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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P48067
No. Gene UniProt ID Protein Name Pathway PDB
1 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 NA NA


1 known interactions (drugs) of input target (SLC6A9): Sodium- and chloride-dependent glycine transporter 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


15 predicted interactions (drugs) of input target (SLC6A9): Sodium- and chloride-dependent glycine transporter 1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Investigational SmallMoleculeDrug DB12695 Phenethyl Isothiocyanate Thumb 21.5%
2 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb 16.8%
3 Approved;
Investigational		 SmallMoleculeDrug DB09130 Copper Thumb 15.8%
4 Approved;
Nutraceutical		 SmallMoleculeDrug DB00157 NADH Thumb 15.8%
5 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 15.0%
6 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 14.7%
7 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB00602 Ivermectin Thumb 12.7%
8 Approved;
Nutraceutical		 SmallMoleculeDrug DB00160 L-Alanine Thumb 12.2%
9 Experimental SmallMoleculeDrug DB04083 N'-Pyridoxyl-Lysine-5'-Monophosphate Thumb 11.6%
10 Approved;
Investigational		 SmallMoleculeDrug DB09401 Isosorbide Thumb 11.6%
11 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb 11.1%
12 Approved;
Nutraceutical		 SmallMoleculeDrug DB00129 Ornithine Thumb 10.9%
13 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 10.6%
14 Experimental SmallMoleculeDrug DB02467 L-methionine (S)-S-oxide Thumb 10.4%
15 Experimental SmallMoleculeDrug DB07557 (5BETA)-PREGNANE-3,20-DIONE Thumb 10.4%


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Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.