QuartataWeb 1.0

Data source: DrugBank-all; Query type: chemical; # of requested predictions: 20; Secondary interactions: no
Input drug 1: DB02573

No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter Image

1 Experimental SmallMoleculeDrug DB02573 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate
[H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(=O)O[C@@]1([H])C[C@@]([H])(O[C@]1([H])CO)N1C=CC(=N)N=C1O)N1C=NC2=C(N)N=CN=C12

1 known interactions (targets) of input drug (DB02573): 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	RNASE1	P07998	Ribonuclease pancreatic	NA	1DZA; 1E21; 1H8X; 1Z7X; 2E0J; 2E0L; 2E0M; 2E0O; 2K11; 2Q4G; 3F8G; 4KXH

17 predicted interactions (targets) of input drug (DB02573): 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	PPARG	P37231	Peroxisome proliferator-activated receptor gamma	hsa03320; hsa04152; hsa04211; hsa04380; hsa04714; hsa05016; hsa05200; hsa05202; hsa05216	1FM6; 1FM9; 1I7I; 1K74; 1KNU; 1NYX; 1PRG; 1RDT; 1WM0; 1ZEO; 1ZGY; 2ATH; 2F4B; 2FVJ; 2G0G; 2G0H; 2GTK; 2HFP; 2HWQ; 2HWR; 2I4J; 2I4P; 2I4Z; 2OM9; 2P4Y; 2POB; 2PRG; 2Q59; 2Q5P; 2Q5S; 2Q61; 2Q6R; 2Q6S; 2Q8S; 2QMV; 2VSR; 2VST; 2VV0; 2VV1; 2VV2; 2VV3; 2VV4; 2XKW; 2YFE; 2ZK0; 2ZK1; 2ZK2; 2ZK3; 2ZK4; 2ZK5; 2ZK6; 2ZNO; 2ZVT; 3ADS; 3ADT; 3ADU; 3ADV; 3ADW; 3ADX; 3AN3; 3AN4; 3B0Q; 3B0R; 3B1M; 3B3K; 3BC5; 3CDP; 3CDS; 3CS8; 3CWD; 3D6D; 3DZU; 3DZY; 3E00; 3ET0; 3ET3; 3FEJ; 3FUR; 3G9E; 3GBK; 3H0A; 3HO0; 3HOD; 3IA6; 3K8S; 3KMG; 3LMP; 3NOA; 3OSI; 3OSW; 3PBA; 3PO9; 3PRG; 3QT0; 3R5N; 3R8A; 3R8I; 3S9S; 3SZ1; 3T03; 3TY0; 3U9Q; 3V9T; 3V9V; 3V9Y; 3VJH; 3VJI; 3VN2; 3VSO; 3VSP; 3WJ4; 3WJ5; 3WMH; 3X1H; 3X1I; 4A4V; 4A4W; 4CI5; 4E4K; 4E4Q; 4EM9; 4EMA; 4F9M; 4FGY; 4HEE; 4JAZ; 4JL4; 4L96; 4L98; 4O8F; 4OJ4; 4PRG; 4PVU; 4PWL; 4R2U; 4R6S; 4XLD; 4XTA; 4XUM; 4Y29	19.3%
2	PRSS1	P07477	Trypsin-1	hsa04080; hsa04972; hsa04974; hsa05164	1FXY; 1TRN; 2RA3; 4WWY; 4WXV	13.7%
3	ATIC	P31939	Bifunctional purine biosynthesis protein PURH	hsa00230; hsa00670; hsa01100; hsa01523	1P4R; 1PKX; 1PL0	12.7%
4	TOP1	P11387	DNA topoisomerase 1	NA	1A31; 1A35; 1A36; 1EJ9; 1K4S; 1K4T; 1LPQ; 1NH3; 1R49; 1RR8; 1RRJ; 1SC7; 1SEU; 1T8I; 1TL8	12.5%
5	DLG4	P78352	Disks large homolog 4	hsa04390; hsa04724; hsa05016; hsa05030	1KEF; 2MES; 3I4W; 3K82; 3ZRT	11.9%
6	LSM6	P62312	U6 snRNA-associated Sm-like protein LSm6	hsa03018; hsa03040	NA	11.8%
7	CAD	P27708	CAD protein	hsa00240; hsa00250; hsa01100	4BY3; 4C6B; 4C6C; 4C6D; 4C6E; 4C6F; 4C6I; 4C6J; 4C6K; 4C6L; 4C6M; 4C6N; 4C6O; 4C6P; 4C6Q	11.7%
8	RNASE4	P34096	Ribonuclease 4	NA	1RNF; 2RNF	11.3%
9	IFNAR1	P17181	Interferon alpha/beta receptor 1	hsa04060; hsa04151; hsa04217; hsa04380; hsa04620; hsa04621; hsa04630; hsa04650; hsa05160; hsa05161; hsa05162; hsa05164; hsa05165; hsa05167; hsa05168; hsa05200	3S98; 3SE3; 3SE4; 4PO6	11.1%
10	TRPM7	Q96QT4	Transient receptor potential cation channel subfamily M member 7	hsa04217; hsa04218; hsa04621; hsa04978	NA	10.8%
11	GPI	P06744	Glucose-6-phosphate isomerase	hsa00010; hsa00030; hsa00500; hsa00520; hsa01100; hsa01200	1IAT; 1IRI; 1JIQ; 1JLH; 1NUH	10.8%
12	COMT	P21964	Catechol O-methyltransferase	hsa00140; hsa00350; hsa01100; hsa04728	3A7E; 3BWM; 3BWY; 4PYI; 4PYJ; 4PYK; 4XUC; 4XUD; 4XUE	10.7%
13	RNASE3	P12724	Eosinophil cationic protein	hsa05310	1DYT; 1H1H; 1QMT; 2KB5; 2LVZ; 4A2O; 4A2Y; 4OWZ; 4OXB; 4OXF; 4X08	10.6%
14	PAH	P00439	Phenylalanine-4-hydroxylase	hsa00360; hsa00400; hsa00790; hsa01100; hsa01230	1DMW; 1J8T; 1J8U; 1KW0; 1LRM; 1MMK; 1MMT; 1PAH; 1TDW; 1TG2; 2PAH; 3PAH; 4ANP; 4PAH; 5PAH; 6PAH	10.5%
15	UQCR11	O14957	Cytochrome b-c1 complex subunit 10	hsa00190; hsa01100; hsa04260; hsa04714; hsa04932; hsa05010; hsa05012; hsa05016	NA	10.4%
16	ABCC8	Q09428	ATP-binding cassette sub-family C member 8	hsa02010; hsa04911; hsa04930	NA	10.4%
17	GSTA3	Q16772	Glutathione S-transferase A3	hsa00480; hsa00980; hsa00982; hsa00983; hsa01524; hsa05200; hsa05204; hsa05225; hsa05418	1TDI; 2VCV	10.2%