QuartataWeb 1.0

15 known interactions (drugs) of input target (PLA2G2E): Group IIE secretory phospholipase A2

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Experimental	SmallMoleculeDrug	DB02636	9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid	COC1=C(O)C=CC2=C1C=C(C1=C2C2=C(OCO2)C=C1C(O)=O)[N+]([O-])=O
2	Approved	SmallMoleculeDrug	DB00233	Aminosalicylic Acid	NC1=CC(O)=C(C=C1)C(O)=O
3	Experimental	SmallMoleculeDrug	DB01955	1,4-Butanediol	OCCCCO
4	Investigational	SmallMoleculeDrug	DB04725	Licofelone	CC1(C)CN2C(CC(O)=O)=C(C(=C2C1)C1=CC=CC=C1)C1=CC=C(Cl)C=C1
5	Experimental	SmallMoleculeDrug	DB07950	1H-INDOL-3-YLACETIC ACID	OC(=O)CC1=CNC2=C1C=CC=C2
6	Experimental	SmallMoleculeDrug	DB07500	(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one	COC1=CC(O)=C(C=C1CC=C(C)C)C(=O)\C=C\C1=CC=C(O)C=C1
7	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB04743	Nimesulide	CS(=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O
8	Experimental	SmallMoleculeDrug	DB07958	(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID	CCCC1=CC2=C(NC(CC(N)=O)=C2)C(CC(O)=O)=C1
9	Experimental	SmallMoleculeDrug	DB02448	N-Tridecanoic Acid	CCCCCCCCCCCCC(O)=O
10	Experimental	SmallMoleculeDrug	DB08447	3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL	CN(C)CC1=CNC2=C1C=CC=C2CCCO
11	Experimental	SmallMoleculeDrug	DB02758	Indolylpropionic Acid	OC(=O)CCC1=CNC2=CC=CC=C12
12	Experimental	SmallMoleculeDrug	DB02795	P-Anisic Acid	COC1=CC=C(C=C1)C(O)=O
13	Experimental	SmallMoleculeDrug	DB06987	2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE	[H][C@@](O)(CNC(C)C)COC1=CC=C(CC(N)=O)C=C1
14	Approved; Investigational	SmallMoleculeDrug	DB09462	Glycerin	OCC(O)CO
15	Approved; Withdrawn	SmallMoleculeDrug	DB03585	Oxyphenbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=C(O)C=C1)C1=CC=CC=C1

20 predicted interactions (drugs) of input target (PLA2G2E): Group IIE secretory phospholipase A2

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00114	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O	35.8%
2	Approved; Investigational	SmallMoleculeDrug	DB02325	Isopropyl Alcohol	CC(C)O	33.4%
3	Experimental; Investigational	SmallMoleculeDrug	DB03496	Alvocidib	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl	30.2%
4	Experimental	SmallMoleculeDrug	DB01915	S-Hydroxycysteine	N[C@@H](CSO)C(O)=O	28.0%
5	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00167	L-Isoleucine	CC[C@H](C)[C@H](N)C(O)=O	27.2%
6	Approved; Investigational	SmallMoleculeDrug	DB00328	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O	26.6%
7	Approved	SmallMoleculeDrug	DB00363	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12	25.6%
8	Experimental	SmallMoleculeDrug	DB01692	Dithioerythritol	[H][C@](O)(CS)[C@]([H])(O)CS	25.1%
9	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB00145	Glycine	NCC(O)=O	24.7%
10	Approved	SmallMoleculeDrug	DB08439	Parecoxib	CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C1=C(C)ON=C1C1=CC=CC=C1	24.2%
11	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O	23.6%
12	Approved; Investigational	BiotechDrug	DB00052	Somatotropin	NA	23.3%
13	Approved	SmallMoleculeDrug	DB00780	Phenelzine	NNCCC1=CC=CC=C1	22.8%
14	Approved; Investigational	SmallMoleculeDrug	DB01136	Carvedilol	COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2	22.6%
15	Approved; Investigational	BiotechDrug	DB00075	Muromonab	NA	22.6%
16	Approved; Investigational; Withdrawn	SmallMoleculeDrug	DB01041	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12	22.6%
17	Approved	SmallMoleculeDrug	DB00210	Adapalene	COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2	22.2%
18	Approved; Investigational	SmallMoleculeDrug	DB04967	Lucanthone	CCN(CC)CCNC1=C2C(=O)C3=CC=CC=C3SC2=C(C)C=C1	21.9%
19	Experimental	SmallMoleculeDrug	DB03976	Phosphorylisopropane	CC(C)OP(O)(O)=O	21.8%
20	Approved; Investigational	BiotechDrug	DB00028	Immune Globulin Human	NA	20.8%