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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P30041
No. Gene UniProt ID Protein Name Pathway PDB
1 PRDX6 P30041 Peroxiredoxin-6 hsa01100 1PRX

3 known interactions (drugs) of input target (PRDX6): Peroxiredoxin-6
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
SmallMoleculeDrug DB02325 Isopropyl Alcohol Thumb
2 Approved;
SmallMoleculeDrug DB09130 Copper Thumb
3 Experimental SmallMoleculeDrug DB03814 2-(N-Morpholino)-Ethanesulfonic Acid Thumb

20 predicted interactions (drugs) of input target (PRDX6): Peroxiredoxin-6
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB01593 Zinc Thumb 57.0%
2 Approved;
SmallMoleculeDrug DB11638 Artenimol Thumb 37.9%
3 Experimental SmallMoleculeDrug DB04315 Guanosine-5'-Diphosphate Thumb 27.5%
4 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 26.4%
5 Approved;
SmallMoleculeDrug DB01254 Dasatinib Thumb 22.7%
6 Approved BiotechDrug DB00031 Tenecteplase Thumb 20.2%
7 Experimental SmallMoleculeDrug DB03216 (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine Thumb 19.8%
8 Experimental SmallMoleculeDrug DB03273 3'-Oxo-Adenosine Thumb 19.6%
9 Approved;
SmallMoleculeDrug DB01373 Calcium Thumb 19.5%
10 Experimental SmallMoleculeDrug DB03769 D-Eritadenine Thumb 18.2%
11 Experimental SmallMoleculeDrug DB04395 Phosphoaminophosphonic Acid-Adenylate Ester Thumb 17.4%
12 Approved SmallMoleculeDrug DB01592 Iron Thumb 16.9%
13 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb 16.7%
14 Investigational;
SmallMoleculeDrug DB00197 Troglitazone Thumb 16.5%
15 Approved;
Vet approved
SmallMoleculeDrug DB00396 Progesterone Thumb 15.1%
16 Investigational BiotechDrug DB06245 Lanoteplase Thumb 15.0%
17 Approved SmallMoleculeDrug DB03619 Deoxycholic Acid Thumb 14.6%
18 Experimental SmallMoleculeDrug DB02464 Benzylamine Thumb 14.5%
19 Experimental SmallMoleculeDrug DB04325 Phenethylamine Thumb 14.5%
20 Experimental SmallMoleculeDrug DB03976 Phosphorylisopropane Thumb 14.1%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.