QuartataWeb 1.0

24 known interactions (drugs) of input target (IGHG1): Ig gamma-1 chain C region

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Experimental	SmallMoleculeDrug	DB07816	N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID	OC(=O)C\N=C(\NC(C1=CC=CC=C1)C1=CC=CC=C1)NC1=CC=C(C=C1)C#N
2	Experimental	SmallMoleculeDrug	DB07881	N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE	[H][C@](CC1=CC=CC=C1)(NC(=O)CCCC(O)=O)[P@](O)(=O)OCC(=O)NCCC1=CC=CC=C1
3	Experimental	SmallMoleculeDrug	DB07764	FLUORESCIN	OC(=O)C1=CC=CC=C1C1C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2
4	Experimental	SmallMoleculeDrug	DB08294	2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID	OC(=O)CC1=CC(=C(O)C=C1)[N+]([O-])=O
5	Experimental	SmallMoleculeDrug	DB08562	4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID	OC(=O)CCCC(=O)NC1=CC=C(\C=C\C2=CC=CC=C2)C=C1
6	Experimental	SmallMoleculeDrug	DB08377	N-[4-(4-nitrophenylphospho)butanoyl]-D-alanine	[H][C@](C)(N=C(O)CCCP(O)(=O)OC1=CC=C(C=C1)N(=O)=O)C(O)=O
7	Experimental	SmallMoleculeDrug	DB08412	6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID	OC(=O)CCCCCNC(=O)CCC[P@](O)(=O)OC1=CC=C(C=C1)[N+]([O-])=O
8	Experimental	SmallMoleculeDrug	DB08409	4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE	OC(=O)CNC(=O)CCC[P@@](O)(=O)OCC1=CC=C(C=C1)[N+]([O-])=O
9	Experimental	SmallMoleculeDrug	DB07883	(2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONE	[H][C@]12CC[C@]([H])(C1)[C@](N)(C(=O)C1=CC=CC=C1)[C@]2([H])C1=CC=CC=C1
10	Experimental	SmallMoleculeDrug	DB08394	PARA-NITROPHENYLPHOSPHONOBUTANOYL-GLYCINE	OC(=O)CNC(=O)CCC[P@](O)(=O)OC1=CC=C(C=C1)[N+]([O-])=O
11	Experimental	SmallMoleculeDrug	DB08296	5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID	OC(=O)CCCC[P@]([O-])(=O)OC1=CC=C(C=C1)[N+]([O-])=O
12	Experimental	SmallMoleculeDrug	DB07909	(1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL	[H][C@]1(O)C[C@]([H])(CC[C@]1([H])C1=CC=C(C=C1)C(=O)NCCCC(O)=O)C1=CC=CC=C1
13	Experimental	SmallMoleculeDrug	DB07672	TRANS-2-(DIMETHYLPHENYLSILYL)-PIPERIDINE-N-OXIDE	[H][C@@]1(CC[N@@+](C)([O-])CC1)[Si](C)(C)C1=CC=CC=C1
14	Experimental	SmallMoleculeDrug	DB07441	3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID	CN1C2=CC=CC=C2C(C#N)(C(=O)NCCC(O)=O)C2=C1C=CC=C2
15	Experimental	SmallMoleculeDrug	DB07371	3-(10-methyl-9-anthryl)propanoic acid	CC1=C2C=CC=CC2=C(CCC(O)=O)C2=C1C=CC=C2
16	Experimental	SmallMoleculeDrug	DB08332	9-(2-carboxyethyl)-10-methylanthracene endoperoxide	C[C@@]12OO[C@@](CCC(O)=O)(C3=C1C=CC=C3)C1=C2C=CC=C1
17	Experimental	SmallMoleculeDrug	DB08411	N-[4-(4-nitrophenylphospho)butanoyl]-L-alanine	[H][C@@](C)(NC(=O)CCC[P@](O)(=O)OC1=CC=C(C=C1)[N+]([O-])=O)C(O)=O
18	Experimental	SmallMoleculeDrug	DB04639	Biphenylalanine	[H][C@](N)(CC1=CC=C(C=C1)C1=CC=CC=C1)C(O)=O
19	Experimental	SmallMoleculeDrug	DB04473	Alpha-L-Fucose	C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
20	Experimental	SmallMoleculeDrug	DB03740	N-acetyl-alpha-D-glucosamine	[H][C@]1(O)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]1([H])N=C(C)O
21	Approved; Investigational	SmallMoleculeDrug	DB09130	Copper	[Cu]
22	Experimental	SmallMoleculeDrug	DB08410	PARA-NITROBENZYL GLUTARYL GLYCINIC ACID	OC(=O)CNC(=O)CCCC(=O)NCC1=CC=C(C=C1)[N+]([O-])=O
23	Experimental	SmallMoleculeDrug	DB01631	Methyl Nonanoate (Ester)	CCCCCCCCC(=O)OC
24	Experimental	SmallMoleculeDrug	DB07375	5-BETA-ANDROSTANE-3,17-DIONE	[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])CC(=O)CC[C@]12C

