QuartataWeb 1.0

4 known interactions (targets) of input drug (DB04493): Fructose-6-Phosphate

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PFKFB4	Q16877	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4	hsa00051; hsa04152	NA
2	GPI	P06744	Glucose-6-phosphate isomerase	hsa00010; hsa00030; hsa00500; hsa00520; hsa01100; hsa01200	1IAT; 1IRI; 1JIQ; 1JLH; 1NUH
3	FBP1	P09467	Fructose-1,6-bisphosphatase 1	hsa00010; hsa00030; hsa00051; hsa01100; hsa01200; hsa04152; hsa04910; hsa04922	1FTA; 2FHY; 2FIE; 2FIX; 2JJK; 2VT5; 2WBB; 2WBD; 2Y5K; 2Y5L; 3A29; 3KBZ; 3KC0; 3KC1; 4MJO
4	PFKFB1	P16118	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1	hsa00051; hsa04152; hsa04922	1K6M

20 predicted interactions (targets) of input drug (DB04493): Fructose-6-Phosphate

No.	Gene	UniProt ID	Protein Name	Pathway	PDB	Confidence score
1	F2	P00734	Prothrombin	hsa04080; hsa04610; hsa04810	1A2C; 1A3B; 1A3E; 1A46; 1A4W; 1A5G; 1A61; 1ABI; 1ABJ; 1AD8; 1AE8; 1AFE; 1AHT; 1AI8; 1AIX; 1AWF; 1AWH; 1AY6; 1B5G; 1B7X; 1BA8; 1BB0; 1BCU; 1BHX; 1BMM; 1BMN; 1BTH; 1C1U; 1C1V; 1C1W; 1C4U; 1C4V; 1C4Y; 1C5L; 1C5N; 1C5O; 1CA8; 1D3D; 1D3P; 1D3Q; 1D3T; 1D4P; 1D6W; 1D9I; 1DE7; 1DIT; 1DM4; 1DOJ; 1DWB; 1DWC; 1DWD; 1DWE; 1DX5; 1E0F; 1EB1; 1EOJ; 1EOL; 1FPC; 1FPH; 1G30; 1G32; 1G37; 1GHV; 1GHW; 1GHX; 1GHY; 1GJ4; 1GJ5; 1H8D; 1H8I; 1HAG; 1HAH; 1HAI; 1HAO; 1HAP; 1HBT; 1HDT; 1HGT; 1HLT; 1HUT; 1HXE; 1HXF; 1IHS; 1IHT; 1JMO; 1JOU; 1JWT; 1K21; 1K22; 1KTS; 1KTT; 1LHC; 1LHD; 1LHE; 1LHF; 1LHG; 1MH0; 1MU6; 1MU8; 1MUE; 1NM6; 1NO9; 1NRN; 1NRO; 1NRP; 1NRQ; 1NRR; 1NRS; 1NT1; 1NU7; 1NU9; 1NY2; 1NZQ; 1O0D; 1O2G; 1O5G; 1OOK; 1OYT; 1P8V; 1PPB; 1QBV; 1QHR; 1QJ1; 1QJ6; 1QJ7; 1QUR; 1RD3; 1RIW; 1SB1; 1SFQ; 1SG8; 1SGI; 1SHH; 1SL3; 1SR5; 1T4U; 1T4V; 1TA2; 1TA6; 1TB6; 1TBZ; 1THP; 1THR; 1THS; 1TMB; 1TMT; 1TMU; 1TOM; 1TQ0; 1TQ7; 1TWX; 1UMA; 1UVS; 1VR1; 1VZQ; 1W7G; 1WAY; 1WBG; 1XM1; 1XMN; 1YPE; 1YPG; 1YPJ; 1YPK; 1YPL; 1YPM; 1Z71; 1Z8I; 1Z8J; 1ZGI; 1ZGV; 1ZRB; 2A0Q; 2A2X; 2A45; 2AFQ; 2ANK; 2ANM; 2B5T; 2BDY; 2BVR; 2BVS; 2BVX; 2BXT; 2BXU; 2C8W; 2C8X; 2C8Y; 