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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P09467

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	FBP1	P09467	Fructose-1,6-bisphosphatase 1	hsa00010; hsa00030; hsa00051; hsa01100; hsa01200; hsa04152; hsa04910; hsa04922	1FTA; 2FHY; 2FIE; 2FIX; 2JJK; 2VT5; 2WBB; 2WBD; 2Y5K; 2Y5L; 3A29; 3KBZ; 3KC0; 3KC1; 4MJO

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00131	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
2	Experimental	SmallMoleculeDrug	DB04175	Mdl-29951	OC(=O)CCC1=C(NC2=C1C(Cl)=CC(Cl)=C2)C(O)=O
3	Experimental	SmallMoleculeDrug	DB07312	2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE	ClC1=CC=C2OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=NC2=C1
4	Experimental	SmallMoleculeDrug	DB07321	2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE	COC1=CC2=C(OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=N2)C(=C1)C1=CN=C(OC)C=C1
5	Experimental	SmallMoleculeDrug	DB04493	Fructose-6-Phosphate	OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
6	Investigational	SmallMoleculeDrug	DB05053	MB-07803	CCOC(=O)C(C)(C)NP(=O)(NC(C)(C)C(=O)OCC)C1=CC=C(O1)C1=C(SC(N)=N1)C(=O)C(C)(C)C
7	Experimental	SmallMoleculeDrug	DB07270	N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE	COC1=CC2=C(OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=N2)C(=C1)C1=CC(N)=CC=C1
8	Experimental	SmallMoleculeDrug	DB08484	4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE	NC1=CC=C(C=C1)S(=O)(=O)NC(=O)NCCS
9	Investigational	SmallMoleculeDrug	DB05518	Managlinat dialanetil	[H][C@@](C)(NP(=O)(N[C@@]([H])(C)C(=O)OCC)C1=CC=C(O1)C1=C(CC(C)C)SC(=N)N1)C(=O)OCC
10	Experimental	SmallMoleculeDrug	DB02778	2,5-Anhydroglucitol-1,6-Biphosphate	[H][C@]1(O)[C@]([H])(O)[C@]([H])(COP(O)(O)=O)O[C@]1([H])COP(O)(O)=O
11	Experimental	SmallMoleculeDrug	DB02848	{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol	CCOC1=C(OCC)C=C2C(NC3=CC=CC(=C3)C3=CSC(CO)=N3)=NC=NC2=C1

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Experimental	SmallMoleculeDrug	DB04137	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1		27.8%
2	Approved	SmallMoleculeDrug	DB09283	Trapidil	CCN(CC)C1=CC(C)=NC2=NC=NN12		26.5%
3	Experimental	SmallMoleculeDrug	DB02755	1-3 Sugar Ring of Pentamannosyl 6-Phosphate	[H][C@]1(O)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O[C@@]2([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O[C@@]3([H])O[C@]([H])(COP(O)(O)=O)[C@@]([H])(O)[C@]([H])(O)[C@]3([H])O)[C@]2([H])O)[C@]1([H])O		26.3%
4	Approved	BiotechDrug	DB06404	Human C1-esterase inhibitor	NA		25.2%
5	Experimental	SmallMoleculeDrug	DB07403	4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE	CN(C)C(=O)C1=CC=C(C=C1)S(=O)(=O)C1=CC=C(NC(=O)[C@@](C)(O)C(F)(F)F)C(Cl)=C1		24.4%
6	Experimental	SmallMoleculeDrug	DB01752	S-adenosyl-L-homocysteine	N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O		23.9%
7	Approved; Nutraceutical	SmallMoleculeDrug	DB00139	Succinic acid	OC(=O)CCC(O)=O		23.4%
8	Approved; Investigational	SmallMoleculeDrug	DB08809	Dichloroacetic Acid	OC(=O)C(Cl)Cl		22.8%
9	Experimental	SmallMoleculeDrug	DB01863	Inositol 1,3,4,5-Tetrakisphosphate	O[C@H]1[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O		22.6%
10	Experimental	SmallMoleculeDrug	DB04331	Monastrol	[H][C@]1(NC(=S)NC(C)=C1C(=O)OCC)C1=CC=CC(O)=C1		22.4%
11	Experimental	SmallMoleculeDrug	DB02613	Decylamine-N,N-Dimethyl-N-Oxide	CCCCCCCCCC[N+](C)(C)[O-]		22.3%
12	Experimental	SmallMoleculeDrug	DB08562	4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID	OC(=O)CCCC(=O)NC1=CC=C(\C=C\C2=CC=CC=C2)C=C1		21.5%
13	Approved; Investigational	BiotechDrug	DB09228	Conestat alfa	NA		21.4%
14	Approved	SmallMoleculeDrug	DB00201	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C		21.1%
15	Approved; Investigational	SmallMoleculeDrug	DB09213	Dexibuprofen	[H][C@@](C)(C(O)=O)C1=CC=C(CC(C)C)C=C1		21.0%
16	Approved; Investigational	SmallMoleculeDrug	DB00724	Imiquimod	CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N		20.6%
17	Experimental	SmallMoleculeDrug	DB04315	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1		20.4%
18	Experimental	SmallMoleculeDrug	DB04363	Mesobiliverdin Iv Alpha	[H]\C(C1=C(C)C(CCC(O)=O)=C(N1)C(\[H])=C1/N=C(O)C(C)=C1CC)=C1\N=C(\C(\[H])=C2/N=C(O)C(C)=C2CC)C(CCC(O)=O)=C1C		20.1%
19	Approved	SmallMoleculeDrug	DB00674	Galantamine	[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3		19.9%
20	Experimental	SmallMoleculeDrug	DB03721	N-acetyl-alpha-neuraminic acid	[H][C@]1(O[C@](O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO		19.8%