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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: O60656
No. Gene UniProt ID Protein Name Pathway PDB
1 UGT1A9 O60656 UDP-glucuronosyltransferase 1-9 hsa00040; hsa00053; hsa00140; hsa00830; hsa00860; hsa00980; hsa00982; hsa00983; hsa01100; hsa05204 NA


2 known interactions (drugs) of input target (UGT1A9): UDP-glucuronosyltransferase 1-9
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved SmallMoleculeDrug DB04552 Niflumic Acid Thumb
2 Approved;
Withdrawn		 SmallMoleculeDrug DB04824 Phenolphthalein Thumb


20 predicted interactions (drugs) of input target (UGT1A9): UDP-glucuronosyltransferase 1-9
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved SmallMoleculeDrug DB09295 Talniflumate Thumb 25.8%
2 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 20.8%
3 Approved SmallMoleculeDrug DB00675 Tamoxifen Thumb 20.4%
4 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB02709 Resveratrol Thumb 19.9%
5 Approved SmallMoleculeDrug DB00421 Spironolactone Thumb 19.7%
6 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB01708 Prasterone Thumb 18.2%
7 Approved;
Investigational		 SmallMoleculeDrug DB00255 Diethylstilbestrol Thumb 17.6%
8 Approved;
Investigational		 SmallMoleculeDrug DB01026 Ketoconazole Thumb 17.3%
9 Approved;
Vet approved		 SmallMoleculeDrug DB00396 Progesterone Thumb 17.1%
10 Experimental;
Investigational		 SmallMoleculeDrug DB04216 Quercetin Thumb 16.8%
11 Investigational SmallMoleculeDrug DB04468 Afimoxifene Thumb 16.1%
12 Investigational;
Withdrawn		 SmallMoleculeDrug DB00197 Troglitazone Thumb 15.7%
13 Investigational SmallMoleculeDrug DB02342 2-Methoxyestradiol Thumb 15.6%
14 Approved;
Nutraceutical		 SmallMoleculeDrug DB00159 Icosapent Thumb 15.6%
15 Approved;
Investigational		 SmallMoleculeDrug DB00412 Rosiglitazone Thumb 15.5%
16 Approved;
Investigational;
Vet approved		 SmallMoleculeDrug DB04224 Oleic Acid Thumb 15.0%
17 Experimental SmallMoleculeDrug DB07657 PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER Thumb 14.9%
18 Investigational SmallMoleculeDrug DB01645 Genistein Thumb 14.9%
19 Approved SmallMoleculeDrug DB01620 Pheniramine Thumb 14.8%
20 Experimental SmallMoleculeDrug DB06833 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE Thumb 14.8%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.