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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q8NER1
No. Gene UniProt ID Protein Name Pathway PDB
1 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 hsa04080; hsa04750 NA


17 known interactions (drugs) of input target (TRPV1): Transient receptor potential cation channel subfamily V member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical		 SmallMoleculeDrug DB00132 Alpha-Linolenic Acid Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB09288 Propacetamol Thumb
3 Approved SmallMoleculeDrug DB06774 Capsaicin Thumb
4 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb
5 Approved;
Investigational		 SmallMoleculeDrug DB09120 Zucapsaicin Thumb
6 Approved SmallMoleculeDrug DB00316 Acetaminophen Thumb
7 Approved SmallMoleculeDrug DB01744 Camphor Thumb
8 Experimental SmallMoleculeDrug DB02955 Ricinoleic Acid Thumb
9 Approved;
Nutraceutical		 SmallMoleculeDrug DB00159 Icosapent Thumb
10 Experimental SmallMoleculeDrug DB11345 (S)-camphor Thumb
11 Approved;
Nutraceutical		 SmallMoleculeDrug DB00168 Aspartame Thumb
12 Investigational SmallMoleculeDrug DB11324 Nonivamide Thumb
13 Investigational SmallMoleculeDrug DB06515 Resiniferatoxin Thumb
14 Approved;
Investigational		 SmallMoleculeDrug DB14011 Nabiximols Thumb
15 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb
16 Approved BiotechDrug DB11131 Capsicum oleoresin Thumb
17 Investigational SmallMoleculeDrug DB14050 Cannabidivarin Thumb


20 predicted interactions (drugs) of input target (TRPV1): Transient receptor potential cation channel subfamily V member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Investigational SmallMoleculeDrug DB11755 Tetrahydrocannabivarin Thumb 55.5%
2 Approved SmallMoleculeDrug DB00825 Menthol Thumb 48.5%
3 Approved;
Nutraceutical		 SmallMoleculeDrug DB13961 Fish oil Thumb 38.9%
4 Approved;
Investigational		 SmallMoleculeDrug DB00486 Nabilone Thumb 34.3%
5 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB02709 Resveratrol Thumb 33.0%
6 Approved;
Illicit		 SmallMoleculeDrug DB00470 Dronabinol Thumb 32.9%
7 Approved;
Investigational		 SmallMoleculeDrug DB06155 Rimonabant Thumb 31.2%
8 Investigational SmallMoleculeDrug DB05077 SLV319 Thumb 30.3%
9 Approved;
Investigational;
Withdrawn		 BiotechDrug DB00055 Drotrecogin alfa Thumb 29.6%
10 Investigational;
Withdrawn		 SmallMoleculeDrug DB00197 Troglitazone Thumb 28.4%
11 Approved SmallMoleculeDrug DB09086 Eugenol Thumb 27.7%
12 Approved SmallMoleculeDrug DB00573 Fenoprofen Thumb 27.4%
13 Approved SmallMoleculeDrug DB01050 Ibuprofen Thumb 27.3%
14 Experimental SmallMoleculeDrug DB02379 Beta-D-Glucose Thumb 26.1%
15 Approved;
Vet approved		 SmallMoleculeDrug DB00945 Acetylsalicylic acid Thumb 25.7%
16 Approved;
Investigational		 SmallMoleculeDrug DB00482 Celecoxib Thumb 25.7%
17 Approved SmallMoleculeDrug DB00370 Mirtazapine Thumb 25.0%
18 Approved SmallMoleculeDrug DB00795 Sulfasalazine Thumb 24.8%
19 Approved;
Vet approved		 SmallMoleculeDrug DB01221 Ketamine Thumb 24.2%
20 Approved;
Nutraceutical		 SmallMoleculeDrug DB00170 Menadione Thumb 23.6%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.