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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P02788
No. Gene UniProt ID Protein Name Pathway PDB
1 LTF P02788 Lactotransferrin NA

7 known interactions (drugs) of input target (LTF): Lactotransferrin
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Experimental SmallMoleculeDrug DB03485 Alpha-D-Fucose Thumb
2 Approved;
SmallMoleculeDrug DB03017 Lauric Acid Thumb
3 Approved SmallMoleculeDrug DB08439 Parecoxib Thumb
4 Experimental SmallMoleculeDrug DB03040 Nitrilotriacetic Acid Thumb
5 Approved;
SmallMoleculeDrug DB04743 Nimesulide Thumb
6 Experimental SmallMoleculeDrug DB06987 2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE Thumb
7 Experimental SmallMoleculeDrug DB01811 3h-Indole-5,6-Diol Thumb

20 predicted interactions (drugs) of input target (LTF): Lactotransferrin
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB00142 Glutamic Acid Thumb 31.8%
2 Approved;
Vet approved
SmallMoleculeDrug DB00162 Vitamin A Thumb 25.8%
3 Approved;
Vet approved
SmallMoleculeDrug DB00586 Diclofenac Thumb 24.7%
4 Approved SmallMoleculeDrug DB00233 Aminosalicylic Acid Thumb 24.3%
5 Approved SmallMoleculeDrug DB00570 Vinblastine Thumb 24.1%
6 Investigational SmallMoleculeDrug DB04725 Licofelone Thumb 22.5%
7 Experimental SmallMoleculeDrug DB02726 2-Phosphoglycolic Acid Thumb 21.6%
8 Approved;
SmallMoleculeDrug DB00482 Celecoxib Thumb 20.4%
9 Investigational SmallMoleculeDrug DB12548 Sparsentan Thumb 20.3%
10 Experimental SmallMoleculeDrug DB01955 1,4-Butanediol Thumb 20.2%
11 Approved SmallMoleculeDrug DB00795 Sulfasalazine Thumb 20.0%
12 Approved SmallMoleculeDrug DB11614 Rupatadine Thumb 19.9%
13 Investigational SmallMoleculeDrug DB05255 Ronacaleret Thumb 19.8%
14 Approved SmallMoleculeDrug DB01194 Brinzolamide Thumb 19.8%
15 Experimental SmallMoleculeDrug DB03346 3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol Thumb 18.9%
16 Approved;
SmallMoleculeDrug DB02325 Isopropyl Alcohol Thumb 18.6%
17 Experimental SmallMoleculeDrug DB04444 Tetrafluoroaluminate Ion Thumb 18.1%
18 Experimental SmallMoleculeDrug DB08515 (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE Thumb 18.1%
19 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 17.9%
20 Approved SmallMoleculeDrug DB00316 Acetaminophen Thumb 17.5%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.