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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q07973
No. Gene UniProt ID Protein Name Pathway PDB
1 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial hsa00100; hsa01100; hsa04928; hsa05206 NA

1 known interactions (drugs) of input target (CYP24A1): 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Investigational SmallMoleculeDrug DB05024 CTA018 Thumb

20 predicted interactions (drugs) of input target (CYP24A1): 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Experimental SmallMoleculeDrug DB04137 Guanosine-5'-Triphosphate Thumb 23.5%
2 Experimental SmallMoleculeDrug DB03814 2-(N-Morpholino)-Ethanesulfonic Acid Thumb 18.8%
3 Approved SmallMoleculeDrug DB06410 Doxercalciferol Thumb 15.2%
4 Approved;
SmallMoleculeDrug DB03615 Ribostamycin Thumb 14.7%
5 Approved SmallMoleculeDrug DB00780 Phenelzine Thumb 14.5%
6 Approved;
SmallMoleculeDrug DB09462 Glycerin Thumb 14.2%
7 Approved;
SmallMoleculeDrug DB04540 Cholesterol Thumb 14.1%
8 Investigational SmallMoleculeDrug DB06195 Seliciclib Thumb 13.9%
9 Investigational SmallMoleculeDrug DB05295 Eldecalcitol Thumb 13.1%
10 Approved;
Vet approved
SmallMoleculeDrug DB00396 Progesterone Thumb 13.0%
11 Experimental SmallMoleculeDrug DB07691 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid Thumb 12.8%
12 Investigational SmallMoleculeDrug DB04891 Becocalcidiol Thumb 12.4%
13 Approved;
SmallMoleculeDrug DB00126 Vitamin C Thumb 12.1%
14 Experimental SmallMoleculeDrug DB07530 (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol Thumb 11.8%
15 Approved SmallMoleculeDrug DB03754 Tromethamine Thumb 11.7%
16 Approved;
SmallMoleculeDrug DB00905 Bimatoprost Thumb 11.6%
17 Investigational SmallMoleculeDrug DB13930 Ulixertinib Thumb 11.5%
18 Approved;
SmallMoleculeDrug DB08908 Dimethyl fumarate Thumb 11.4%
19 Experimental SmallMoleculeDrug DB08163 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine Thumb 11.4%
20 Approved;
SmallMoleculeDrug DB00159 Icosapent Thumb 11.3%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.