QuartataWeb 1.0

36 known interactions (drugs) of input target (MAOB): Amine oxidase [flavin-containing] B

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Experimental	SmallMoleculeDrug	DB08176	(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE	[H]N=C([H])C(=C)CCC1=CC=C(F)C=C1
2	Withdrawn	SmallMoleculeDrug	DB04832	Zimelidine	CN(C)CC=C(C1=CC=C(Br)C=C1)C1=CN=CC=C1
3	Approved	SmallMoleculeDrug	DB01247	Isocarboxazid	CC1=CC(=NO1)C(=O)NNCC1=CC=CC=C1
4	Approved; Investigational	SmallMoleculeDrug	DB01171	Moclobemide	ClC1=CC=C(C=C1)C(=O)NCCN1CCOCC1
5	Approved; Investigational	SmallMoleculeDrug	DB00752	Tranylcypromine	NC1CC1C1=CC=CC=C1
6	Approved; Illicit	SmallMoleculeDrug	DB00191	Phentermine	CC(C)(N)CC1=CC=CC=C1
7	Approved; Investigational	SmallMoleculeDrug	DB06654	Safinamide	C[C@H](NCC1=CC=C(OCC2=CC(F)=CC=C2)C=C1)C(N)=O
8	Approved	SmallMoleculeDrug	DB01626	Pargyline	CN(CC#C)CC1=CC=CC=C1
9	Experimental	SmallMoleculeDrug	DB08082	N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE	OCCNC(=O)C1=CC=C(Cl)C=C1
10	Experimental	SmallMoleculeDrug	DB04677	N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE	[H][C@@](C)(CC1=CC=CC=C1)N(C)CC=C
11	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00721	Procaine	CCN(CC)CCOC(=O)C1=CC=C(N)C=C1
12	Experimental	SmallMoleculeDrug	DB07512	7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE	ClC1=CC=CC(COC2=CC=C3C(OC(=O)C=C3C=O)=C2)=C1
13	Experimental	SmallMoleculeDrug	DB07513	7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE	CNCC1=CC(=O)OC2=C1C=CC(OCC1=CC=CC(Cl)=C1)=C2
14	Approved; Illicit	SmallMoleculeDrug	DB01577	Methamphetamine	CN[C@@H](C)CC1=CC=CC=C1
15	Experimental	SmallMoleculeDrug	DB02211	N-Methyl-N-Propargyl-1(R)-Aminoindan	[H][C@]1(CCC2=C1C=CC=C2)N(C)CC#C
16	Experimental	SmallMoleculeDrug	DB03894	N-Propargyl-1(S)-Aminoindan	[H][C@@]1(CCC2=C1C=CC=C2)NCC#C
17	Experimental	SmallMoleculeDrug	DB02095	Isatin	O=C1NC2=CC=CC=C2C1=O
18	Approved	SmallMoleculeDrug	DB00780	Phenelzine	NNCCC1=CC=CC=C1
19	Approved	SmallMoleculeDrug	DB03147	Flavin adenine dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
20	Experimental	SmallMoleculeDrug	DB04307	5-Hydroxy-N-Propargyl-1(R)-Aminoindan	[H][C@]1(CCC2=CC=C(O)C=C12)NCC#C
21	Withdrawn	SmallMoleculeDrug	DB04821	Nomifensine	CN1CC(C2=CC=CC=C2)C2=C(C1)C(N)=CC=C2
22	Experimental	SmallMoleculeDrug	DB04147	Lauryl Dimethylamine-N-Oxide	CCCCCCCCCCCC[N+](C)(C)[O-]
23	Approved	SmallMoleculeDrug	DB01367	Rasagiline	C#CCN[C@@H]1CCC2=CC=CC=C12
24	Experimental; Illicit	SmallMoleculeDrug	DB01442	MMDA	COC1=CC(CC(C)N)=CC2=C1OCO2
25	Approved; Investigational	SmallMoleculeDrug	DB00909	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
26	Experimental	SmallMoleculeDrug	DB08480	4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN	[H][C@]1(CCC2=C1C=CC=C2O)\N=C\C=C
27	Experimental; Illicit	SmallMoleculeDrug	DB01472	4-Methoxyamphetamine	COC1=CC=C(CC(C)N)C=C1
28	Experimental	SmallMoleculeDrug	DB02643	N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate	CCCCCCCCCCCC[N+](C)(C)CCCS(O)(=O)=O
29	Experimental	SmallMoleculeDrug	DB02509	Farnesol	CC(C)=CCC\C(C)=C/CC\C(C)=C/CO
30	Approved; Illicit; Investigational	SmallMoleculeDrug	DB00182	Amphetamine	CC(N)CC1=CC=CC=C1
31	Approved; Nutraceutical; Withdrawn	SmallMoleculeDrug	DB01363	Ephedra	NA
32	Approved; Investigational	SmallMoleculeDrug	DB01132	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
33	Withdrawn	SmallMoleculeDrug	DB04820	Nialamide	O=C(CCNNC(=O)C1=CC=NC=C1)NCC1=CC=CC=C1
34	Experimental	SmallMoleculeDrug	DB08516	(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]	[H][C@@](C)(\N=C\C1=CC=C(OCC2=CC(F)=CC=C2)C=C1)C(N)=O
35	Approved; Investigational	SmallMoleculeDrug	DB01168	Procarbazine	CNNCC1=CC=C(C=C1)C(=O)NC(C)C
36	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB01037	Selegiline	C[C@H](CC1=CC=CC=C1)N(C)CC#C

