QuartataWeb 1.0

50 known interactions (drugs) of input target (PYGM): Glycogen phosphorylase, muscle form

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Experimental	SmallMoleculeDrug	DB02471	Nojirimycine Tetrazole	[H][C@]1(O)C2=NN=NN2[C@]([H])(CO)[C@@]([H])(O)[C@]1([H])O
2	Experimental	SmallMoleculeDrug	DB03354	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole	[H][C@]1(CO)O[C@@]([H])(C2=NN=C(C)O2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
3	Experimental	SmallMoleculeDrug	DB04522	Dexfosfoserine	N[C@@H](COP(O)(O)=O)C(O)=O
4	Experimental	SmallMoleculeDrug	DB02007	alpha-D-glucose 6-phosphate	O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O
5	Experimental	SmallMoleculeDrug	DB07793	(2S)-N-[(3S)-1-(2-AMINO-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-2-CHLORO-2H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	[H][C@@]1(Cl)SC2=NC(=CC2=C1)C(=O)N[C@@]1([H])CC2=C(C=CC=C2)N(CC(N)=O)C1=O
6	Experimental	SmallMoleculeDrug	DB02719	C-(1-Hydrogyl-Beta-D-Glucopyranosyl) Formamide	[H][C@]1(O)[C@]([H])(O)[C@@]([H])(O)[C@@](O)(O[C@]1([H])CO)C(O)=N
7	Experimental	SmallMoleculeDrug	DB02348	Fluoro-Phosphite Ion	[O-]P([O-])(F)=O
8	Experimental	SmallMoleculeDrug	DB02843	alpha-D-glucose-1-phosphate	OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
9	Experimental	SmallMoleculeDrug	DB03133	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole	[H][C@]1(CO)O[C@@]([H])(C2=NC3=C(N2)C=C(C)C=C3)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
10	Experimental	SmallMoleculeDrug	DB04643	4-{3-CHLORO-4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-PHENOXY}-BUTYRIC ACID	OC(=O)CCCOC1=CC=C(NC(=O)NC(=O)C2=CC=C(Cl)C=C2Cl)C(Cl)=C1
11	Experimental	SmallMoleculeDrug	DB04195	Heptulose-2-Phosphate	C[C@]1(OP(O)(O)=O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
12	Experimental	SmallMoleculeDrug	DB08151	(5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-phenyl-1,6-dioxa-2-azaspiro[4.5]dec-2-ene-8,9,10-triol	[H][C@]1(CO)O[C@@]2(CC(=NO2)C2=CC=CC=C2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
13	Experimental	SmallMoleculeDrug	DB04295	N-Benzoyl-N'-Beta-D-Glucopyranosyl Urea	[H][C@]1(CO)O[C@@]([H])(N=C(O)N=C(O)C2=CC=CC=C2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
14	Experimental	SmallMoleculeDrug	DB03250	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole	[H][C@]1(CO)O[C@@]([H])(C2=NC3=CC(C)=CC=C3S2)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
15	Experimental	SmallMoleculeDrug	DB08500	(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol	[H][C@]1(C[C@]2(ON1)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]2([H])O)C1=CC2=CC=CC=C2C=C1
16	Experimental	SmallMoleculeDrug	DB07066	2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	[H][C@]1(CC2=C(NC1=O)C=CC=C2)NC(=O)C1=CC2=C(N1)SC(Cl)=C2
17	Experimental	SmallMoleculeDrug	DB03479	8,9,10-Trihydroxy-7-Hydroxymethyl-3-Methyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	[H][C@]1(CO)O[C@@]2(N=C(O)N(C)C2=O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
18	Experimental	SmallMoleculeDrug	DB07949	({[(3E)-2'-OXO-2',7'-DIHYDRO-2,3'-BIINDOL-3(7H)-YLIDENE]AMINO}OXY)ACETIC ACID	OC(=O)CO\N=C1/C2=CC=CCC2=N/C/1=C1\C(=O)N=C2CC=CC=C12
19	Experimental	SmallMoleculeDrug	DB03067	4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid	OC(=O)C1=C(C=C(OC2=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=C2)C=C1)C(O)=O
20	Experimental	SmallMoleculeDrug	DB07792	(S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	[H][C@@]1(CC2=C(C=CC=C2)N(CC(=O)NCCO)C1=O)NC(=O)C1=CC2=C(N1)SC(Cl)=C2
21	Experimental	SmallMoleculeDrug	DB02519	Indirubin-5-Sulphonate	OS(=O)(=O)C1=CC=C2NC(=O)\C(=C3/NC4=CC=CC=C4C3=O)C2=C1
22	Experimental	SmallMoleculeDrug	DB02379	Beta-D-Glucose	OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
23	Experimental	SmallMoleculeDrug	DB04566	Inosinic Acid	O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O
