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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P06401

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PGR	P06401	Progesterone receptor	hsa04114; hsa04914; hsa04915; hsa05224	1A28; 1E3K; 1SQN; 1SR7; 1ZUC; 2C7A; 2OVH; 2OVM; 2W8Y; 3D90; 3G8O; 3HQ5; 3KBA; 3ZR7; 3ZRA; 3ZRB; 4A2J; 4APU; 4OAR

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Investigational	SmallMoleculeDrug	DB04787	Tanaproget	CN1C(=CC=C1C1=CC=C2NC(=S)OC(C)(C)C2=C1)C#N
2	Approved; Withdrawn	SmallMoleculeDrug	DB00431	Lindane	Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl
3	Approved	SmallMoleculeDrug	DB01428	Oxybenzone	COC1=CC(O)=C(C=C1)C(=O)C1=CC=CC=C1
4	Approved	SmallMoleculeDrug	DB13857	Demegestone	[H][C@@]12CC[C@](C)(C(C)=O)[C@@]1(C)CCC1=C3CCC(=O)C=C3CC[C@@]21[H]
5	Approved	SmallMoleculeDrug	DB09389	Norgestrel	CCC12CCC3C(CCC4=CC(=O)CCC34)C1CCC2(O)C#C
6	Approved	SmallMoleculeDrug	DB09124	Medrogestone	[H][C@@]12CC[C@](C)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C
7	Approved; Investigational	SmallMoleculeDrug	DB00294	Etonogestrel	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
8	Approved	SmallMoleculeDrug	DB00717	Norethisterone	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
9	Approved	SmallMoleculeDrug	DB01431	Allylestrenol	[H][C@@]12CC[C@@](O)(CC=C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]
10	Approved; Investigational	SmallMoleculeDrug	DB00367	Levonorgestrel	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
11	Experimental	SmallMoleculeDrug	DB02746	Phthalic Acid	OC(=O)C1=CC=CC=C1C(O)=O
12	Approved; Investigational	SmallMoleculeDrug	DB00957	Norgestimate	[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O
13	Approved; Investigational	SmallMoleculeDrug	DB06713	Norelgestromin	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(C=C3CC[C@@]21[H])=NO
14	Investigational	SmallMoleculeDrug	DB05253	Proellex	NA
15	Approved	SmallMoleculeDrug	DB00304	Desogestrel	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]
16	Approved; Vet approved	SmallMoleculeDrug	DB00764	Mometasone	[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
17	Approved	SmallMoleculeDrug	DB01406	Danazol	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC3=C(C[C@]12C)C=NO3
18	Approved	SmallMoleculeDrug	DB11619	Gestrinone	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H]
19	Approved	SmallMoleculeDrug	DB09123	Dienogest	[H][C@@]12CC[C@@](O)(CC#N)[C@@]1(C)CCC1=C3CCC(=O)C=C3CC[C@@]21[H]
20	Approved	SmallMoleculeDrug	DB00823	Ethynodiol diacetate	[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CC[C@H](OC(C)=O)C=C3CC[C@@]21[H]
21	Approved	SmallMoleculeDrug	DB00421	Spironolactone	[H][C@@]12CC[C@@]3(CCC(=O)O3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@]([H])(CC2=CC(=O)CC[C@]12C)SC(C)=O
22	Approved; Vet approved	SmallMoleculeDrug	DB00396	Progesterone	[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
23	Approved; Investigational	SmallMoleculeDrug	DB11064	Homosalate	NA
24	Approved; Investigational	SmallMoleculeDrug	DB00834	Mifepristone	[H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](C1=CC=C(C=C1)N(C)C)C1=C3CCC(=O)C=C3CC[C@@]21[H]
25	Investigational	SmallMoleculeDrug	DB06680	Asoprisnil	[H]\C(=N/O)C1=CC=C(C=C1)[C@@]1([H])C[C@@]2(C)[C@@]([H])(CC[C@]2(COC)OC)[C@]2([H])CCC3=CC(=O)CCC3=C12
26	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB00378	Dydrogesterone	[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@]1([H])[C@@]2([H])C=CC2=CC(=O)CC[C@@]12C
