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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

8 known interactions (drugs) of input target (PRKCB): Protein kinase C beta type
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
SmallMoleculeDrug DB08862 Cholecystokinin Thumb
2 Approved SmallMoleculeDrug DB00675 Tamoxifen Thumb
3 Approved;
Vet approved
SmallMoleculeDrug DB14002 D-alpha-Tocopherol acetate Thumb
4 Approved;
Vet approved
SmallMoleculeDrug DB00163 Vitamin E Thumb
5 Investigational SmallMoleculeDrug DB08846 Ellagic Acid Thumb
6 Investigational SmallMoleculeDrug DB06486 Enzastaurin Thumb
7 Approved;
Vet approved
SmallMoleculeDrug DB14001 alpha-Tocopherol succinate Thumb
8 Experimental SmallMoleculeDrug DB01738 Phosphorylcolamine Thumb

20 predicted interactions (drugs) of input target (PRKCB): Protein kinase C beta type
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 40.7%
2 Investigational SmallMoleculeDrug DB06641 Perifosine Thumb 38.9%
3 Investigational SmallMoleculeDrug DB06451 Aprinocarsen Thumb 26.5%
4 Approved;
SmallMoleculeDrug DB02709 Resveratrol Thumb 24.5%
5 Approved SmallMoleculeDrug DB00468 Quinine Thumb 22.9%
6 Approved SmallMoleculeDrug DB05013 Ingenol Mebutate Thumb 22.4%
7 Approved SmallMoleculeDrug DB06777 Chenodeoxycholic acid Thumb 22.0%
8 Approved SmallMoleculeDrug DB00493 Cefotaxime Thumb 20.4%
9 Investigational SmallMoleculeDrug DB05169 AT9283 Thumb 20.1%
10 Approved;
SmallMoleculeDrug DB01248 Docetaxel Thumb 19.3%
11 Approved;
Vet approved
SmallMoleculeDrug DB06795 Mafenide Thumb 19.0%
12 Experimental SmallMoleculeDrug DB02506 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid Thumb 18.7%
13 Approved;
SmallMoleculeDrug DB00909 Zonisamide Thumb 18.5%
14 Approved SmallMoleculeDrug DB01039 Fenofibrate Thumb 18.2%
15 Approved SmallMoleculeDrug DB00594 Amiloride Thumb 18.1%
16 Investigational SmallMoleculeDrug DB05431 MLN-977 Thumb 17.8%
17 Approved;
Vet approved
SmallMoleculeDrug DB00586 Diclofenac Thumb 17.4%
18 Experimental SmallMoleculeDrug DB06905 (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid Thumb 17.3%
19 Investigational SmallMoleculeDrug DB06134 SNS-314 Thumb 17.3%
20 Investigational;
SmallMoleculeDrug DB00171 ATP Thumb 17.2%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.