24	Experimental	SmallMoleculeDrug	DB04055	2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium	CC[N+]1=C(C)C(C(=O)OC(C)C)=C(C2=CC=CC=C2Cl)C(C(O)=O)=C1C(O)=O
25	Experimental	SmallMoleculeDrug	DB04642	7-{2,6-DICHLORO-4-[3-(2-CHLORO-BENZOYL)-UREIDO]-PHENOXY}-HEPTANOIC ACID	OC(=O)CCCCCCOC1=C(Cl)C=C(NC(=O)NC(=O)C2=CC=CC=C2Cl)C=C1Cl
26	Experimental	SmallMoleculeDrug	DB03383	5-Chloro-1h-Indole-2-Carboxylic Acid [1-(4-Fluorobenzyl)-2-(4-Hydroxypiperidin-1yl)-2-Oxoethyl]Amide	[H][C@@](CC1=CC=C(F)C=C1)(NC(=O)C1=CC2=C(N1)C=CC(Cl)=C2)C(=O)N1CCC(O)CC1
27	Experimental	SmallMoleculeDrug	DB08322	2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID	[H][C@@](CC(O)=O)(OC(=O)\C=C\C1=CC=C(O)C=C1)[C@@]([H])(OC(=O)\C=C\C1=CC=C(O)C=C1)C(O)=O
28	Experimental	SmallMoleculeDrug	DB08503	(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol	[H][C@]1(C[C@]2(ON1)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]2([H])O)C1=CC=C(C)C=C1
29	Experimental	SmallMoleculeDrug	DB02604	2-Deoxy-Glucose-6-Phosphate	O[C@H]1C[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O1
30	Experimental	SmallMoleculeDrug	DB03657	1-Deoxy-1-Methoxycarbamido-Beta-D-Glucopyranose	[H][C@]1(CO)O[C@@]([H])(N=C(O)OC)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
31	Experimental	SmallMoleculeDrug	DB02447	3,8,9,10-Tetrahydroxy-7-Hydroxymethyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	[H][C@]1(CO)O[C@@]2(N=C(O)N(O)C2=O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
32	Experimental	SmallMoleculeDrug	DB04645	5-{3-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2-METHYL-PHENOXY}-PENTANOIC ACID	CC1=C(NC(=O)NC(=O)C2=CC=C(Cl)C=C2Cl)C=CC=C1OCCCCC(O)=O
33	Experimental	SmallMoleculeDrug	DB03286	C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide	[H]C(N)(O)[C@]1(O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]1([H])O)N=[N+]=[N-]
34	Experimental	SmallMoleculeDrug	DB03218	N-Acetyl-N'-Beta-D-Glucopyranosyl Urea	[H][C@]1(CO)O[C@@]([H])(N=C(O)N=C(C)O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
35	Experimental	SmallMoleculeDrug	DB04013	1-Deoxy-1-Methoxycarbamido-Beta-D-Gluco-2-Heptulopyranosonamide	[H][C@]1(CO)O[C@](N=C(O)OC)(C(O)=N)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
36	Experimental	SmallMoleculeDrug	DB03835	N-[(5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-(hydroxymethyl)-2,4-dioxo-6-oxa-1,3-diazaspiro[4.5]dec-3-yl]acetamide	CC(=O)NN1C(=O)N[C@@]2(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C1=O
37	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00114	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
38	Experimental	SmallMoleculeDrug	DB04044	4-{2-[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid	OC(=O)C1=C(C=C(OC2=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=CC=C2)C=C1)C(O)=O
39	Experimental	SmallMoleculeDrug	DB04544	1-Deoxy-1-Acetylamino-Beta-D-Gluco-2-Heptulopyranosonamide	[H][C@]1(CO)O[C@](N=C(C)O)(C(O)=N)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
40	Experimental; Investigational	SmallMoleculeDrug	DB03496	Alvocidib	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl
41	Experimental	SmallMoleculeDrug	DB02320	1-N-Acetyl-Beta-D-Glucosamine	[H][C@]1(CO)O[C@@]([H])(N=C(C)O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
42	Experimental	SmallMoleculeDrug	DB04083	N'-Pyridoxyl-Lysine-5'-Monophosphate	[H]\C(=N/CCCC[C@]([H])(N)C(O)=O)C1=C(COP(O)(O)=O)C=NC(C)=C1O
43	Experimental	SmallMoleculeDrug	DB07807	(3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL	[H][C@@]1(O)CN(CCCC2=CC=CC=C2)C[C@]([H])(CO)[C@@]1([H])O
44	Experimental	SmallMoleculeDrug	DB02964	8,9,10-Trihydroxy-7-Hydroxymethyl-2-Thioxo-6-Oxa-1,3-Diaza-Spiro[4.5]Decan-4-One	[H][C@]1(CO)O[C@@]2(N=C(S)N=C2O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
45	Experimental	SmallMoleculeDrug	DB02720	Alpha-D-Glucopyranosyl-2-Carboxylic Acid Amide	[H][C@]1(O)[C@]([H])(O)[C@@]([H])(CO)O[C@]([H])(C(O)=N)[C@]1([H])O
