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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P01584

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	IL1B	P01584	Interleukin-1 beta	hsa01523; hsa04010; hsa04060; hsa04064; hsa04217; hsa04380; hsa04620; hsa04621; hsa04623; hsa04625; hsa04640; hsa04657; hsa04659; hsa04668; hsa04750; hsa04932; hsa04933; hsa04940; hsa05010; hsa05020; hsa05132; hsa05133; hsa05134; hsa05140; hsa05142; hsa05143; hsa05144; hsa05146; hsa05152; hsa05162; hsa05163; hsa05164; hsa05168; hsa05321; hsa05323; hsa05332; hsa05418	1HIB; 1I1B; 1IOB; 1ITB; 1L2H; 1S0L; 1T4Q; 1TOO; 1TP0; 1TWE; 1TWM; 21BI; 2I1B; 2KH2; 2NVH; 31BI; 3LTQ; 3O4O; 3POK; 41BI; 4DEP; 4G6J; 4G6M; 4GAF; 4GAI; 4I1B; 5BVP; 5I1B; 6I1B; 7I1B; 9ILB

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Approved; Investigational	SmallMoleculeDrug	DB11967	Binimetinib	CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3F)=C(C=C12)C(=O)NOCCO
2	Investigational	SmallMoleculeDrug	DB05412	Talmapimod	[H][C@]1(C)CN(C(=O)C2=C(Cl)C=C3N(C)C=C(C(=O)C(=O)N(C)C)C3=C2)[C@]([H])(C)CN1CC1=CC=C(F)C=C1
3	Approved	BiotechDrug	DB10772	Foreskin keratinocyte (neonatal)	NA
4	Investigational	SmallMoleculeDrug	DB05507	VX-765	NA
5	Investigational	BiotechDrug	DB12119	Gevokizumab	NA
6	Approved; Investigational	BiotechDrug	DB06372	Rilonacept	NA
7	Investigational	SmallMoleculeDrug	DB05133	VP025	NA
8	Investigational	SmallMoleculeDrug	DB05442	Etiprednol dicloacetate	[H][C@@]12CC[C@](OC(=O)C(Cl)Cl)(C(=O)OCC)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
9	Approved; Investigational	BiotechDrug	DB06168	Canakinumab	NA
10	Investigational	SmallMoleculeDrug	DB05470	VX-702	NC(=O)N(C1=CC=C(C(N)=O)C(=N1)C1=CC=C(F)C=C1F)C1=C(F)C=CC=C1F
11	Investigational	SmallMoleculeDrug	DB12140	Dilmapimod	CC1=CC(F)=CC=C1C1=C2C=CC(=O)N(C2=NC(NC(CO)CO)=N1)C1=C(F)C=CC=C1F
12	Approved; Investigational	SmallMoleculeDrug	DB01017	Minocycline	[H][C@@]12CC3=C(C(O)=CC=C3N(C)C)C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2
13	Approved; Investigational	SmallMoleculeDrug	DB05260	Gallium nitrate	[Ga+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O
14	Investigational	SmallMoleculeDrug	DB05767	Andrographolide	[H]\C(C[C@]1([H])C(=C)CC[C@]2([H])[C@](C)(CO)[C@]([H])(O)CC[C@@]12C)=C1/C(=O)OC[C@@]1([H])O

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved	BiotechDrug	DB10770	Foreskin fibroblast (neonatal)	NA		51.7%
2	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC		36.8%
3	Investigational	SmallMoleculeDrug	DB05513	Atiprimod	CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1		34.6%
4	Approved; Investigational	SmallMoleculeDrug	DB01296	Glucosamine	N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O		33.6%
5	Approved; Investigational	SmallMoleculeDrug	DB11638	Artenimol	[H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C([H])(O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4		33.6%
6	Approved; Investigational	SmallMoleculeDrug	DB09221	Polaprezinc	[Zn++].[H][C@@](CC1=CN=CN1)([N-]C(=O)CCN)C([O-])=O		31.1%
7	Investigational	SmallMoleculeDrug	DB05017	YSIL6	NA		30.5%
8	Approved; Nutraceutical	SmallMoleculeDrug	DB00157	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O		30.5%
9	Investigational	SmallMoleculeDrug	DB05744	CRx-139	NA		29.9%
10	Investigational	SmallMoleculeDrug	DB05869	Ethyl pyruvate	CCOC(=O)C(C)=O		29.8%
11	Approved; Investigational	SmallMoleculeDrug	DB01411	Pranlukast	O=C(NC1=C2OC(=CC(=O)C2=CC=C1)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1		29.2%
12	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00119	Pyruvic acid	CC(=O)C(O)=O		28.1%
13	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00114	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O		27.9%
14	Investigational	SmallMoleculeDrug	DB05004	AC162352	NA		27.6%
15	Investigational	SmallMoleculeDrug	DB05992	Plinabulin	CC(C)(C)C1=C(\C=C2/NC(=O)\C(NC2=O)=C\C2=CC=CC=C2)N=CN1		27.3%
16	Investigational; Nutraceutical	SmallMoleculeDrug	DB00171	ATP	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O		27.3%
17	Approved; Investigational	SmallMoleculeDrug	DB12267	Brigatinib	COC1=CC(=CC=C1NC1=NC=C(Cl)C(NC2=CC=CC=C2P(C)(C)=O)=N1)N1CCC(CC1)N1CCN(C)CC1		27.1%
18	Nutraceutical	SmallMoleculeDrug	DB00116	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1		26.9%
19	Investigational	SmallMoleculeDrug	DB05944	Varlitinib	C[C@@H]1COC(NC2=CC=C3N=CN=C(NC4=CC=C(OCC5=NC=CS5)C(Cl)=C4)C3=C2)=N1		26.8%
20	Approved; Investigational	BiotechDrug	DB00072	Trastuzumab	NA		26.4%