Home  |   About  |   Theory  |   Tutorials  |   FAQ  |   Bahar Lab  |   Statistics


Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q6UWM7
No. Gene UniProt ID Protein Name Pathway PDB
1 LCTL Q6UWM7 Lactase-like protein NA NA

5 known interactions (drugs) of input target (LCTL): Lactase-like protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Experimental SmallMoleculeDrug DB03430 (2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile Thumb
2 Experimental SmallMoleculeDrug DB08430 PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE Thumb
3 Experimental SmallMoleculeDrug DB02471 Nojirimycine Tetrazole Thumb
4 Experimental SmallMoleculeDrug DB02185 2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One Thumb
5 Experimental SmallMoleculeDrug DB02379 Beta-D-Glucose Thumb

20 predicted interactions (drugs) of input target (LCTL): Lactase-like protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB00157 NADH Thumb 32.8%
2 Approved;
SmallMoleculeDrug DB00755 Tretinoin Thumb 25.4%
3 Approved;
SmallMoleculeDrug DB11638 Artenimol Thumb 24.5%
4 Approved;
Vet approved
SmallMoleculeDrug DB04272 Citric Acid Thumb 24.2%
5 Approved;
SmallMoleculeDrug DB00313 Valproic Acid Thumb 21.4%
6 Approved;
SmallMoleculeDrug DB01041 Thalidomide Thumb 21.3%
7 Experimental SmallMoleculeDrug DB03721 N-acetyl-alpha-neuraminic acid Thumb 21.0%
8 Experimental SmallMoleculeDrug DB02007 alpha-D-glucose 6-phosphate Thumb 19.7%
9 Experimental SmallMoleculeDrug DB04544 1-Deoxy-1-Acetylamino-Beta-D-Gluco-2-Heptulopyranosonamide Thumb 19.6%
10 Approved SmallMoleculeDrug DB01016 Glyburide Thumb 18.5%
11 Experimental SmallMoleculeDrug DB04178 Di-Stearoyl-3-Sn-Phosphatidylcholine Thumb 18.4%
12 Approved;
Vet approved
SmallMoleculeDrug DB04224 Oleic Acid Thumb 18.4%
13 Experimental SmallMoleculeDrug DB01863 Inositol 1,3,4,5-Tetrakisphosphate Thumb 18.0%
14 Experimental SmallMoleculeDrug DB03354 2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole Thumb 16.8%
15 Approved;
SmallMoleculeDrug DB00174 L-Asparagine Thumb 16.7%
16 Approved;
SmallMoleculeDrug DB12965 Silver Thumb 16.7%
17 Approved;
SmallMoleculeDrug DB00159 Icosapent Thumb 16.6%
18 Experimental SmallMoleculeDrug DB07358 2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide Thumb 16.6%
19 Experimental SmallMoleculeDrug DB02964 8,9,10-Trihydroxy-7-Hydroxymethyl-2-Thioxo-6-Oxa-1,3-Diaza-Spiro[4.5]Decan-4-One Thumb 16.3%
20 Approved;
SmallMoleculeDrug DB05541 Brivaracetam Thumb 16.0%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.