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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P60568

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	IL2	P60568	Interleukin-2	hsa04060; hsa04151; hsa04625; hsa04630; hsa04658; hsa04659; hsa04660; hsa04672; hsa04940; hsa05142; hsa05162; hsa05166; hsa05200; hsa05320; hsa05321; hsa05330; hsa05332	1ILM; 1ILN; 1IRL; 1M47; 1M48; 1M49; 1M4A; 1M4B; 1M4C; 1NBP; 1PW6; 1PY2; 1QVN; 1Z92; 2B5I; 2ERJ; 3INK; 3QAZ; 3QB1; 4NEJ; 4NEM

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Experimental	SmallMoleculeDrug	DB03957	SP2456	[H][C@@](NC(N)=N)(C1CCCCC1)C(O)=NCC(=O)N1CCC(CC1)C1=CC(=NN1)C1=C(Cl)C(Cl)=CC=C1
2	Approved; Investigational	SmallMoleculeDrug	DB05676	Apremilast	[H][C@](CS(C)(=O)=O)(N1C(=O)C2=C(C1=O)C(=CC=C2)N=C(C)O)C1=CC(OCC)=C(OC)C=C1
3	Experimental	SmallMoleculeDrug	DB02555	SP4160	CC(C)C[C@@H](N=C(N)N)C(=O)NCC(=O)N1CCC(CC1)C1=CC(=NN1C)C1=C(Cl)C(Cl)=C(OCC2=CC=C(NC(C)=O)C=C2)C=C1
4	Approved; Investigational	BiotechDrug	DB05299	keyhole limpet hemocyanin	NA
5	Investigational	SmallMoleculeDrug	DB06083	Tapinarof	CC(C)C1=C(O)C=C(\C=C\C2=CC=CC=C2)C=C1O
6	Experimental	SmallMoleculeDrug	DB03372	3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One	SCCC(=O)N1CCC2=C(C1)NC1=C2C=CC=C1
7	Experimental	SmallMoleculeDrug	DB03455	(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid	[H][C@](NOCCS)(C(O)=O)C1=CNC2=C1C=CC=C2
8	Approved	SmallMoleculeDrug	DB00852	Pseudoephedrine	CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
9	Approved	SmallMoleculeDrug	DB01327	Cefazolin	[H][C@]12SCC(CSC3=NN=C(C)S3)=C(N1C(=O)[C@H]2NC(=O)CN1C=NN=N1)C(O)=O
10	Investigational	SmallMoleculeDrug	DB05304	WX-G250	NA
11	Experimental	SmallMoleculeDrug	DB03453	(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester	[H][C@@](CC1=CC=C(C=C1)C#CC1=CC=CC=C1)(N=C(O)C[C@@]1([H])CCCN(C1)C(N)=N)C(=O)OC
12	Experimental	SmallMoleculeDrug	DB02581	5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid	CC(C)C[C@@H](NC(N)=N)C(=O)NCC(=O)N1CCC(CC1)C1=CC(=NN1C)C1=CC=C(OCC2=CC=C(O2)C(O)=O)C(Cl)=C1Cl
13	Experimental	SmallMoleculeDrug	DB04278	2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide	[H][C@@](C)(N=C(O)CN=C(O)[C@]([H])(NC(N)=N)C1CCCCC1)C(O)=NCCCS

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved	BiotechDrug	DB10770	Foreskin fibroblast (neonatal)	NA		31.7%
2	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O		27.3%
3	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00144	Phosphatidyl serine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O		26.5%
4	Approved; Vet approved	SmallMoleculeDrug	DB08818	Hyaluronic acid	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O		23.4%
5	Approved; Investigational	SmallMoleculeDrug	DB03247	Flavin mononucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2		22.4%
6	Investigational	SmallMoleculeDrug	DB05767	Andrographolide	[H]\C(C[C@]1([H])C(=C)CC[C@]2([H])[C@](C)(CO)[C@]([H])(O)CC[C@@]12C)=C1/C(=O)OC[C@@]1([H])O		22.1%
7	Approved; Investigational	SmallMoleculeDrug	DB01136	Carvedilol	COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2		21.2%
8	Approved; Illicit	SmallMoleculeDrug	DB01576	Dextroamphetamine	C[C@H](N)CC1=CC=CC=C1		21.1%
9	Experimental	SmallMoleculeDrug	DB04464	N-Formylmethionine	[H][C@@](CCSC)(NC=O)C(O)=O		21.1%
10	Approved	SmallMoleculeDrug	DB00862	Vardenafil	CCCC1=NC(C)=C2N1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1		21.0%
11	Approved	BiotechDrug	DB11311	Prothrombin	NA		20.8%
12	Approved	SmallMoleculeDrug	DB00630	Alendronic acid	NCCCC(O)(P(O)(O)=O)P(O)(O)=O		20.7%
13	Experimental	SmallMoleculeDrug	DB08373	4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL	CS(=O)(=O)C1=CC(Cl)=C(C=C1Cl)C1=C(Cl)C=C(C(Cl)=C1)S(C)(=O)=O		20.7%
14	Experimental	SmallMoleculeDrug	DB08378	4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID	[H][C@](O)(CCC(O)=O)NC1=CC=C(C=C1)N1C(=O)CCC1=O		20.6%
15	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB01392	Yohimbine	[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2		20.5%
16	Approved	SmallMoleculeDrug	DB00540	Nortriptyline	CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12		20.4%
17	Approved; Investigational	SmallMoleculeDrug	DB01411	Pranlukast	O=C(NC1=C2OC(=CC(=O)C2=CC=C1)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1		20.3%
18	Approved; Illicit	SmallMoleculeDrug	DB01577	Methamphetamine	CN[C@@H](C)CC1=CC=CC=C1		20.1%
19	Approved; Illicit	SmallMoleculeDrug	DB01579	Phendimetrazine	C[C@H]1[C@@H](OCCN1C)C1=CC=CC=C1		19.6%
20	Approved; Investigational	BiotechDrug	DB09036	Siltuximab	NA		19.5%