QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P11137
No. Gene UniProt ID Protein Name Pathway PDB
1 MAP2 P11137 Microtubule-associated protein 2 NA NA


3 known interactions (drugs) of input target (MAP2): Microtubule-associated protein 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational		 SmallMoleculeDrug DB01196 Estramustine Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB01248 Docetaxel Thumb
3 Approved;
Vet approved		 SmallMoleculeDrug DB01229 Paclitaxel Thumb


20 predicted interactions (drugs) of input target (MAP2): Microtubule-associated protein 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Withdrawn		 SmallMoleculeDrug DB00637 Astemizole Thumb 25.2%
2 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 23.5%
3 Approved SmallMoleculeDrug DB00675 Tamoxifen Thumb 22.3%
4 Approved;
Investigational		 SmallMoleculeDrug DB08871 Eribulin Thumb 21.7%
5 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB02789 Pregnenolone Thumb 19.9%
6 Investigational SmallMoleculeDrug DB01645 Genistein Thumb 19.5%
7 Approved;
Investigational		 SmallMoleculeDrug DB00309 Vindesine Thumb 19.2%
8 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb 18.3%
9 Approved;
Investigational		 SmallMoleculeDrug DB00448 Lansoprazole Thumb 18.0%
10 Approved SmallMoleculeDrug DB00655 Estrone Thumb 17.9%
11 Approved;
Investigational		 SmallMoleculeDrug DB06249 Arzoxifene Thumb 17.8%
12 Approved SmallMoleculeDrug DB11605 Myrrh Thumb 17.6%
13 Experimental;
Investigational		 SmallMoleculeDrug DB04216 Quercetin Thumb 17.5%
14 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 17.3%
15 Experimental SmallMoleculeDrug DB07150 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME Thumb 16.9%
16 Approved SmallMoleculeDrug DB00977 Ethinyl Estradiol Thumb 16.6%
17 Experimental SmallMoleculeDrug DB06927 [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE Thumb 16.3%
18 Approved SmallMoleculeDrug DB00376 Trihexyphenidyl Thumb 16.3%
19 Experimental SmallMoleculeDrug DB03309 N-Cyclohexyltaurine Thumb 16.1%
20 Approved;
Illicit;
Investigational		 SmallMoleculeDrug DB00182 Amphetamine Thumb 16.0%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.