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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P15391
No. Gene UniProt ID Protein Name Pathway PDB
1 CD19 P15391 B-lymphocyte antigen CD19 hsa04151; hsa04640; hsa04662; hsa05169; hsa05340 NA

4 known interactions (drugs) of input target (CD19): B-lymphocyte antigen CD19
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
BiotechDrug DB13881 Tisagenlecleucel Thumb
2 Approved BiotechDrug DB13915 Axicabtagene ciloleucel Thumb
3 Approved;
BiotechDrug DB09052 Blinatumomab Thumb
4 Investigational BiotechDrug DB06342 Coltuximab ravtansine Thumb

20 predicted interactions (drugs) of input target (CD19): B-lymphocyte antigen CD19
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB09130 Copper Thumb 35.7%
2 Approved;
SmallMoleculeDrug DB04540 Cholesterol Thumb 25.7%
3 Approved;
SmallMoleculeDrug DB11638 Artenimol Thumb 25.7%
4 Experimental SmallMoleculeDrug DB02379 Beta-D-Glucose Thumb 24.4%
5 Approved;
SmallMoleculeDrug DB00149 L-Leucine Thumb 20.9%
6 Experimental;
SmallMoleculeDrug DB03496 Alvocidib Thumb 16.8%
7 Experimental;
SmallMoleculeDrug DB01565 Dihydromorphine Thumb 16.0%
8 Approved;
SmallMoleculeDrug DB00167 L-Isoleucine Thumb 16.0%
9 Approved SmallMoleculeDrug DB03147 Flavin adenine dinucleotide Thumb 15.9%
10 Experimental SmallMoleculeDrug DB02153 3-Sulfinoalanine Thumb 15.8%
11 Approved SmallMoleculeDrug DB00973 Ezetimibe Thumb 15.6%
12 Experimental SmallMoleculeDrug DB03435 Uridine-5'-Diphosphate Thumb 15.0%
13 Experimental SmallMoleculeDrug DB03389 alpha-D-Xylopyranose Thumb 15.0%
14 Experimental;
SmallMoleculeDrug DB02424 Geldanamycin Thumb 14.9%
15 Experimental SmallMoleculeDrug DB02935 Diglyme Thumb 14.9%
16 Approved SmallMoleculeDrug DB00836 Loperamide Thumb 14.8%
17 Approved;
SmallMoleculeDrug DB00119 Pyruvic acid Thumb 14.6%
18 Approved;
Vet approved
SmallMoleculeDrug DB00417 Phenoxymethylpenicillin Thumb 14.5%
19 Experimental SmallMoleculeDrug DB08848 Guvacine Thumb 14.2%
20 Investigational SmallMoleculeDrug DB14050 Cannabidivarin Thumb 13.8%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.