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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P10828

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	THRB	P10828	Thyroid hormone receptor beta	hsa04080; hsa04919	1BSX; 1N46; 1NAX; 1NQ0; 1NQ1; 1NQ2; 1NUO; 1Q4X; 1R6G; 1XZX; 1Y0X; 2J4A; 2NLL; 2PIN; 3D57; 3GWS; 3IMY; 3JZC; 4ZO1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Experimental	SmallMoleculeDrug	DB03788	GC-24	CC1=CC(OCC(O)=O)=CC(C)=C1CC1=CC=C(O)C(CC2=CC=CC=C2)=C1
2	Approved	SmallMoleculeDrug	DB01583	Liotrix	[Na+].[Na+].N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C([O-])=O.N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C([O-])=O
3	Investigational	SmallMoleculeDrug	DB05192	MB07811	NA
4	Approved; Investigational	SmallMoleculeDrug	DB00509	Dextrothyroxine	N[C@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
5	Experimental	SmallMoleculeDrug	DB02106	[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid	OC(O)CC1=CC(Br)=C(OC2=CC(C(O)NCCC3=CC=CC=C3)=C(O)C=C2)C(Br)=C1
6	Experimental	SmallMoleculeDrug	DB03181	2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione	CC(C)C1=CC(OC2=C(C)C=C(C=C2C)N2N=CC(=O)NC2=O)=CC=C1O
7	Investigational	SmallMoleculeDrug	DB03604	Tiratricol	OC(=O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1
8	Investigational	SmallMoleculeDrug	DB05035	Eprotirome	CC(C)C1=CC(OC2=C(Br)C=C(NC(=O)CC(O)=O)C=C2Br)=CC=C1O
9	Experimental	SmallMoleculeDrug	DB08085	1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE	CCCCCCC1=CC=C(C=C1)C(=O)C=C
10	Approved; Investigational	SmallMoleculeDrug	DB01118	Amiodarone	CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2
11	Approved	SmallMoleculeDrug	DB00451	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
12	Approved; Vet approved	SmallMoleculeDrug	DB00279	Liothyronine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
13	Experimental	SmallMoleculeDrug	DB03176	KB-141	CC(C)C1=CC(OC2=C(Cl)C=C(CC(O)=O)C=C2Cl)=CC=C1O
14	Investigational	SmallMoleculeDrug	DB07425	Sobetirome	CC(C)C1=C(O)C=CC(CC2=C(C)C=C(OCC(O)=O)C=C2C)=C1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Investigational	SmallMoleculeDrug	DB05235	NRP409	NA		38.1%
2	Experimental	SmallMoleculeDrug	DB03461	2'-Monophosphoadenosine 5'-Diphosphoribose	[H][C@]1(COP([O-])(=O)OP(O)(=O)OC[C@@]2([H])O[C@@]([H])([N+]3=CC=CC(=C3)C(O)=N)[C@]([H])(O)[C@]2([H])O)O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(OP(O)(O)=O)[C@]1([H])O		28.9%
3	Approved; Illicit	SmallMoleculeDrug	DB00907	Cocaine	[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)C1=CC=CC=C1)C(=O)OC)N2C		27.9%
4	Experimental	SmallMoleculeDrug	DB03963	S-(Dimethylarsenic)Cysteine	[H][C@](N)(CS[As](C)C)C(O)=O		26.0%
5	Approved; Nutraceutical	SmallMoleculeDrug	DB00157	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O		26.0%
6	Investigational; Nutraceutical	SmallMoleculeDrug	DB01992	Coenzyme A	CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS		24.5%
7	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC		22.2%
8	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00721	Procaine	CCN(CC)CCOC(=O)C1=CC=C(N)C=C1		22.1%
9	Approved; Investigational	SmallMoleculeDrug	DB09099	Somatostatin	C[C@@H](O)[C@@H]1NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O		22.1%
10	Investigational	SmallMoleculeDrug	DB12695	Phenethyl Isothiocyanate	S=C=NCCC1=CC=CC=C1		22.0%
11	Nutraceutical	SmallMoleculeDrug	DB13191	Phosphocreatine	CN(CC(O)=O)C(=N)NP(O)(O)=O		21.9%
12	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00145	Glycine	NCC(O)=O		21.7%
13	Approved; Investigational	SmallMoleculeDrug	DB09034	Suvorexant	[H][C@@]1(C)CCN(CCN1C(=O)C1=C(C=CC(C)=C1)N1N=CC=N1)C1=NC2=C(O1)C=CC(Cl)=C2		20.9%
14	Approved; Investigational	SmallMoleculeDrug	DB04896	Milnacipran	CCN(CC)C(=O)[C@@]1(C[C@@H]1CN)C1=CC=CC=C1		20.7%
15	Approved; Vet approved	SmallMoleculeDrug	DB01213	Fomepizole	CC1=CNN=C1		20.3%
16	Approved	SmallMoleculeDrug	DB00805	Minaprine	CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1		20.3%
17	Approved	SmallMoleculeDrug	DB02659	Cholic Acid	[H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@]([H])(O)C[C@]4([H])C[C@]([H])(O)CC[C@]4(C)[C@@]3([H])C[C@]([H])(O)[C@]12C		20.2%
18	Approved; Investigational	SmallMoleculeDrug	DB04894	Vapreotide	[H][C@@](N)(CC1=CC=CC=C1)C(O)=N[C@@]1([H])CSSC[C@]([H])(N=C(O)[C@@]([H])(N=C(O)[C@]([H])(CCCCN)N=C(O)[C@@]([H])(CC2=CNC3=CC=CC=C23)N=C(O)[C@]([H])(CC2=CC=C(O)C=C2)N=C1O)C(C)C)C(O)=N[C@@]([H])(CC1=CNC2=CC=CC=C12)C(O)=N		19.9%
19	Approved; Investigational	SmallMoleculeDrug	DB01174	Phenobarbital	CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1		19.9%
20	Approved	SmallMoleculeDrug	DB06637	Dalfampridine	NC1=CC=NC=C1		19.9%