QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9HB21
No. Gene UniProt ID Protein Name Pathway PDB
1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 NA 1EAZ


1 known interactions (drugs) of input target (PLEKHA1): Pleckstrin homology domain-containing family A member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB04272 Citric Acid Thumb


20 predicted interactions (drugs) of input target (PLEKHA1): Pleckstrin homology domain-containing family A member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb 21.9%
2 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00143 Glutathione Thumb 15.9%
3 Approved BiotechDrug DB08879 Belimumab Thumb 15.1%
4 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00162 Vitamin A Thumb 14.9%
5 Experimental SmallMoleculeDrug DB02098 Adenosine-2'-5'-Diphosphate Thumb 14.9%
6 Experimental SmallMoleculeDrug DB02805 Uracil arabinose-3'-phosphate Thumb 13.3%
7 Experimental SmallMoleculeDrug DB03661 Cysteinesulfonic Acid Thumb 12.6%
8 Experimental SmallMoleculeDrug DB03506 9-Deazaadenine Thumb 11.9%
9 Experimental SmallMoleculeDrug DB04166 Anthranilic acid Thumb 11.9%
10 Approved;
Experimental		 SmallMoleculeDrug DB03017 Lauric Acid Thumb 11.9%
11 Experimental SmallMoleculeDrug DB03981 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Thumb 11.8%
12 Investigational SmallMoleculeDrug DB05959 ENMD-1198 Thumb 11.6%
13 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00755 Tretinoin Thumb 11.4%
14 Experimental SmallMoleculeDrug DB03214 Vinylglycine Thumb 11.4%
15 Experimental SmallMoleculeDrug DB01752 S-adenosyl-L-homocysteine Thumb 11.4%
16 Experimental SmallMoleculeDrug DB07182 (2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID Thumb 11.0%
17 Investigational SmallMoleculeDrug DB05785 LGD-1550 Thumb 10.9%
18 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB01632 Alpha-Phosphoribosylpyrophosphoric Acid Thumb 10.8%
19 Experimental SmallMoleculeDrug DB02431 Cytidine-5'-Triphosphate Thumb 10.7%
20 Experimental;
Investigational		 SmallMoleculeDrug DB02745 Uridine Thumb 10.6%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.