QuartataWeb 1.0

7 known interactions (drugs) of input target (ITGA4): Integrin alpha-4

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Approved	SmallMoleculeDrug	DB06822	Tinzaparin	NA
2	Investigational	SmallMoleculeDrug	DB05092	CDP323	NA
3	Approved	BiotechDrug	DB09033	Vedolizumab	NA
4	Investigational	SmallMoleculeDrug	DB04997	ATL1102	NA
5	Investigational	SmallMoleculeDrug	DB05468	R411	NA
6	Investigational	SmallMoleculeDrug	DB05122	R1295	NA
7	Approved; Investigational	BiotechDrug	DB00108	Natalizumab	NA

20 predicted interactions (drugs) of input target (ITGA4): Integrin alpha-4

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Experimental	SmallMoleculeDrug	DB04315	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1	39.6%
2	Approved; Nutraceutical	SmallMoleculeDrug	DB00157	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O	36.0%
3	Approved	BiotechDrug	DB00051	Adalimumab	NA	26.5%
4	Approved; Investigational	BiotechDrug	DB00112	Bevacizumab	NA	26.2%
5	Approved; Investigational; Withdrawn	BiotechDrug	DB00092	Alefacept	NA	25.6%
6	Approved	BiotechDrug	DB00073	Rituximab	NA	24.4%
7	Approved; Investigational	BiotechDrug	DB00081	Tositumomab	NA	24.4%
8	Approved; Investigational	BiotechDrug	DB00110	Palivizumab	NA	23.5%
9	Approved; Nutraceutical	SmallMoleculeDrug	DB00142	Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O	23.3%
10	Approved; Investigational	BiotechDrug	DB00095	Efalizumab	NA	22.2%
11	Approved; Investigational	BiotechDrug	DB00078	Ibritumomab tiuxetan	NA	21.5%
12	Approved; Investigational	BiotechDrug	DB00005	Etanercept	NA	21.0%
13	Experimental	SmallMoleculeDrug	DB08342	S-PALMITOYL-L-CYSTEINE	[H][C@](N)(CSC(=O)CCCCCCCCCCCCCCC)C(O)=O	20.8%
14	Approved; Investigational	BiotechDrug	DB00056	Gemtuzumab ozogamicin	NA	20.5%
15	Experimental	SmallMoleculeDrug	DB08515	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	[H][C@](O)([C@@]1([H])CCCC=C1)[C@]1(NC(=O)[C@]2([H])CCO[C@]12C)C=O	19.9%
16	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB01404	Ginseng	NA	19.5%
17	Approved; Investigational	BiotechDrug	DB00072	Trastuzumab	NA	19.5%
18	Approved	SmallMoleculeDrug	DB00480	Lenalidomide	NC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O	19.0%
19	Experimental	SmallMoleculeDrug	DB04510	3-phospho-D-glyceric acid	O[C@H](COP(O)(O)=O)C(O)=O	18.8%
20	Investigational	SmallMoleculeDrug	DB12637	Onapristone	CN(C)C1=CC=C(C=C1)[C@H]1C[C@]2(C)[C@@H](CC[C@]2(O)CCCO)[C@@H]2CCC3=CC(=O)CCC3=C12	18.8%