QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P32239
No. Gene UniProt ID Protein Name Pathway PDB
1 CCKBR P32239 Gastrin/cholecystokinin type B receptor hsa04020; hsa04080; hsa04971 1L4T


2 known interactions (drugs) of input target (CCKBR): Gastrin/cholecystokinin type B receptor
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved SmallMoleculeDrug DB00183 Pentagastrin Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB08862 Cholecystokinin Thumb


20 predicted interactions (drugs) of input target (CCKBR): Gastrin/cholecystokinin type B receptor
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 26.6%
2 Investigational SmallMoleculeDrug DB04867 Lintitript Thumb 15.4%
3 Experimental SmallMoleculeDrug DB04604 5-iodotubercidin Thumb 15.3%
4 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00167 L-Isoleucine Thumb 15.0%
5 Approved;
Investigational		 SmallMoleculeDrug DB06603 Panobinostat Thumb 15.0%
6 Approved SmallMoleculeDrug DB00852 Pseudoephedrine Thumb 14.6%
7 Experimental SmallMoleculeDrug DB03909 Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Thumb 14.4%
8 Approved;
Nutraceutical		 SmallMoleculeDrug DB00173 Adenine Thumb 14.3%
9 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 13.9%
10 Experimental SmallMoleculeDrug DB01738 Phosphorylcolamine Thumb 13.7%
11 Approved;
Experimental		 SmallMoleculeDrug DB13751 Glycyrrhizic acid Thumb 13.5%
12 Approved SmallMoleculeDrug DB00288 Amcinonide Thumb 13.3%
13 Approved;
Investigational		 SmallMoleculeDrug DB06148 Mianserin Thumb 13.2%
14 Approved;
Investigational		 SmallMoleculeDrug DB13025 Tiapride Thumb 12.7%
15 Approved;
Investigational		 SmallMoleculeDrug DB05015 Belinostat Thumb 12.5%
16 Approved;
Investigational		 BiotechDrug DB09052 Blinatumomab Thumb 12.5%
17 Approved;
Investigational		 SmallMoleculeDrug DB04864 Huperzine A Thumb 12.4%
18 Approved;
Investigational		 SmallMoleculeDrug DB12332 Rucaparib Thumb 12.4%
19 Investigational SmallMoleculeDrug DB04856 Dexloxiglumide Thumb 12.4%
20 Experimental SmallMoleculeDrug DB04579 N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}- Thumb 12.2%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.