20 predicted interactions (drugs) of input target (MAOB): Amine oxidase [flavin-containing] B

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved	SmallMoleculeDrug	DB09245	Toloxatone	CC1=CC(=CC=C1)N1CC(CO)OC1=O	48.7%
2	Experimental	SmallMoleculeDrug	DB07641	Decyl(dimethyl)phosphine oxide	CCCCCCCCCCP(C)(C)=O	46.8%
3	Experimental	SmallMoleculeDrug	DB13876	Brofaromine	COC1=CC2=C(OC(=C2)C2CCNCC2)C(Br)=C1	46.8%
4	Investigational	SmallMoleculeDrug	DB04850	Posizolid	OC[C@H](O)C(=O)N1CCC(=CC1)C1=C(F)C=C(C=C1F)N1C[C@H](COC2=NOC=C2)OC1=O	44.8%
5	Approved	SmallMoleculeDrug	DB00805	Minaprine	CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1	44.6%
6	Experimental	SmallMoleculeDrug	DB07919	7-METHOXY-1-METHYL-9H-BETA-CARBOLINE	COC1=CC=C2C(NC3=C2C=CN=C3C)=C1	43.4%
7	Approved; Investigational	SmallMoleculeDrug	DB00579	Mazindol	OC1(N2CCN=C2C2=CC=CC=C12)C1=CC=C(Cl)C=C1	42.1%
8	Experimental	SmallMoleculeDrug	DB04017	Clorgiline	CN(CCCOC1=CC=C(Cl)C=C1Cl)CC#C	42.0%
9	Approved; Investigational	SmallMoleculeDrug	DB00206	Reserpine	[H][C@]12C[C@@H](OC(=O)C3=CC(OC)=C(OC)C(OC)=C3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]1([H])N(CCC3=C1NC1=C3C=CC(OC)=C1)C2	41.3%
10	Approved; Investigational	SmallMoleculeDrug	DB00313	Valproic Acid	CCCC(CCC)C(O)=O	41.3%
11	Investigational	SmallMoleculeDrug	DB05205	CX157	NA	40.7%
12	Approved	SmallMoleculeDrug	DB09244	Pirlindole	CC1=CC=C2N3CCNC4CCCC(=C34)C2=C1	40.6%
13	Approved; Illicit	SmallMoleculeDrug	DB00907	Cocaine	[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)C1=CC=CC=C1)C(=O)OC)N2C	39.0%
14	Approved; Investigational	SmallMoleculeDrug	DB06701	Dexmethylphenidate	COC(=O)[C@@H]([C@H]1CCCCN1)C1=CC=CC=C1	38.7%
15	Approved	SmallMoleculeDrug	DB01104	Sertraline	CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12	36.7%
16	Approved	SmallMoleculeDrug	DB00368	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1	35.8%
17	Approved; Investigational	SmallMoleculeDrug	DB00745	Modafinil	NC(=O)CS(=O)C(C1=CC=CC=C1)C1=CC=CC=C1	35.8%
18	Approved	SmallMoleculeDrug	DB00988	Dopamine	NCCC1=CC(O)=C(O)C=C1	35.3%
19	Approved	SmallMoleculeDrug	DB01161	Chloroprocaine	CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1	35.1%
20	Approved	SmallMoleculeDrug	DB00726	Trimipramine	CC(CN(C)C)CN1C2=CC=CC=C2CCC2=CC=CC=C12	34.3%