27	Approved; Investigational	SmallMoleculeDrug	DB06789	Hydroxyprogesterone caproate	[H][C@@]12CC[C@](OC(=O)CCCCC)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
28	Approved; Investigational	SmallMoleculeDrug	DB00603	Medroxyprogesterone acetate	[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)CC[C@]12C
29	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00351	Megestrol acetate	[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C
30	Approved	SmallMoleculeDrug	DB01395	Drospirenone	[H][C@@]12C[C@]1([H])[C@@]1([H])[C@]3([H])[C@]4([H])C[C@]4([H])[C@@]4(CCC(=O)O4)[C@@]3(C)CC[C@]1([H])[C@@]1(C)CCC(=O)C=C21
31	Approved	SmallMoleculeDrug	DB08867	Ulipristal	CN(C)C1=CC=C(C=C1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]2(O)C(C)=O)[C@@H]2CCC3=CC(=O)CCC3=C12
32	Approved	SmallMoleculeDrug	DB00588	Fluticasone propionate	[H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
33	Experimental	SmallMoleculeDrug	DB02998	Methyltrienolone	[H][C@@]12CC[C@](C)(O)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H]
34	Approved	SmallMoleculeDrug	DB00648	Mitotane	ClC(Cl)C(C1=CC=C(Cl)C=C1)C1=CC=CC=C1Cl
35	Approved	SmallMoleculeDrug	DB11219	Enzacamene	CC1=CC=C(\C=C2/C3CCC(C)(C2=O)C3(C)C)C=C1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB09130	Copper	[Cu]		72.9%
2	Approved; Investigational	SmallMoleculeDrug	DB01593	Zinc	[Zn]		60.8%
3	Approved; Illicit	SmallMoleculeDrug	DB01185	Fluoxymesterone	[H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)CC[C@]12C		55.0%
4	Illicit; Investigational	SmallMoleculeDrug	DB02901	Stanolone	[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C		52.4%
5	Experimental; Investigational	SmallMoleculeDrug	DB04216	Quercetin	OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1		50.0%
6	Approved	SmallMoleculeDrug	DB13944	Testosterone enanthate	[H][C@@]12CC[C@H](OC(=O)CCCCCC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C		49.3%
7	Approved	SmallMoleculeDrug	DB13943	Testosterone cypionate	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2OC(=O)CCC1CCCC1		46.8%
8	Approved	SmallMoleculeDrug	DB09086	Eugenol	COC1=C(O)C=CC(CC=C)=C1		44.9%
9	Experimental	SmallMoleculeDrug	DB02757	Pyrazole	N1C=CC=N1		44.6%
10	Approved; Investigational	SmallMoleculeDrug	DB13946	Testosterone undecanoate	CCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C		44.4%
11	Approved; Investigational	SmallMoleculeDrug	DB00624	Testosterone	[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C		43.9%
12	Approved; Investigational	SmallMoleculeDrug	DB00687	Fludrocortisone	[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)CC[C@]12C		42.4%
13	Approved	SmallMoleculeDrug	DB06710	Methyltestosterone	[H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C		42.1%
14	Approved	SmallMoleculeDrug	DB00655	Estrone	[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C=C3		41.9%
15	Approved	SmallMoleculeDrug	DB00841	Dobutamine	CC(CCC1=CC=C(O)C=C1)NCCC1=CC(O)=C(O)C=C1		41.8%
16	Experimental	SmallMoleculeDrug	DB13951	Stanolone acetate	CC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C		41.5%
17	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB01708	Prasterone	[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@]([H])(O)CC[C@]12C		40.2%
18	Approved	SmallMoleculeDrug	DB00675	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1		40.2%
19	Approved; Withdrawn	SmallMoleculeDrug	DB04824	Phenolphthalein	OC1=CC=C(C=C1)C1(OC(=O)C2=CC=CC=C12)C1=CC=C(O)C=C1		39.7%
20	Experimental	SmallMoleculeDrug	DB02266	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F		39.5%