QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9NZD2
No. Gene UniProt ID Protein Name Pathway PDB
1 GLTP Q9NZD2 Glycolipid transfer protein NA


5 known interactions (drugs) of input target (GLTP): Glycolipid transfer protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational		 SmallMoleculeDrug DB04465 Lactose Thumb
2 Experimental SmallMoleculeDrug DB03203 Sphingosine Thumb
3 Approved;
Experimental		 SmallMoleculeDrug DB03017 Lauric Acid Thumb
4 Experimental SmallMoleculeDrug DB03600 Capric acid Thumb
5 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB04224 Oleic Acid Thumb


20 predicted interactions (drugs) of input target (GLTP): Glycolipid transfer protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Experimental SmallMoleculeDrug DB02746 Phthalic Acid Thumb 28.0%
2 Experimental SmallMoleculeDrug DB08231 Myristic acid Thumb 26.8%
3 Approved;
Investigational		 SmallMoleculeDrug DB00412 Rosiglitazone Thumb 26.2%
4 Approved;
Investigational		 SmallMoleculeDrug DB01393 Bezafibrate Thumb 26.2%
5 Approved;
Investigational		 SmallMoleculeDrug DB02325 Isopropyl Alcohol Thumb 23.8%
6 Investigational SmallMoleculeDrug DB08846 Ellagic Acid Thumb 23.6%
7 Approved;
Investigational		 SmallMoleculeDrug DB12965 Silver Thumb 23.0%
8 Approved;
Investigational		 SmallMoleculeDrug DB00328 Indomethacin Thumb 22.9%
9 Investigational SmallMoleculeDrug DB05187 Elafibranor Thumb 22.7%
10 Approved SmallMoleculeDrug DB00562 Benzthiazide Thumb 22.3%
11 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 21.8%
12 Approved SmallMoleculeDrug DB00459 Acitretin Thumb 21.7%
13 Experimental SmallMoleculeDrug DB07724 Indeglitazar Thumb 21.5%
14 Approved;
Investigational		 SmallMoleculeDrug DB03756 Doconexent Thumb 21.4%
15 Approved SmallMoleculeDrug DB09006 Clinofibrate Thumb 21.2%
16 Experimental SmallMoleculeDrug DB03633 Lpc-Ether Thumb 20.7%
17 Experimental;
Investigational		 SmallMoleculeDrug DB04216 Quercetin Thumb 20.0%
18 Approved;
Investigational		 SmallMoleculeDrug DB04951 Pirfenidone Thumb 19.3%
19 Experimental SmallMoleculeDrug DB03435 Uridine-5'-Diphosphate Thumb 19.3%
20 Approved;
Investigational		 SmallMoleculeDrug DB00523 Alitretinoin Thumb 19.0%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.