QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9H598
No. Gene UniProt ID Protein Name Pathway PDB
1 SLC32A1 Q9H598 Vesicular inhibitory amino acid transporter hsa04721; hsa04723; hsa04727; hsa05032; hsa05033 NA


1 known interactions (drugs) of input target (SLC32A1): Vesicular inhibitory amino acid transporter
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


10 predicted interactions (drugs) of input target (SLC32A1): Vesicular inhibitory amino acid transporter
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 16.1%
2 Approved SmallMoleculeDrug DB00674 Galantamine Thumb 15.0%
3 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb 14.8%
4 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 14.5%
5 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 13.6%
6 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00144 Phosphatidyl serine Thumb 12.6%
7 Approved;
Investigational		 SmallMoleculeDrug DB00583 L-Carnitine Thumb 12.3%
8 Approved;
Nutraceutical		 SmallMoleculeDrug DB00129 Ornithine Thumb 11.6%
9 Experimental SmallMoleculeDrug DB04185 Norvaline Thumb 10.5%
10 Investigational SmallMoleculeDrug DB06486 Enzastaurin Thumb 10.4%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.