20 predicted interactions (drugs) of input target (IGHG1): Ig gamma-1 chain C region

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB01593	Zinc	[Zn]	55.0%
2	Approved; Investigational	SmallMoleculeDrug	DB11638	Artenimol	[H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C([H])(O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4	35.7%
3	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00145	Glycine	NCC(O)=O	32.1%
4	Experimental	SmallMoleculeDrug	DB04147	Lauryl Dimethylamine-N-Oxide	CCCCCCCCCCCC[N+](C)(C)[O-]	30.4%
5	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB01392	Yohimbine	[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2	27.9%
6	Experimental	SmallMoleculeDrug	DB07045	(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	[H][C@]1(CO)O[C@@]([H])(N2C(NCC3=CC=C(Cl)C(Cl)=C3)=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])O	27.7%
7	Experimental	SmallMoleculeDrug	DB01629	5-Fluorouridine	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=C(F)C(=O)NC1=O	27.1%
8	Approved; Withdrawn	SmallMoleculeDrug	DB11148	Butamben	CCCCOC(=O)C1=CC=C(N)C=C1	26.9%
9	Approved	SmallMoleculeDrug	DB09283	Trapidil	CCN(CC)C1=CC(C)=NC2=NC=NN12	26.6%
10	Approved; Investigational	SmallMoleculeDrug	DB12965	Silver	[Ag]	25.9%
11	Approved; Nutraceutical	SmallMoleculeDrug	DB00133	Serine	N[C@@H](CO)C(O)=O	25.9%
12	Approved; Investigational	SmallMoleculeDrug	DB01103	Quinacrine	CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2	25.6%
13	Experimental	SmallMoleculeDrug	DB08413	METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER	C[P@](O)(=O)OC1=CC=C(C=C1)[N+]([O-])=O	24.1%
14	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00114	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O	24.0%
15	Investigational	BiotechDrug	DB04985	Tigapotide	NA	24.0%
16	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00162	Vitamin A	C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C	24.0%
17	Approved	SmallMoleculeDrug	DB00421	Spironolactone	[H][C@@]12CC[C@@]3(CCC(=O)O3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@]([H])(CC2=CC(=O)CC[C@]12C)SC(C)=O	23.5%
18	Approved	SmallMoleculeDrug	DB00648	Mitotane	ClC(Cl)C(C1=CC=C(Cl)C=C1)C1=CC=CC=C1Cl	23.4%
19	Approved	SmallMoleculeDrug	DB00364	Sucralfate	O[Al](O)OS(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS(=O)(=O)O[Al](O)O)O[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]2OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]1OS(=O)(=O)O[Al](O)O	23.4%
20	Experimental	SmallMoleculeDrug	DB04117	4-(N,N-Dimethylamino)Cinnamoyl-Coa	[H]\C(=C(\[H])C1=CC=C(C=C1)N(C)C)C(=O)SCCN=C(O)CCN=C(O)[C@]([H])(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@@]1([H])O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])OP(O)(O)=O	23.1%