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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Results:

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Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: O00206

No.	Gene	UniProt ID	Protein Name	Pathway	PDB
1	TLR4	O00206	Toll-like receptor 4	hsa04064; hsa04066; hsa04145; hsa04151; hsa04217; hsa04620; hsa04621; hsa05130; hsa05132; hsa05133; hsa05134; hsa05140; hsa05142; hsa05144; hsa05145; hsa05146; hsa05152; hsa05161; hsa05162; hsa05164; hsa05170; hsa05205; hsa05321; hsa05323	2Z62; 2Z63; 2Z65; 2Z66; 3FXI; 3UL7; 3UL8; 3UL9; 3ULA; 4G8A

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image
1	Approved; Experimental	SmallMoleculeDrug	DB13615	Mifamurtide	O.[Na+].CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)[C@H](C)NC(=O)CC[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H](NC(C)=O)C=O)C(N)=O)OC(=O)CCCCCCCCCCCCCCC
2	Investigational	SmallMoleculeDrug	DB05475	Golotimod	N[C@H](CCC(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O)C(O)=O
3	Approved; Experimental	SmallMoleculeDrug	DB03017	Lauric Acid	CCCCCCCCCCCC(O)=O
4	Experimental	SmallMoleculeDrug	DB02767	3-Hydroxy-Myristic Acid	[H][C@@](O)(CCCCCCCCCCC)CC(O)=O
5	Experimental	SmallMoleculeDrug	DB08231	Myristic acid	CCCCCCCCCCCCCC(O)=O
6	Investigational	SmallMoleculeDrug	DB04933	Eritoran	[H]\C(CCCCCC)=C(/[H])CCCCCCCCCC(O)=N[C@@]1([H])[C@]([H])(OC[C@@]2([H])O[C@]([H])(OP(O)(O)=O)[C@]([H])(N=C(O)CC(=O)CCCCCCCCCCC)[C@@]([H])(OCCCCCCCCCC)[C@]2([H])O)O[C@]([H])(COC)[C@@]([H])(OP(O)(O)=O)[C@]1([H])OCC[C@@]([H])(CCCCCCC)OC
7	Approved	SmallMoleculeDrug	DB11193	Papain	NA
8	Approved; Vet approved	SmallMoleculeDrug	DB01183	Naloxone	OC1=CC=C2C[C@H]3N(CC=C)CC[C@@]45[C@@H](OC1=C24)C(=O)CC[C@@]35O

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Image	Confidence score
1	Approved; Nutraceutical; Vet approved	SmallMoleculeDrug	DB01065	Melatonin	COC1=CC2=C(NC=C2CCNC(C)=O)C=C1		29.3%
2	Approved; Nutraceutical	SmallMoleculeDrug	DB00126	Vitamin C	[H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO		27.6%
3	Investigational; Nutraceutical	SmallMoleculeDrug	DB00171	ATP	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O		24.9%
4	Experimental	SmallMoleculeDrug	DB03963	S-(Dimethylarsenic)Cysteine	[H][C@](N)(CS[As](C)C)C(O)=O		24.8%
5	Approved; Investigational	SmallMoleculeDrug	DB00295	Morphine	[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])C=C[C@@H]2O		24.3%
6	Approved; Nutraceutical	SmallMoleculeDrug	DB00157	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O		23.3%
7	Approved; Investigational	BiotechDrug	DB08870	Brentuximab vedotin	NA		21.7%
8	Approved; Investigational	BiotechDrug	DB00043	Omalizumab	NA		21.4%
9	Approved; Illicit; Investigational	SmallMoleculeDrug	DB00497	Oxycodone	[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1(O)CCC2=O		21.2%
10	Approved; Investigational	BiotechDrug	DB00028	Immune Globulin Human	NA		21.1%
11	Approved; Vet approved	SmallMoleculeDrug	DB00396	Progesterone	[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C		20.6%
12	Nutraceutical	SmallMoleculeDrug	DB00116	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1		20.2%
13	Approved; Experimental	SmallMoleculeDrug	DB03796	Palmitic Acid	CCCCCCCCCCCCCCCC(O)=O		19.9%
14	Experimental	SmallMoleculeDrug	DB03317	Heme C	CC(S)C1=C2C=C3C(C)=C(C(C)S)C4=[N+]3[Fe--]35N6C(=C4)C(C)=C(CCC(O)=O)C6=CC4=[N+]3C(=CC(N25)=C1C)C(C)=C4CCC(O)=O		18.9%
15	Approved	SmallMoleculeDrug	DB01611	Hydroxychloroquine	CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1		18.4%
16	Approved; Investigational	SmallMoleculeDrug	DB12965	Silver	[Ag]		18.3%
17	Approved	SmallMoleculeDrug	DB01431	Allylestrenol	[H][C@@]12CC[C@@](O)(CC=C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H]		18.2%
18	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1		18.0%
19	Approved; Investigational	SmallMoleculeDrug	DB03085	Glycolic acid	OCC(O)=O		17.8%
20	Experimental	SmallMoleculeDrug	DB07171	5-(2-hydroxyethyl)nonane-1,9-diol	OCCCCC(CCO)CCCCO		17.7%