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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P00439

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	PAH	P00439	Phenylalanine-4-hydroxylase	hsa00360; hsa00400; hsa00790; hsa01100; hsa01230	1DMW; 1J8T; 1J8U; 1KW0; 1LRM; 1MMK; 1MMT; 1PAH; 1TDW; 1TG2; 2PAH; 3PAH; 4ANP; 4PAH; 5PAH; 6PAH

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Experimental	SmallMoleculeDrug	DB04419	D-norleucine	CCCC[C@@H](N)C(O)=O
2	Approved; Vet approved	SmallMoleculeDrug	DB00668	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
3	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00120	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
4	Approved	SmallMoleculeDrug	DB00368	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
5	Experimental	SmallMoleculeDrug	DB04400	L-erythro-7,8-dihydrobiopterin	[H][C@@](C)(O)[C@]([H])(O)C1=NC2=C(NC1)NC(=N)N=C2O
6	Experimental	SmallMoleculeDrug	DB02562	Quinonoid 7,8-Tetrahydrobiopterin	[H][C@@]1(CN=C2NC(N)=NC(=O)C2=N1)[C@@H](O)[C@H](C)O
7	Approved; Investigational	SmallMoleculeDrug	DB00360	Sapropterin	[H][C@@]1(CNC2=C(N1)C(=O)NC(N)=N2)[C@@H](O)[C@H](C)O
8	Approved; Investigational	SmallMoleculeDrug	DB06262	Droxidopa	N[C@@H]([C@H](O)C1=CC(O)=C(O)C=C1)C(O)=O
9	Experimental	SmallMoleculeDrug	DB03673	Beta(2-Thienyl)Alanine	N[C@@H](CC1=CC=CS1)C(O)=O

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC		44.8%
2	Approved	SmallMoleculeDrug	DB11278	DL-Methylephedrine	C[C@@H]([C@H](O)C1=CC=CC=C1)N(C)C		36.5%
3	Approved	SmallMoleculeDrug	DB04855	Dronedarone	CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2		36.2%
4	Approved	SmallMoleculeDrug	DB00925	Phenoxybenzamine	CC(COC1=CC=CC=C1)N(CCCl)CC1=CC=CC=C1		34.2%
5	Approved; Investigational	SmallMoleculeDrug	DB01064	Isoprenaline	CC(C)NCC(O)C1=CC(O)=C(O)C=C1		33.9%
6	Approved	SmallMoleculeDrug	DB01365	Mephentermine	CNC(C)(C)CC1=CC=CC=C1		33.6%
7	Approved; Investigational	SmallMoleculeDrug	DB00935	Oxymetazoline	CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C		33.5%
8	Approved; Nutraceutical; Withdrawn	SmallMoleculeDrug	DB01363	Ephedra	NA		33.3%
9	Approved; Illicit; Investigational	SmallMoleculeDrug	DB00182	Amphetamine	CC(N)CC1=CC=CC=C1		32.8%
10	Approved	SmallMoleculeDrug	DB00449	Dipivefrin	CNCC(O)C1=CC(OC(=O)C(C)(C)C)=C(OC(=O)C(C)(C)C)C=C1		32.8%
11	Approved; Investigational	SmallMoleculeDrug	DB06694	Xylometazoline	CC1=CC(=CC(C)=C1CC1=NCCN1)C(C)(C)C		32.4%
12	Investigational	SmallMoleculeDrug	DB05461	OPC-28326	O.Cl.CCC(=O)NC1=C(C)C=C(C=C1C)C(=O)N1CCC(CC1)N(C)CCC1=CC=CC=C1		32.1%
13	Approved	SmallMoleculeDrug	DB00321	Amitriptyline	CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12		31.8%
14	Approved	SmallMoleculeDrug	DB00457	Prazosin	COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1=CC=CO1		31.5%
15	Approved; Investigational	SmallMoleculeDrug	DB09229	Aranidipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OCC(C)=O		31.1%
16	Approved; Investigational	SmallMoleculeDrug	DB04846	Celiprolol	CCN(CC)C(=O)NC1=CC=C(OCC(O)CNC(C)(C)C)C(=C1)C(C)=O		30.9%
17	Approved	SmallMoleculeDrug	DB01295	Bevantolol	COC1=C(OC)C=C(CCNCC(O)COC2=CC=CC(C)=C2)C=C1		30.7%
18	Approved	SmallMoleculeDrug	DB11124	Racepinephrine	NA		30.5%
19	Approved	SmallMoleculeDrug	DB00370	Mirtazapine	CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1		30.1%
20	Investigational	SmallMoleculeDrug	DB09204	Arotinolol	CC(C)(C)NCC(O)CSC1=NC(=CS1)C1=CC=C(S1)C(N)=O		30.0%