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	hsa00230; hsa05032	1LXW	21.4%
19	NR3C1	P04150	Glucocorticoid receptor	hsa04080	1M2Z; 1NHZ; 1P93; 3BQD; 3CLD; 3E7C; 3H52; 3K22; 3K23; 4CSJ; 4HN5; 4HN6; 4LSJ; 4MDD; 4P6W; 4P6X	21.3%
20	PDE11A	Q9HCR9	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	hsa00230; hsa04934; hsa05032	NA	21.3%