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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q05315
No. Gene UniProt ID Protein Name Pathway PDB
1 CLC Q05315 Galectin-10 NA 1G86; 1HDK; 1LCL; 1QKQ


2 known interactions (drugs) of input target (CLC): Galectin-10
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Experimental SmallMoleculeDrug DB02967 N-Ethylmaleimide Thumb
2 Experimental SmallMoleculeDrug DB02983 Para-Mercury-Benzenesulfonic Acid Thumb


20 predicted interactions (drugs) of input target (CLC): Galectin-10
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved SmallMoleculeDrug DB00675 Tamoxifen Thumb 22.6%
2 Experimental SmallMoleculeDrug DB03467 Naringenin Thumb 18.4%
3 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00155 L-Citrulline Thumb 17.4%
4 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00118 Ademetionine Thumb 16.9%
5 Experimental SmallMoleculeDrug DB04137 Guanosine-5'-Triphosphate Thumb 16.9%
6 Experimental;
Investigational		 SmallMoleculeDrug DB04216 Quercetin Thumb 16.5%
7 Approved;
Investigational		 SmallMoleculeDrug DB09535 Octocrylene Thumb 16.3%
8 Investigational SmallMoleculeDrug DB04468 Afimoxifene Thumb 16.0%
9 Approved;
Investigational		 SmallMoleculeDrug DB00481 Raloxifene Thumb 15.8%
10 Experimental SmallMoleculeDrug DB02527 Cyclic Adenosine Monophosphate Thumb 15.1%
11 Approved;
Investigational		 BiotechDrug DB00048 Collagenase clostridium histolyticum Thumb 15.0%
12 Approved;
Nutraceutical		 SmallMoleculeDrug DB00133 Serine Thumb 14.8%
13 Approved;
Investigational		 SmallMoleculeDrug DB00716 Nedocromil Thumb 14.7%
14 Approved;
Investigational		 SmallMoleculeDrug DB11186 Pentoxyverine Thumb 13.9%
15 Experimental SmallMoleculeDrug DB07119 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL Thumb 13.9%
16 Experimental SmallMoleculeDrug DB08020 (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL Thumb 13.7%
17 Experimental SmallMoleculeDrug DB04736 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE Thumb 13.7%
18 Approved SmallMoleculeDrug DB00619 Imatinib Thumb 13.7%
19 Experimental SmallMoleculeDrug DB07032 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL Thumb 13.6%
20 Approved SmallMoleculeDrug DB01428 Oxybenzone Thumb 13.5%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.