QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P12104
No. Gene UniProt ID Protein Name Pathway PDB
1 FABP2 P12104 Fatty acid-binding protein, intestinal hsa03320; hsa04975 1KZW; 1KZX; 2MJI; 2MO5; 3AKM; 3IFB


2 known interactions (drugs) of input target (FABP2): Fatty acid-binding protein, intestinal
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational		 SmallMoleculeDrug DB09213 Dexibuprofen Thumb
2 Approved SmallMoleculeDrug DB01050 Ibuprofen Thumb


20 predicted interactions (drugs) of input target (FABP2): Fatty acid-binding protein, intestinal
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Approved SmallMoleculeDrug DB00795 Sulfasalazine Thumb 28.8%
2 Approved;
Vet approved		 SmallMoleculeDrug DB00945 Acetylsalicylic acid Thumb 22.1%
3 Approved SmallMoleculeDrug DB00244 Mesalazine Thumb 20.9%
4 Experimental SmallMoleculeDrug DB08848 Guvacine Thumb 20.6%
5 Approved;
Nutraceutical		 SmallMoleculeDrug DB13961 Fish oil Thumb 20.6%
6 Experimental;
Investigational		 SmallMoleculeDrug DB02587 Colforsin Thumb 19.0%
7 Approved SmallMoleculeDrug DB04941 Crofelemer Thumb 18.9%
8 Approved SmallMoleculeDrug DB08820 Ivacaftor Thumb 18.8%
9 Approved;
Investigational		 SmallMoleculeDrug DB01014 Balsalazide Thumb 18.1%
10 Approved;
Experimental;
Investigational		 SmallMoleculeDrug DB02709 Resveratrol Thumb 17.7%
11 Investigational SmallMoleculeDrug DB12340 Navitoclax Thumb 17.5%
12 Experimental SmallMoleculeDrug DB04557 Arachidonic Acid Thumb 16.8%
13 Experimental SmallMoleculeDrug DB07684 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Thumb 16.7%
14 Approved;
Investigational		 SmallMoleculeDrug DB01088 Iloprost Thumb 16.5%
15 Approved;
Investigational;
Withdrawn		 SmallMoleculeDrug DB01041 Thalidomide Thumb 16.3%
16 Approved SmallMoleculeDrug DB00573 Fenoprofen Thumb 16.3%
17 Approved SmallMoleculeDrug DB01397 Magnesium salicylate Thumb 16.2%
18 Approved;
Investigational		 SmallMoleculeDrug DB00328 Indomethacin Thumb 16.0%
19 Approved;
Investigational		 SmallMoleculeDrug DB06736 Aceclofenac Thumb 16.0%
20 Approved SmallMoleculeDrug DB06637 Dalfampridine Thumb 15.9%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.