QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q9P0Z9
No. Gene UniProt ID Protein Name Pathway PDB
1 PIPOX Q9P0Z9 Peroxisomal sarcosine oxidase hsa00260; hsa00310; hsa01100; hsa04146 NA


1 known interactions (drugs) of input target (PIPOX): Peroxisomal sarcosine oxidase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


20 predicted interactions (drugs) of input target (PIPOX): Peroxisomal sarcosine oxidase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 31.4%
2 Approved;
Nutraceutical		 SmallMoleculeDrug DB00129 Ornithine Thumb 17.6%
3 Approved;
Investigational		 SmallMoleculeDrug DB12010 Fostamatinib Thumb 17.1%
4 Experimental SmallMoleculeDrug DB04395 Phosphoaminophosphonic Acid-Adenylate Ester Thumb 16.7%
5 Approved;
Investigational		 SmallMoleculeDrug DB00909 Zonisamide Thumb 15.3%
6 Approved;
Nutraceutical		 SmallMoleculeDrug DB00151 L-Cysteine Thumb 14.0%
7 Approved SmallMoleculeDrug DB00619 Imatinib Thumb 13.9%
8 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 13.3%
9 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 12.5%
10 Nutraceutical SmallMoleculeDrug DB00116 Tetrahydrofolic acid Thumb 12.2%
11 Investigational;
Nutraceutical		 SmallMoleculeDrug DB00171 ATP Thumb 11.9%
12 Approved;
Vet approved		 SmallMoleculeDrug DB00945 Acetylsalicylic acid Thumb 11.7%
13 Approved;
Nutraceutical		 SmallMoleculeDrug DB00133 Serine Thumb 11.6%
14 Experimental SmallMoleculeDrug DB02482 Phosphonothreonine Thumb 11.6%
15 Experimental SmallMoleculeDrug DB02821 Canaline Thumb 11.3%
16 Approved;
Nutraceutical		 SmallMoleculeDrug DB00142 Glutamic Acid Thumb 11.1%
17 Approved SmallMoleculeDrug DB11590 Thimerosal Thumb 11.0%
18 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 10.9%
19 Experimental SmallMoleculeDrug DB08060 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID Thumb 10.8%
20 Approved;
Nutraceutical		 SmallMoleculeDrug DB00160 L-Alanine Thumb 10.8%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.