QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: O60706
No. Gene UniProt ID Protein Name Pathway PDB
1 ABCC9 O60706 ATP-binding cassette sub-family C member 9 hsa02010 NA


3 known interactions (drugs) of input target (ABCC9): ATP-binding cassette sub-family C member 9
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved SmallMoleculeDrug DB01016 Glyburide Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB09220 Nicorandil Thumb
3 Investigational;
Nutraceutical		 SmallMoleculeDrug DB00171 ATP Thumb


20 predicted interactions (drugs) of input target (ABCC9): ATP-binding cassette sub-family C member 9
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational		 SmallMoleculeDrug DB01599 Probucol Thumb 20.3%
2 Approved;
Investigational		 SmallMoleculeDrug DB00845 Clofazimine Thumb 19.5%
3 Experimental SmallMoleculeDrug DB03401 1D-myo-inositol 1,4,5-trisphosphate Thumb 19.0%
4 Approved;
Vet approved		 SmallMoleculeDrug DB01154 Thiamylal Thumb 17.2%
5 Experimental SmallMoleculeDrug DB02010 Staurosporine Thumb 16.3%
6 Approved;
Investigational		 SmallMoleculeDrug DB09059 Atosiban Thumb 16.0%
7 Approved;
Investigational;
Withdrawn		 SmallMoleculeDrug DB00914 Phenformin Thumb 15.8%
8 Approved;
Investigational		 SmallMoleculeDrug DB01251 Gliquidone Thumb 14.8%
9 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00162 Vitamin A Thumb 14.8%
10 Approved SmallMoleculeDrug DB00570 Vinblastine Thumb 14.8%
11 Approved;
Investigational		 SmallMoleculeDrug DB11712 Tezacaftor Thumb 14.3%
12 Approved;
Nutraceutical		 SmallMoleculeDrug DB00156 L-Threonine Thumb 14.3%
13 Approved;
Investigational		 SmallMoleculeDrug DB09213 Dexibuprofen Thumb 13.9%
14 Approved;
Nutraceutical		 SmallMoleculeDrug DB00122 Choline Thumb 13.8%
15 Approved SmallMoleculeDrug DB00493 Cefotaxime Thumb 13.4%
16 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00143 Glutathione Thumb 13.2%
17 Experimental SmallMoleculeDrug DB03867 Meta-Nitro-Tyrosine Thumb 13.2%
18 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00131 Adenosine monophosphate Thumb 12.9%
19 Approved;
Investigational		 SmallMoleculeDrug DB00839 Tolazamide Thumb 12.8%
20 Experimental SmallMoleculeDrug DB03059 Acetoacetyl-CoA Thumb 12.7%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.