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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q6IB77
No. Gene UniProt ID Protein Name Pathway PDB
1 GLYAT Q6IB77 Glycine N-acyltransferase hsa00360 NA


1 known interactions (drugs) of input target (GLYAT): Glycine N-acyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


15 predicted interactions (drugs) of input target (GLYAT): Glycine N-acyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb 20.8%
2 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 17.3%
3 Experimental;
Investigational		 SmallMoleculeDrug DB03366 Imidazole Thumb 13.8%
4 Experimental SmallMoleculeDrug DB08231 Myristic acid Thumb 13.7%
5 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 13.1%
6 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 12.4%
7 Approved;
Investigational		 SmallMoleculeDrug DB08889 Carfilzomib Thumb 11.6%
8 Experimental SmallMoleculeDrug DB02740 3-Indolebutyric Acid Thumb 11.4%
9 Approved;
Nutraceutical		 SmallMoleculeDrug DB01956 Taurine Thumb 11.3%
10 Approved;
Investigational		 SmallMoleculeDrug DB00293 Raltitrexed Thumb 11.2%
11 Experimental SmallMoleculeDrug DB03408 gamma-Glutamylcysteine Thumb 11.1%
12 Approved SmallMoleculeDrug DB13146 Fluciclovine (18F) Thumb 10.8%
13 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb 10.5%
14 Experimental SmallMoleculeDrug DB07161 5-phenyl-1H-indazol-3-amine Thumb 10.4%
15 Approved;
Investigational		 SmallMoleculeDrug DB12267 Brigatinib Thumb 10.3%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.