QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q14032
No. Gene UniProt ID Protein Name Pathway PDB
1 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase hsa00120; hsa00430; hsa01040; hsa01100; hsa04146; hsa04976 NA


1 known interactions (drugs) of input target (BAAT): Bile acid-CoA:amino acid N-acyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb


20 predicted interactions (drugs) of input target (BAAT): Bile acid-CoA:amino acid N-acyltransferase
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 27.6%
2 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 13.5%
3 Approved;
Investigational		 SmallMoleculeDrug DB12010 Fostamatinib Thumb 13.2%
4 Experimental SmallMoleculeDrug DB04395 Phosphoaminophosphonic Acid-Adenylate Ester Thumb 13.1%
5 Approved;
Nutraceutical		 SmallMoleculeDrug DB00149 L-Leucine Thumb 12.9%
6 Approved SmallMoleculeDrug DB00674 Galantamine Thumb 12.6%
7 Approved BiotechDrug DB08888 Ocriplasmin Thumb 12.3%
8 Investigational;
Nutraceutical		 SmallMoleculeDrug DB00171 ATP Thumb 12.2%
9 Experimental SmallMoleculeDrug DB02800 5-Hydroxymethylene-6-Hydrofolic Acid Thumb 11.7%
10 Approved;
Investigational		 SmallMoleculeDrug DB01017 Minocycline Thumb 11.2%
11 Investigational SmallMoleculeDrug DB06741 Gavestinel Thumb 11.1%
12 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00143 Glutathione Thumb 10.8%
13 Approved;
Investigational		 SmallMoleculeDrug DB09481 Magnesium carbonate Thumb 10.6%
14 Experimental;
Illicit;
Investigational		 SmallMoleculeDrug DB01520 Tenocyclidine Thumb 10.5%
15 Approved;
Nutraceutical		 SmallMoleculeDrug DB00125 L-Arginine Thumb 10.5%
16 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 10.5%
17 Approved;
Investigational		 SmallMoleculeDrug DB00996 Gabapentin Thumb 10.5%
18 Approved SmallMoleculeDrug DB06616 Bosutinib Thumb 10.4%
19 Approved SmallMoleculeDrug DB00619 Imatinib Thumb 10.3%
20 Approved;
Investigational		 SmallMoleculeDrug DB04967 Lucanthone Thumb 10.2%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.