QuartataWeb
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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q14330
No. Gene UniProt ID Protein Name Pathway PDB
1 GPR18 Q14330 N-arachidonyl glycine receptor NA NA


4 known interactions (drugs) of input target (GPR18): N-arachidonyl glycine receptor
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image
1 Approved;
Investigational		 SmallMoleculeDrug DB09061 Cannabidiol Thumb
2 Approved;
Investigational		 SmallMoleculeDrug DB14011 Nabiximols Thumb
3 Approved;
Nutraceutical;
Vet approved		 SmallMoleculeDrug DB00145 Glycine Thumb
4 Experimental;
Investigational		 BiotechDrug DB14009 Medical Cannabis Thumb


20 predicted interactions (drugs) of input target (GPR18): N-arachidonyl glycine receptor
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter		 Image Confidence score
1 Investigational SmallMoleculeDrug DB11755 Tetrahydrocannabivarin Thumb 46.1%
2 Approved SmallMoleculeDrug DB01744 Camphor Thumb 33.7%
3 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00114 Pyridoxal Phosphate Thumb 30.3%
4 Investigational SmallMoleculeDrug DB14050 Cannabidivarin Thumb 29.5%
5 Approved SmallMoleculeDrug DB00825 Menthol Thumb 29.0%
6 Investigational SmallMoleculeDrug DB05885 Seletracetam Thumb 27.9%
7 Experimental SmallMoleculeDrug DB11345 (S)-camphor Thumb 27.0%
8 Approved SmallMoleculeDrug DB09089 Trimebutine Thumb 27.0%
9 Experimental SmallMoleculeDrug DB02955 Ricinoleic Acid Thumb 26.8%
10 Approved;
Withdrawn		 SmallMoleculeDrug DB00431 Lindane Thumb 26.5%
11 Approved SmallMoleculeDrug DB00321 Amitriptyline Thumb 25.5%
12 Approved;
Vet approved		 SmallMoleculeDrug DB01221 Ketamine Thumb 25.3%
13 Approved;
Vet approved		 SmallMoleculeDrug DB00572 Atropine Thumb 24.8%
14 Approved;
Investigational		 SmallMoleculeDrug DB06155 Rimonabant Thumb 24.7%
15 Experimental SmallMoleculeDrug DB00466 Picrotoxin Thumb 24.4%
16 Approved;
Investigational		 SmallMoleculeDrug DB01593 Zinc Thumb 23.3%
17 Investigational SmallMoleculeDrug DB12695 Phenethyl Isothiocyanate Thumb 22.4%
18 Approved;
Investigational;
Nutraceutical		 SmallMoleculeDrug DB00119 Pyruvic acid Thumb 21.3%
19 Experimental;
Investigational		 SmallMoleculeDrug DB04216 Quercetin Thumb 21.3%
20 Approved;
Nutraceutical		 SmallMoleculeDrug DB00132 Alpha-Linolenic Acid Thumb 21.2%


  logl

Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.

Contact:

The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.