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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P50225
No. Gene UniProt ID Protein Name Pathway PDB
1 SULT1A1 P50225 Sulfotransferase 1A1 hsa05204 1LS6; 1Z28; 2D06; 3QVU; 3QVV; 3U3J; 3U3K; 3U3M; 3U3O; 3U3R; 4GRA

2 known interactions (drugs) of input target (SULT1A1): Sulfotransferase 1A1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Experimental SmallMoleculeDrug DB04417 P-Nitrophenol Thumb
2 Experimental SmallMoleculeDrug DB01812 Adenosine-3'-5'-Diphosphate Thumb

20 predicted interactions (drugs) of input target (SULT1A1): Sulfotransferase 1A1
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB11638 Artenimol Thumb 28.1%
2 Approved SmallMoleculeDrug DB03147 Flavin adenine dinucleotide Thumb 24.0%
3 Approved;
SmallMoleculeDrug DB09130 Copper Thumb 23.6%
4 Approved;
SmallMoleculeDrug DB12010 Fostamatinib Thumb 23.4%
5 Experimental SmallMoleculeDrug DB03309 N-Cyclohexyltaurine Thumb 20.3%
6 Experimental SmallMoleculeDrug DB03277 alpha-maltotriose Thumb 20.0%
7 Approved;
SmallMoleculeDrug DB03088 Pidolic Acid Thumb 19.9%
8 Experimental SmallMoleculeDrug DB02730 4-Methylthio-Alpha-D-Mannose Thumb 17.3%
9 Experimental SmallMoleculeDrug DB02098 Adenosine-2'-5'-Diphosphate Thumb 16.2%
10 Approved;
Vet approved
SmallMoleculeDrug DB00945 Acetylsalicylic acid Thumb 15.4%
11 Experimental SmallMoleculeDrug DB01870 1,4-dithio-alpha-D-glucopyranose Thumb 14.8%
12 Experimental SmallMoleculeDrug DB02902 3'-Phosphate-Adenosine-5'-Phosphate Sulfate Thumb 14.0%
13 Experimental SmallMoleculeDrug DB07045 (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Thumb 13.9%
14 Approved;
SmallMoleculeDrug DB00313 Valproic Acid Thumb 13.9%
15 Approved;
SmallMoleculeDrug DB01708 Prasterone Thumb 13.8%
16 Experimental SmallMoleculeDrug DB02451 B-nonylglucoside Thumb 13.4%
17 Approved;
SmallMoleculeDrug DB05389 Tetrachlorodecaoxide Thumb 13.4%
18 Experimental SmallMoleculeDrug DB03092 5-Hydroxymethyl-Chonduritol Thumb 12.9%
19 Approved BiotechDrug DB00029 Anistreplase Thumb 12.8%
20 Experimental SmallMoleculeDrug DB02218 N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside Thumb 12.6%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.