QuartataWeb
Home  |   About  |   Theory  |   Tutorials  |   FAQ  |   Bahar Lab  |   Statistics
 

Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9Y345
No. Gene UniProt ID Protein Name Pathway PDB
1 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 NA NA


1 known interactions (drugs) of input target (SLC6A5): Sodium- and chloride-dependent glycine transporter 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


18 predicted interactions (drugs) of input target (SLC6A5): Sodium- and chloride-dependent glycine transporter 2
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 17.6%
2 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 17.2%
3 Approved;
Nutraceutical		 SmallMoleculeDrug DB00151 L-Cysteine Thumb 16.8%
4 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb 15.4%
5 Experimental SmallMoleculeDrug DB04395 Phosphoaminophosphonic Acid-Adenylate Ester Thumb 15.3%
6 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 14.7%
7 Approved;
Investigational		 SmallMoleculeDrug DB06151 Acetylcysteine Thumb 14.4%
8 Approved;
Nutraceutical		 SmallMoleculeDrug DB00160 L-Alanine Thumb 13.8%
9 Approved SmallMoleculeDrug DB09283 Trapidil Thumb 13.6%
10 Approved;
Nutraceutical		 SmallMoleculeDrug DB01956 Taurine Thumb 12.0%
11 Approved;
Investigational		 SmallMoleculeDrug DB12010 Fostamatinib Thumb 12.0%
12 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb 11.7%
13 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 11.7%
14 Approved;
Investigational;
Withdrawn		 BiotechDrug DB06607 Catumaxomab Thumb 11.2%
15 Approved SmallMoleculeDrug DB00949 Felbamate Thumb 10.6%
16 Experimental;
Illicit;
Investigational		 SmallMoleculeDrug DB01520 Tenocyclidine Thumb 10.4%
17 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb 10.3%
18 Approved;
Nutraceutical		 SmallMoleculeDrug DB00129 Ornithine Thumb 10.1%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.