QuartataWeb 1.0

6 known interactions (drugs) of input target (A2M): Alpha-2-macroglobulin

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Approved; Investigational	SmallMoleculeDrug	DB12965	Silver	[Ag]
2	Approved	BiotechDrug	DB08888	Ocriplasmin	NA
3	Approved; Investigational	SmallMoleculeDrug	DB01593	Zinc	[Zn]
4	Approved	SmallMoleculeDrug	DB00515	Cisplatin	N[Pt](N)(Cl)Cl
5	Approved; Vet approved	SmallMoleculeDrug	DB00626	Bacitracin	CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC
6	Approved; Investigational	BiotechDrug	DB00102	Becaplermin	NA

20 predicted interactions (drugs) of input target (A2M): Alpha-2-macroglobulin

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB09130	Copper	[Cu]	45.4%
2	Experimental	SmallMoleculeDrug	DB03461	2'-Monophosphoadenosine 5'-Diphosphoribose	[H][C@]1(COP([O-])(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])([N+]3=CC=CC(=C3)C(O)=N)[C@]([H])(O)[C@]2([H])O)O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(OP(O)(O)=O)[C@]1([H])O	27.7%
3	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00145	Glycine	NCC(O)=O	24.4%
4	Approved; Investigational	SmallMoleculeDrug	DB11638	Artenimol	[H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C([H])(O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4	24.0%
5	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00155	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O	22.1%
6	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00114	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O	20.4%
7	Approved; Nutraceutical	SmallMoleculeDrug	DB06757	Manganese	[Mn++]	20.1%
8	Approved; Nutraceutical	SmallMoleculeDrug	DB01373	Calcium	[Ca]	19.3%
9	Approved; Nutraceutical	SmallMoleculeDrug	DB00123	L-Lysine	NCCCC[C@H](N)C(O)=O	18.7%
10	Experimental	SmallMoleculeDrug	DB07045	(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	[H][C@]1(CO)O[C@@]([H])(N2C(NCC3=CC=C(Cl)C(Cl)=C3)=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])O	18.7%
11	Approved; Investigational	SmallMoleculeDrug	DB01064	Isoprenaline	CC(C)NCC(O)C1=CC(O)=C(O)C=C1	18.3%
12	Approved; Investigational	SmallMoleculeDrug	DB05260	Gallium nitrate	[Ga+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O	18.2%
13	Approved; Investigational	SmallMoleculeDrug	DB00242	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1	18.0%
14	Experimental	SmallMoleculeDrug	DB03292	3-Phosphono-D-alanine	[H][C@@](N)(CP(O)(O)=O)C(O)=O	17.0%
15	Approved; Investigational	BiotechDrug	DB00030	Insulin Human	NA	16.8%
16	Approved	SmallMoleculeDrug	DB00471	Montelukast	OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(\C=C\C2=NC3=C(C=CC(Cl)=C3)C=C2)=C1	16.7%
17	Approved; Investigational	SmallMoleculeDrug	DB09462	Glycerin	OCC(O)CO	16.5%
18	Investigational	SmallMoleculeDrug	DB12548	Sparsentan	CCCCC1=NC2(CCCC2)C(=O)N1CC1=CC=C(C(COCC)=C1)C1=CC=CC=C1S(=O)(=O)NC1=NOC(C)=C1C	15.7%
19	Approved; Nutraceutical	SmallMoleculeDrug	DB00142	Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O	15.4%
20	Approved	BiotechDrug	DB00071	Insulin Pork	NA	14.6%