2C8Z; 2C90; 2C93; 2CF8; 2CF9; 2CN0; 2FEQ; 2FES; 2GDE; 2GP9; 2H9T; 2HGT; 2HNT; 2HPP; 2HPQ; 2HWL; 2JH0; 2JH5; 2JH6; 2OD3; 2PGB; 2PGQ; 2PKS; 2PW8; 2R2M; 2THF; 2UUF; 2UUJ; 2UUK; 2V3H; 2V3O; 2ZC9; 2ZDA; 2ZDV; 2ZF0; 2ZFF; 2ZFP; 2ZFQ; 2ZFR; 2ZG0; 2ZGB; 2ZGX; 2ZHE; 2ZHF; 2ZHQ; 2ZHW; 2ZI2; 2ZIQ; 2ZNK; 2ZO3; 3B23; 3B9F; 3BEF; 3BEI; 3BF6; 3BIU; 3BIV; 3BV9; 3C1K; 3C27; 3D49; 3DA9; 3DD2; 3DHK; 3DT0; 3DUX; 3E6P; 3EE0; 3EGK; 3EQ0; 3F68; 3GIC; 3GIS; 3HAT; 3HKJ; 3HTC; 3JZ1; 3JZ2; 3K65; 3LDX; 3LU9; 3NXP; 3P17; 3P6Z; 3P70; 3PMH; 3PO1; 3QDZ; 3QGN; 3QLP; 3QTO; 3QTV; 3QWC; 3QX5; 3R3G; 3RLW; 3RLY; 3RM0; 3RM2; 3RML; 3RMM; 3RMN; 3RMO; 3S7H; 3S7K; 3SHA; 3SHC; 3SI3; 3SI4; 3SQE; 3SQH; 3SV2; 3T5F; 3TU7; 3U69; 3U8O; 3U8R; 3U8T; 3U98; 3U9A; 3UTU; 3UWJ; 3VXE; 3VXF; 4AX9; 4AYV; 4AYY; 4AZ2; 4BAH; 4BAK; 4BAM; 4BAN; 4BAO; 4BAQ; 4BOH; 4CH2; 4CH8; 4DIH; 4DII; 4DT7; 4DY7; 4E05; 4E06; 4E7R; 4H6S; 4H6T; 4HFP; 4HTC; 4HZH; 4I7Y; 4LOY; 4LXB; 4LZ1; 4LZ4; 4MLF; 4N3L; 4NZE; 4NZQ; 4O03; 4RKJ; 4RKO; 4RN6; 4THN; 4UD9; 4UDW; 4UE7; 4UEH; 4YES; 5AF9; 5AFY; 5AFZ; 5AHG; 5E8E; 5GDS; 7KME; 8KME	31.0%
2	ADORA2A	P29274	Adenosine receptor A2a	hsa04015; hsa04020; hsa04024; hsa04080; hsa04270; hsa05012; hsa05034	1MMH; 1UPE; 2YDO; 2YDV; 3EML; 3PWH; 3QAK; 3REY; 3RFM; 3UZA; 3UZC; 3VG9; 3VGA; 4EIY; 4UG2; 4UHR	29.5%
3	RNASE1	P07998	Ribonuclease pancreatic	NA	1DZA; 1E21; 1H8X; 1Z7X; 2E0J; 2E0L; 2E0M; 2E0O; 2K11; 2Q4G; 3F8G; 4KXH	28.5%
4	GSK3B	P49841	Glycogen synthase kinase-3 beta	hsa01521; hsa04012; hsa04062; hsa04110; hsa04150; hsa04151; hsa04310; hsa04340; hsa04360; hsa04390; hsa04510; hsa04550; hsa04657; hsa04660; hsa04662; hsa04722; hsa04728; hsa04910; hsa04916; hsa04917; hsa04919; hsa04931; hsa04932; hsa04934; hsa05010; hsa05160; hsa05162; hsa05163; hsa05164; hsa05165; hsa05166; hsa05167; hsa05169; hsa05200; hsa05210; hsa05213; hsa05215; hsa05217; hsa05224; hsa05225; hsa05226	1GNG; 1H8F; 1I09; 1J1B; 1J1C; 1O6K; 1O6L; 1O9U; 1PYX; 1Q3D; 1Q3W; 1Q41; 1Q4L; 1Q5K; 1R0E; 1UV5; 2JDO; 2JDR; 2JLD; 2O5K; 2OW3; 2UW9; 2X39; 2XH5; 3CQU; 3CQW; 3DU8; 3E87; 3E88; 3E8D; 3F7Z; 3F88; 3GB2; 3I4B; 3L1S; 3M1S; 3MV5; 3OW4; 3PUP; 3Q3B; 3QKK; 3SAY; 3SD0; 3ZDI; 3ZRK; 3ZRL; 3ZRM; 4ACC; 4ACD; 4ACG; 4ACH; 4AFJ; 4B7T; 4DIT; 4EKK; 4IQ6; 4J1R; 4J71; 4NM0; 4NM3; 4NM5; 4NM7; 4PTC; 4PTE; 4PTG	22.7%
