QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: O43704
No. Gene UniProt ID Protein Name Pathway PDB
1 SULT1B1 O43704 Sulfotransferase family cytosolic 1B member 1 NA 2Z5F; 3CKL


1 known interactions (drugs) of input target (SULT1B1): Sulfotransferase family cytosolic 1B member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb


20 predicted interactions (drugs) of input target (SULT1B1): Sulfotransferase family cytosolic 1B member 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Nutraceutical		 SmallMoleculeDrug DB00128 L-Aspartic Acid Thumb 16.3%
2 Experimental SmallMoleculeDrug DB02098 Adenosine-2'-5'-Diphosphate Thumb 14.3%
3 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb 13.8%
4 Approved BiotechDrug DB13999 Moroctocog alfa Thumb 13.6%
5 Approved;
Investigational		 BiotechDrug DB00056 Gemtuzumab ozogamicin Thumb 13.0%
6 Experimental SmallMoleculeDrug DB04445 Mercuric iodide Thumb 12.8%
7 Approved BiotechDrug DB00054 Abciximab Thumb 12.8%
8 Experimental SmallMoleculeDrug DB02902 3'-Phosphate-Adenosine-5'-Phosphate Sulfate Thumb 12.7%
9 Approved;
Investigational		 BiotechDrug DB00087 Alemtuzumab Thumb 12.6%
10 Approved;
Investigational;
Withdrawn		 BiotechDrug DB00092 Alefacept Thumb 12.5%
11 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00119 Pyruvic acid Thumb 12.0%
12 Experimental SmallMoleculeDrug DB03346 3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol Thumb 11.6%
13 Approved;
Investigational		 BiotechDrug DB00110 Palivizumab Thumb 11.5%
14 Experimental SmallMoleculeDrug DB02264 O2-Sulfo-Glucuronic Acid Thumb 11.5%
15 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00720 Clodronic Acid Thumb 11.2%
16 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 11.1%
17 Investigational BiotechDrug DB06245 Lanoteplase Thumb 11.0%
18 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB13956 Estradiol valerate Thumb 10.9%
19 Experimental SmallMoleculeDrug DB03959 N,O6-Disulfo-Glucosamine Thumb 10.9%
20 Experimental SmallMoleculeDrug DB07130 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID Thumb 10.8%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.