46	Experimental	SmallMoleculeDrug	DB01843	3-Amino-8,9,10-Trihydroxy-7-Hydroxymethyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	[H][C@]1(CO)O[C@@]2(N=C(O)N(N)C2=O)[C@]([H])(O)[C@@]([H])(O)[C@]1([H])O
47	Experimental	SmallMoleculeDrug	DB03392	(3,4,5-Trihydroxy-6-Hydroxymethyl-Tetrahydro-Pyran-2-Yl)-Phosphoramidic Acid Dimethyl Ester	[H][C@]1(O)[C@]([H])(O)[C@@]([H])(CO)O[C@@]([H])(NP(=O)(OC)OC)[C@]1([H])O
48	Experimental	SmallMoleculeDrug	DB04644	4-{4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2,3-DIMETHYL-PHENOXY}-BUTYRIC ACID	CC1=C(C)C(OCCCC(O)=O)=CC=C1NC(=O)NC(=O)C1=CC=C(Cl)C=C1Cl
49	Experimental	SmallMoleculeDrug	DB06986	2-CHLORO-N-[(1R,2R)-1-HYDROXY-2,3-DIHYDRO-1H-INDEN-2-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	[H][C@]1(CC2=C(C=CC=C2)[C@@]1([H])O)NC(=O)C1=CC2=C(N1)SC(Cl)=C2
50	Experimental	SmallMoleculeDrug	DB01823	Beta-D-Glucopyranose Spirohydantoin	OC[C@H]1O[C@]2(NC(=O)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O

20 predicted interactions (drugs) of input target (PYGM): Glycogen phosphorylase, muscle form

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00143	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O	52.1%
2	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB04272	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O	43.6%
3	Experimental	SmallMoleculeDrug	DB03435	Uridine-5'-Diphosphate	O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O	41.9%
4	Approved; Investigational	SmallMoleculeDrug	DB09130	Copper	[Cu]	35.9%
5	Experimental	SmallMoleculeDrug	DB07396	1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid	OC(=O)C1CCN(CC1)C1=C(NC(=O)NC(=O)C2=CC(F)=C(F)C=C2Cl)C=C(F)C=C1	35.4%
6	Experimental	SmallMoleculeDrug	DB01864	5'-Guanosine-Diphosphate-Monothiophosphate	[H][C@]1(COP(O)(=O)OP(O)(=O)OP(O)(O)=S)O[C@@]([H])(N2C=NC3=C2NC(=N)N=C3O)[C@]([H])(O)[C@]1([H])O	35.1%
7	Experimental	SmallMoleculeDrug	DB03401	1D-myo-inositol 1,4,5-trisphosphate	O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O	34.7%
8	Approved	SmallMoleculeDrug	DB00200	Hydroxocobalamin	[N+]1=2[Co-3]345([N+]6=C7[C@H]([C@@](CC(=O)N)(C)[C@@]6([C@@]6(N3C(=C(C)C3=[N+]4C(C(C)(C)[C@@H]3CCC(=O)N)=CC3=[N+]5C(=C7C)[C@@](CC(=O)N)([C@@H]3CCC(=O)N)C)[C@@](C)([C@H]6CC(=O)N)CCC(NC[C@@H](C)OP(=O)(O[C@@H]3[C@H](O[C@H](N(C4=CC(=C(C=C14)C)C)C=2)[C@@H]3O)CO)[O-])=O)[H])C)CCC(=O)N)O[H]	32.9%
9	Approved	SmallMoleculeDrug	DB01050	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O	32.2%
10	Approved; Investigational	SmallMoleculeDrug	DB11638	Artenimol	[H][C@@]1(C)CC[C@@]2([H])[C@@]([H])(C)C([H])(O)O[C@]3([H])O[C@@]4(C)CC[C@]1([H])[C@@]23OO4	32.1%
11	Experimental	SmallMoleculeDrug	DB02824	N-Pyridoxyl-Glycine-5-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCC(O)=O)=C1O	32.1%
12	Approved; Investigational; Nutraceutical	SmallMoleculeDrug	DB00120	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O	32.0%
13	Approved; Nutraceutical	SmallMoleculeDrug	DB00132	Alpha-Linolenic Acid	CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O	31.1%
14	Approved; Nutraceutical	SmallMoleculeDrug	DB00126	Vitamin C	[H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO	30.7%
15	Experimental	SmallMoleculeDrug	DB04395	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O	29.9%
16	Approved; Withdrawn	SmallMoleculeDrug	DB00756	Hexachlorophene	OC1=C(CC2=C(O)C(Cl)=CC(Cl)=C2Cl)C(Cl)=C(Cl)C=C1Cl	29.2%
17	Investigational	SmallMoleculeDrug	DB05033	INCB7839	NA	29.2%
18	Experimental	SmallMoleculeDrug	DB09207	AS-8112	[H]N(C)C1=C(Br)C=C(C(=O)N([H])[C@@H]2CN(C)CCN(CC)C2)C(OC)=C1	29.2%
19	Experimental	SmallMoleculeDrug	DB02482	Phosphonothreonine	C[C@H](OP(O)(O)=O)[C@@H](N)C(O)=O	29.1%
20	Experimental	SmallMoleculeDrug	DB07838	(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE	OC1=C(\C=C2/SC(=S)N(CC3=CC=CC=C3)C2=O)C=CC=C1[N+]([O-])=O	27.8%