5	ADA	P00813	Adenosine deaminase	hsa00230; hsa01100; hsa05340	1M7M; 3IAR	22.7%
6	PKIA	P61925	cAMP-dependent protein kinase inhibitor alpha	hsa05034	1CMK; 1JLU; 1Q8T; 1VEB; 1XH4; 1XH5; 1XH6; 1XH7; 1XH8; 1XH9; 1XHA; 1YDR; 2C1A; 2C1B; 2F7E; 2GNI; 2JDS; 2JDT; 2JDV; 2L1L; 2UVX; 2UVY; 2UVZ; 2UW0; 2UW3; 2UW4; 2UW5; 2UW6; 2UW7; 2UW8; 2VNW; 2VNY; 2VO0; 2VO3; 2VO6; 2VO7; 3AMA; 3AMB; 3L9L; 3L9M; 3L9N; 3MVJ; 3NX8; 3OOG; 3OVV; 3OWP; 3OXT; 3P0M; 3POO; 3VQH; 3WYG; 4AXA; 4IAC; 4IAD; 4IAF; 4IAI; 4IAK; 4IAY; 4IAZ; 4IB0; 4IB1; 4IB3; 4IE9; 4IJ9; 4O21; 4O22; 4WB5; 4WB6; 4WB7; 4WB8; 5DH9	20.5%
7	TOP2A	P11388	DNA topoisomerase 2-alpha	hsa01524	1LWZ; 1ZXM; 1ZXN; 4FM9; 4R1F	20.0%
8	AMY2A	P04746	Pancreatic alpha-amylase	hsa00500; hsa01100; hsa04972; hsa04973	1B2Y; 1BSI; 1CPU; 1HNY; 1KB3; 1KBB; 1KBK; 1KGU; 1KGW; 1KGX; 1U2Y; 1U30; 1U33; 1XCW; 1XCX; 1XD0; 1XD1; 1XGZ; 1XH0; 1XH1; 1XH2; 2CPU; 2QMK; 2QV4; 3BAI; 3BAJ; 3BAK; 3BAW; 3BAX; 3BAY; 3CPU; 3IJ7; 3IJ8; 3IJ9; 3OLD; 3OLE; 3OLG; 3OLI; 4GQQ; 4GQR; 4W93; 4X9Y	19.6%
9	PLAT	P00750	Tissue-type plasminogen activator	hsa04371; hsa04610; hsa05202; hsa05215; hsa05418	1A5H; 1BDA; 1PK2; 1PML; 1RTF; 1TPG; 1TPK; 1TPM; 1TPN; 5BRR	18.7%
10	BLVRB	P30043	Flavin reductase (NADPH)	hsa00740; hsa00860; hsa01100	1HDO; 1HE2; 1HE3; 1HE4; 1HE5	17.9%
11	PGD	P52209	6-phosphogluconate dehydrogenase, decarboxylating	hsa00030; hsa00480; hsa01100; hsa01200	2JKV; 4GWG; 4GWK	17.9%
12	ARG1	P05089	Arginase-1	hsa00220; hsa00330; hsa01100; hsa01230; hsa05146	1WVA; 1WVB; 2AEB; 2PHA; 2PHO; 2PLL; 2ZAV; 3DJ8; 3E6K; 3E6V; 3F80; 3GMZ; 3GN0; 3KV2; 3LP4; 3LP7; 3MFV; 3MFW; 3MJL; 3SJT; 3SKK; 3TF3; 3TH7; 3THE; 3THH; 3THJ; 4FCI; 4FCK; 4GSM; 4GSV; 4GSZ; 4GWC; 4GWD; 4HWW; 4HXQ; 4IE1	17.8%
13	CMA1	P23946	Chymase	hsa04614	1KLT; 1NN6; 1PJP; 1T31; 2HVX; 3N7O; 3S0N; 4AFQ; 4AFS; 4AFU; 4AFZ; 4AG1; 4AG2; 4K2Y; 4K5Z; 4K60; 4K69; 4KP0	17.6%
