QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q07837
No. Gene UniProt ID Protein Name Pathway PDB
1 SLC3A1 Q07837 Neutral and basic amino acid transport protein rBAT hsa04974 NA


1 known interactions (drugs) of input target (SLC3A1): Neutral and basic amino acid transport protein rBAT
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical		 SmallMoleculeDrug DB00138 Cystine Thumb


18 predicted interactions (drugs) of input target (SLC3A1): Neutral and basic amino acid transport protein rBAT
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Investigational;
Nutraceutical		 SmallMoleculeDrug DB00171 ATP Thumb 22.0%
2 Approved;
Investigational		 SmallMoleculeDrug DB00740 Riluzole Thumb 14.9%
3 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb 13.2%
4 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb 13.0%
5 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 13.0%
6 Approved;
Investigational		 SmallMoleculeDrug DB04465 Lactose Thumb 12.9%
7 Approved SmallMoleculeDrug DB04855 Dronedarone Thumb 12.4%
8 Approved SmallMoleculeDrug DB01016 Glyburide Thumb 12.3%
9 Approved;
Nutraceutical		 SmallMoleculeDrug DB00136 Calcitriol Thumb 11.5%
10 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB11094 Vitamin D Thumb 11.5%
11 Investigational SmallMoleculeDrug DB04847 Roxadustat Thumb 11.0%
12 Investigational SmallMoleculeDrug DB12637 Onapristone Thumb 10.9%
13 Investigational SmallMoleculeDrug DB06670 Odanacatib Thumb 10.4%
14 Approved SmallMoleculeDrug DB06707 Levonordefrin Thumb 10.4%
15 Approved;
Investigational		 SmallMoleculeDrug DB12483 Copanlisib Thumb 10.4%
16 Experimental SmallMoleculeDrug DB03721 N-acetyl-alpha-neuraminic acid Thumb 10.4%
17 Approved;
Nutraceutical		 SmallMoleculeDrug DB00126 Vitamin C Thumb 10.4%
18 Approved SmallMoleculeDrug DB06589 Pazopanib Thumb 10.2%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.