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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P12235
No. Gene UniProt ID Protein Name Pathway PDB
1 SLC25A4 P12235 ADP/ATP translocase 1 hsa04020; hsa04022; hsa04217; hsa04218; hsa05012; hsa05016; hsa05166 NA

6 known interactions (drugs) of input target (SLC25A4): ADP/ATP translocase 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
Vet approved
SmallMoleculeDrug DB00720 Clodronic Acid Thumb
2 Experimental SmallMoleculeDrug DB03429 Cardiolipin Thumb
3 Experimental SmallMoleculeDrug DB01736 [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Thumb
4 Experimental SmallMoleculeDrug DB04178 Di-Stearoyl-3-Sn-Phosphatidylcholine Thumb
5 Experimental SmallMoleculeDrug DB02426 Carboxyatractyloside Thumb
6 Investigational;
SmallMoleculeDrug DB00171 ATP Thumb

20 predicted interactions (drugs) of input target (SLC25A4): ADP/ATP translocase 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 31.2%
2 Approved;
SmallMoleculeDrug DB03247 Flavin mononucleotide Thumb 23.9%
3 Approved;
SmallMoleculeDrug DB00157 NADH Thumb 20.8%
4 Approved;
SmallMoleculeDrug DB00173 Adenine Thumb 20.1%
5 Investigational SmallMoleculeDrug DB06486 Enzastaurin Thumb 19.6%
6 Approved;
SmallMoleculeDrug DB00131 Adenosine monophosphate Thumb 19.4%
7 Approved;
SmallMoleculeDrug DB01254 Dasatinib Thumb 18.3%
8 Approved;
SmallMoleculeDrug DB13746 Bioallethrin Thumb 16.9%
9 Approved SmallMoleculeDrug DB06616 Bosutinib Thumb 16.8%
10 Experimental SmallMoleculeDrug DB03448 2'-Deoxyuridine 3'-Monophosphate Thumb 16.5%
11 Approved;
SmallMoleculeDrug DB00149 L-Leucine Thumb 16.5%
12 Approved SmallMoleculeDrug DB09079 Nintedanib Thumb 16.5%
13 Approved SmallMoleculeDrug DB06589 Pazopanib Thumb 16.2%
14 Experimental;
SmallMoleculeDrug DB03496 Alvocidib Thumb 15.4%
15 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb 15.1%
16 Experimental;
SmallMoleculeDrug DB04216 Quercetin Thumb 15.1%
17 Experimental SmallMoleculeDrug DB03959 N,O6-Disulfo-Glucosamine Thumb 15.0%
18 Investigational SmallMoleculeDrug DB12637 Onapristone Thumb 15.0%
19 Approved SmallMoleculeDrug DB00795 Sulfasalazine Thumb 14.6%
20 Investigational SmallMoleculeDrug DB06472 Fradafiban Thumb 14.5%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.