14	CTRB1	P17538	Chymotrypsinogen B	hsa04972; hsa04974	NA	17.1%
15	TYMS	P04818	Thymidylate synthase	hsa00240; hsa00670; hsa01100; hsa01523	1HVY; 1HW3; 1HW4; 1HZW; 1I00; 1JU6; 1JUJ; 1YPV; 2ONB; 2RD8; 2RDA; 3EAW; 3EBU; 3ED7; 3EDW; 3EF9; 3EGY; 3EHI; 3EJL; 3GG5; 3GH0; 3GH2; 3H9K; 3HB8; 3N5E; 3N5G; 3OB7; 4E28; 4FGT; 4G2O; 4G6W; 4GD7; 4GYH; 4H1I; 4JEF; 4KPW; 4O1U; 4O1X; 4UP1	17.0%
16	DHFR	P00374	Dihydrofolate reductase	hsa00670; hsa00790; hsa01100; hsa01523	1BOZ; 1DHF; 1DLR; 1DLS; 1DRF; 1HFP; 1HFQ; 1HFR; 1KMS; 1KMV; 1MVS; 1MVT; 1OHJ; 1OHK; 1PD8; 1PD9; 1PDB; 1S3U; 1S3V; 1S3W; 1U71; 1U72; 1YHO; 2C2S; 2C2T; 2DHF; 2W3A; 2W3B; 2W3M; 3EIG; 3F8Y; 3F8Z; 3F91; 3FS6; 3GHC; 3GHV; 3GHW; 3GI2; 3GYF; 3L3R; 3N0H; 3NTZ; 3NU0; 3NXO; 3NXR; 3NXT; 3NXV; 3NXX; 3NXY; 3NZD; 3OAF; 3S3V; 3S7A; 4DDR; 4G95; 4KAK; 4KBN; 4KD7; 4KEB; 4KFJ; 4M6J; 4M6K; 4M6L; 4QHV; 4QJC	17.0%
17	GNPDA1	P46926	Glucosamine-6-phosphate isomerase 1	hsa00520; hsa01100	1NE7	17.0%
18	CPB2	Q96IY4	Carboxypeptidase B2	hsa04610; hsa04972; hsa04974	3D66; 3D67; 3D68; 3LMS; 4P10	16.8%
19	F10	P00742	Coagulation factor X	hsa04610	1C5M; 1EZQ; 1F0R; 1F0S; 1FAX; 1FJS; 1FXY; 1G2L; 1G2M; 1HCG; 1IOE; 1IQE; 1IQF; 1IQG; 1IQH; 1IQI; 1IQJ; 1IQK; 1IQL; 1IQM; 1IQN; 1KSN; 1LPG; 1LPK; 1LPZ; 1LQD; 1MQ5; 1MQ6; 1MSX; 1NFU; 1NFW; 1NFX; 1NFY; 1NL8; 1P0S; 1V3X; 1WU1; 1XKA; 1XKB; 1Z6E; 2BMG; 2BOH; 2BOK; 2BQ6; 2BQ7; 2BQW; 2CJI; 2D1J; 2EI6; 2EI7; 2EI8; 2FZZ; 2G00; 2GD4; 2H9E; 2J2U; 2J34; 2J38; 2J4I; 2J94; 2J95; 2JKH; 2P16; 2P3F; 2P3T; 2P3U; 2P93; 2P94; 2P95; 2PHB; 2PR3; 2Q1J; 2RA0; 2UWL; 2UWO; 2UWP; 2VH0; 2VH6; 2VVC; 2VVU; 2VVV; 2VWL; 2VWM; 2VWN; 2VWO; 2W26; 2W3I; 2W3K; 2WYG; 2WYJ; 2XBV; 2XBW; 2XBX; 2XBY; 2XC0; 2XC4; 2XC5; 2Y5F; 2Y5G; 2Y5H; 2Y7X; 2Y7Z; 2Y80; 2Y81; 2Y82; 3CEN; 3CS7; 3ENS; 3FFG; 3HPT; 3IIT; 3K9X; 3KL6; 3KQB; 3KQC; 3KQD; 3KQE; 3LIW; 3M36; 3M37; 3Q3K; 3SW2; 3TK5; 3TK6; 4A7I; 4BTI; 4BTT; 4BTU; 4Y6D; 4Y71; 4Y76; 4Y79; 4Y7A; 4Y7B	16.7%
20	KIF1A	Q12756	Kinesin-like protein KIF1A	NA	4EGX; 4EJQ; 4UXO; 4UXP; 4UXR; 4UXS	16.6%