QuartataWeb 1.0

8 known interactions (drugs) of input target (PRKCB): Protein kinase C beta type

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Approved; Investigational	SmallMoleculeDrug	DB08862	Cholecystokinin	NA
2	Approved	SmallMoleculeDrug	DB00675	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
3	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB14002	D-alpha-Tocopherol acetate	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
4	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00163	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
5	Investigational	SmallMoleculeDrug	DB08846	Ellagic Acid	OC1=C(O)C2=C3C(=C1)C(=O)OC1=C3C(=CC(O)=C1O)C(=O)O2
6	Investigational	SmallMoleculeDrug	DB06486	Enzastaurin	CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CN(C2CCN(CC3=CC=CC=N3)CC2)C2=CC=CC=C12
7	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB14001	alpha-Tocopherol succinate	[H][C@@](C)(CCCC(C)C)CCC[C@@]([H])(C)CCC[C@]1(C)CCC2=C(C)C(OC(=O)CCC(O)=O)=C(C)C(C)=C2O1
8	Experimental	SmallMoleculeDrug	DB01738	Phosphorylcolamine	NCCOP(O)(O)=O

20 predicted interactions (drugs) of input target (PRKCB): Protein kinase C beta type

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC	40.7%
2	Investigational	SmallMoleculeDrug	DB06641	Perifosine	CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1	38.9%
3	Investigational	SmallMoleculeDrug	DB06451	Aprinocarsen	NA	26.5%
4	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1	24.5%
5	Approved	SmallMoleculeDrug	DB00468	Quinine	[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)[C@H](O)C1=CC=NC2=CC=C(OC)C=C12	22.9%
6	Approved	SmallMoleculeDrug	DB05013	Ingenol Mebutate	OCC1=C[C@]2([H])C(=O)[C@]3(C=C(C)[C@H](OC(=O)C(\C)=C/C)[C@@]3(O)[C@@H]1O)[C@H](C)C[C@@]1([H])C(C)(C)[C@@]21[H]	22.4%
7	Approved	SmallMoleculeDrug	DB06777	Chenodeoxycholic acid	[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O	22.0%
8	Approved	SmallMoleculeDrug	DB00493	Cefotaxime	[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O	20.4%
9	Investigational	SmallMoleculeDrug	DB05169	AT9283	NA	20.1%
10	Approved; Investigational	SmallMoleculeDrug	DB01248	Docetaxel	[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C5=CC=CC=C5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C1=CC=CC=C1	19.3%
11	Approved; Vet approved	SmallMoleculeDrug	DB06795	Mafenide	NCC1=CC=C(C=C1)S(N)(=O)=O	19.0%
12	Experimental	SmallMoleculeDrug	DB02506	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	[H][C@@](C)(CC[C@]([H])(N)[C@]([H])(C)C(O)=O)C[C@]([H])(C)[C@]([H])(CC1=CC=CC=C1)OC	18.7%
13	Approved; Investigational	SmallMoleculeDrug	DB00909	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12	18.5%
14	Approved	SmallMoleculeDrug	DB01039	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1	18.2%
15	Approved	SmallMoleculeDrug	DB00594	Amiloride	NC(N)=NC(=O)C1=C(N)N=C(N)C(Cl)=N1	18.1%
16	Investigational	SmallMoleculeDrug	DB05431	MLN-977	NA	17.8%
17	Approved; Vet approved	SmallMoleculeDrug	DB00586	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl	17.4%
18	Experimental	SmallMoleculeDrug	DB06905	(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid	[H][C@](C)(\C=C(/C)\C=C\[C@]([H])(N)[C@]([H])(C)C(O)=O)[C@]([H])(CC1=CC=CC=C1)OC	17.3%
19	Investigational	SmallMoleculeDrug	DB06134	SNS-314	ClC1=CC=CC(NC(=O)NC2=NC=C(CCNC3=C4SC=CC4=NC=N3)S2)=C1	17.3%
20	Investigational; Nutraceutical	SmallMoleculeDrug	DB00171	ATP	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O	17.2%