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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: P62942
No. Gene UniProt ID Protein Name Pathway PDB
1 FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A NA

16 known interactions (drugs) of input target (FKBP1A): Peptidyl-prolyl cis-trans isomerase FKBP1A
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Experimental SmallMoleculeDrug DB03338 Heptyl-Beta-D-Glucopyranoside Thumb
2 Experimental SmallMoleculeDrug DB03621 L-709,587 Thumb
3 Experimental SmallMoleculeDrug DB01723 {3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid Thumb
4 Experimental SmallMoleculeDrug DB01712 (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester Thumb
5 Experimental SmallMoleculeDrug DB08231 Myristic acid Thumb
6 Experimental SmallMoleculeDrug DB02888 FKB-001 Thumb
7 Approved;
SmallMoleculeDrug DB00877 Sirolimus Thumb
8 Experimental SmallMoleculeDrug DB08597 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine Thumb
9 Experimental SmallMoleculeDrug DB04094 4-Hydroxy-2-Butanone Thumb
10 Experimental SmallMoleculeDrug DB04012 (3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine Thumb
11 Experimental SmallMoleculeDrug DB02311 Methyl Methylsulfinylmethyl Sulfide Thumb
12 Experimental SmallMoleculeDrug DB01951 Gpi-1046 Thumb
13 Approved;
SmallMoleculeDrug DB00337 Pimecrolimus Thumb
14 Approved;
SmallMoleculeDrug DB00864 Tacrolimus Thumb
15 Experimental SmallMoleculeDrug DB08520 (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE Thumb
16 Investigational SmallMoleculeDrug DB05814 GPI-1485 Thumb

20 predicted interactions (drugs) of input target (FKBP1A): Peptidyl-prolyl cis-trans isomerase FKBP1A
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Experimental SmallMoleculeDrug DB02451 B-nonylglucoside Thumb 30.8%
2 Experimental SmallMoleculeDrug DB08342 S-PALMITOYL-L-CYSTEINE Thumb 29.7%
3 Approved SmallMoleculeDrug DB01592 Iron Thumb 26.1%
4 Approved;
SmallMoleculeDrug DB00909 Zonisamide Thumb 25.9%
5 Experimental SmallMoleculeDrug DB08356 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol Thumb 25.0%
6 Approved;
SmallMoleculeDrug DB00755 Tretinoin Thumb 24.5%
7 Experimental SmallMoleculeDrug DB06982 (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid Thumb 24.4%
8 Approved SmallMoleculeDrug DB03754 Tromethamine Thumb 23.7%
9 Investigational SmallMoleculeDrug DB05241 XL765 Thumb 23.0%
10 Approved SmallMoleculeDrug DB00973 Ezetimibe Thumb 22.7%
11 Approved;
SmallMoleculeDrug DB00118 Ademetionine Thumb 22.2%
12 Experimental SmallMoleculeDrug DB04315 Guanosine-5'-Diphosphate Thumb 22.2%
13 Experimental SmallMoleculeDrug DB04137 Guanosine-5'-Triphosphate Thumb 21.7%
14 Approved SmallMoleculeDrug DB01594 Cinolazepam Thumb 21.2%
15 Experimental SmallMoleculeDrug DB07360 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea Thumb 21.1%
16 Experimental SmallMoleculeDrug DB03222 dATP Thumb 21.1%
17 Approved SmallMoleculeDrug DB00202 Succinylcholine Thumb 21.1%
18 Approved BiotechDrug DB08904 Certolizumab pegol Thumb 20.9%
19 Approved SmallMoleculeDrug DB00862 Vardenafil Thumb 20.5%
20 Approved;
BiotechDrug DB00052 Somatotropin Thumb 20.5%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.