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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P21802

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	FGFR2	P21802	Fibroblast growth factor receptor 2	hsa01521; hsa04010; hsa04014; hsa04015; hsa04144; hsa04151; hsa04550; hsa04810; hsa05200; hsa05215; hsa05226; hsa05230	1DJS; 1E0O; 1EV2; 1GJO; 1II4; 1IIL; 1NUN; 1OEC; 1WVZ; 2FDB; 2PSQ; 2PVF; 2PVY; 2PWL; 2PY3; 2PZ5; 2PZP; 2PZR; 2Q0B; 3B2T; 3CAF; 3CLY; 3CU1; 3DAR; 3EUU; 3OJ2; 3OJM; 3RI1; 4J23; 4J95; 4J96; 4J97; 4J98; 4J99; 4WV1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Experimental	SmallMoleculeDrug	DB01901	Sucrosofate	OS(=O)(=O)OC[C@H]1O[C@@](COS(O)(=O)=O)(O[C@H]2O[C@H](COS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H]1OS(O)(=O)=O
2	Approved	BiotechDrug	DB10770	Foreskin fibroblast (neonatal)	NA
3	Approved; Investigational	SmallMoleculeDrug	DB01109	Heparin	NA
4	Approved	BiotechDrug	DB10772	Foreskin keratinocyte (neonatal)	NA
5	Approved	BiotechDrug	DB00039	Palifermin	NA
6	Approved	SmallMoleculeDrug	DB08896	Regorafenib	CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1
7	Experimental	SmallMoleculeDrug	DB02058	SU4984	OC1=NC2=CC=CC=C2C1CC1=CC=C(C=C1)N1CCN(CC1)C=O
8	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
9	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB01041	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
10	Approved	SmallMoleculeDrug	DB09079	Nintedanib	COC(=O)C1=CC2=C(C=C1)\C(=C(\NC1=CC=C(C=C1)N(C)C(=O)CN1CCN(C)CC1)C1=CC=CC=C1)C(O)=N2
11	Approved; Investigational	SmallMoleculeDrug	DB08901	Ponatinib	CN1CCN(CC2=CC=C(NC(=O)C3=CC(C#CC4=CN=C5C=CC=NN45)=C(C)C=C3)C=C2C(F)(F)F)CC1
12	Experimental	SmallMoleculeDrug	DB02491	4-[4-(1-Amino-1-Methylethyl)Phenyl]-5-Chloro-N-[4-(2-Morpholin-4-Ylethyl)Phenyl]Pyrimidin-2-Amine	CC(C)(N)C1=CC=C(C=C1)C1=NC(NC2=CC=C(CCN3CCOCC3)C=C2)=NC=C1Cl
13	Approved; Investigational	SmallMoleculeDrug	DB09078	Lenvatinib	COC1=C(C=C2C(OC3=CC(Cl)=C(NC(O)=NC4CC4)C=C3)=CC=NC2=C1)C(O)=N

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB01254	Dasatinib	CC1=NC(NC2=NC=C(S2)C(=O)NC2=C(C)C=CC=C2Cl)=CC(=N1)N1CCN(CCO)CC1		61.2%
2	Approved	SmallMoleculeDrug	DB06589	Pazopanib	CN(C1=CC2=NN(C)C(C)=C2C=C1)C1=CC=NC(NC2=CC=C(C)C(=C2)S(N)(=O)=O)=N1		47.5%
3	Approved; Investigational	SmallMoleculeDrug	DB00398	Sorafenib	CNC(=O)C1=NC=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=C1		46.0%
4	Investigational	SmallMoleculeDrug	DB05014	XL999	NA		39.8%
5	Investigational	SmallMoleculeDrug	DB06080	ABT-869	NA		39.3%
6	Approved	SmallMoleculeDrug	DB00619	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1		38.5%
7	Experimental	SmallMoleculeDrug	DB07525	3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine	COC1=CC=CC(CC2=CNC3=C2C=CC=N3)=C1		36.2%
8	Experimental	SmallMoleculeDrug	DB08577	3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE	CC1=CNC(\C=C2/C(=O)NC3=CC=CC=C23)=C1CCC(O)=O		35.9%
9	Approved; Investigational	SmallMoleculeDrug	DB01268	Sunitinib	CCN(CC)CCNC(=O)C1=C(C)NC(\C=C2/C(=O)NC3=C2C=C(F)C=C3)=C1C		33.6%
10	Investigational	SmallMoleculeDrug	DB05146	XL820	NA		31.8%
11	Investigational	SmallMoleculeDrug	DB05913	OSI-930	FC(F)(F)OC1=CC=C(NC(=O)C2=C(NCC3=CC=NC4=CC=CC=C34)C=CS2)C=C1		30.8%
12	Approved	SmallMoleculeDrug	DB00686	Pentosan Polysulfate	O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O		29.1%
13	Experimental	SmallMoleculeDrug	DB07840	(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol	COC1=CC(=CC=C1)C(\O)=C1/C=NC2=NC=CC(=C12)C1=CC(F)=CC(F)=C1		28.9%
14	Experimental	SmallMoleculeDrug	DB08238	5-AMINO-NAPHTALENE-2-MONOSULFONATE	NC1=CC=CC2=CC(=CC=C12)S(O)(=O)=O		28.8%
15	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O		28.3%
16	Approved; Investigational	SmallMoleculeDrug	DB04868	Nilotinib	CC1=CN(C=N1)C1=CC(=CC(NC(=O)C2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)=C1)C(F)(F)F		26.7%
17	Investigational	SmallMoleculeDrug	DB12742	Amuvatinib	S=C(NCC1=CC=C2OCOC2=C1)N1CCN(CC1)C1=NC=NC2=C1OC1=C2C=CC=C1		26.5%
18	Approved; Investigational	SmallMoleculeDrug	DB08875	Cabozantinib	COC1=CC2=C(C=C1OC)C(OC1=CC=C(NC(=O)C3(CC3)C(=O)NC3=CC=C(F)C=C3)C=C1)=CC=N2		25.5%
19	Approved	SmallMoleculeDrug	DB08910	Pomalidomide	NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O		25.0%
20	Approved; Investigational	SmallMoleculeDrug	DB06595	Midostaurin	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O)N(C)C(=O)C1=CC=CC=C1		25.0%