QuartataWeb
Home  |   About  |   Theory  |   Tutorials  |   FAQ  |   Bahar Lab  |   Statistics
 

Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: STITCH; Query type: chemical; # of requested predictions: ; Secondary interactions: no
Input drug 1: 59054496
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1
Thumb


3 known interactions (drugs) of input target (NA): Serine hydroxymethyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb
2 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb
3 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


20 predicted interactions (drugs) of input target (NA): Serine hydroxymethyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Nutraceutical		 SmallMoleculeDrug DB00160 L-Alanine Thumb 35.1%
2 Approved;
Nutraceutical		 SmallMoleculeDrug DB00151 L-Cysteine Thumb 25.6%
3 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 23.9%
4 Approved;
Nutraceutical		 SmallMoleculeDrug DB00133 Serine Thumb 23.2%
5 Approved;
Nutraceutical		 SmallMoleculeDrug DB00115 Cyanocobalamin Thumb 22.0%
6 Approved;
Investigational		 SmallMoleculeDrug DB09130 Copper Thumb 20.6%
7 Experimental SmallMoleculeDrug DB02824 N-Pyridoxyl-Glycine-5-Monophosphate Thumb 17.6%
8 Experimental SmallMoleculeDrug DB02800 5-Hydroxymethylene-6-Hydrofolic Acid Thumb 17.2%
9 Approved;
Nutraceutical		 SmallMoleculeDrug DB00157 NADH Thumb 17.1%
10 Experimental SmallMoleculeDrug DB04083 N'-Pyridoxyl-Lysine-5'-Monophosphate Thumb 16.6%
11 Experimental SmallMoleculeDrug DB02067 Triglu-5-Formyl-Tetrahydrofolate Thumb 15.3%
12 Approved;
Investigational		 SmallMoleculeDrug DB00786 Marimastat Thumb 14.7%
13 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 14.7%
14 Approved SmallMoleculeDrug DB00200 Hydroxocobalamin Thumb 14.5%
15 Approved;
Vet approved		 SmallMoleculeDrug DB01159 Halothane Thumb 14.2%
16 Approved;
Nutraceutical		 SmallMoleculeDrug DB01956 Taurine Thumb 14.1%
17 Investigational SmallMoleculeDrug DB06354 Tezampanel Thumb 14.0%
18 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 14.0%
19 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00119 Pyruvic acid Thumb 13.9%
20 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00118 Ademetionine Thumb 13.8%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.