QuartataWeb 1.0

9 known interactions (drugs) of input target (PTGDR2): Prostaglandin D2 receptor 2

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter
1	Investigational	SmallMoleculeDrug	DB02056	Prostaglandin D2	[H][C@](O)(CCCCC)\C=C\[C@@]1([H])C(=O)C[C@]([H])(O)[C@]1([H])C\C=C/CCCC(O)=O
2	Approved; Investigational	SmallMoleculeDrug	DB00605	Sulindac	CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(C=C1)S(C)=O
3	Approved; Investigational	SmallMoleculeDrug	DB01088	Iloprost	[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C\C(C2)=C\CCCC(O)=O
4	Withdrawn	SmallMoleculeDrug	DB04828	Zomepirac	CN1C(CC(O)=O)=CC(C)=C1C(=O)C1=CC=C(Cl)C=C1
5	Approved; Investigational	SmallMoleculeDrug	DB00328	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
6	Approved; Investigational	SmallMoleculeDrug	DB00770	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
7	Approved	SmallMoleculeDrug	DB00917	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
8	Investigational	SmallMoleculeDrug	DB12789	Dinoprost	[H]\C(CCCC(O)=O)=C(/[H])C[C@@]1([H])[C@@]([H])(O)C[C@@]([H])(O)[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O)CCCCC
9	Investigational	SmallMoleculeDrug	DB13036	Ramatroban	[H][C@]1(CCC2=C(C1)C1=CC=CC=C1N2CCC(O)=O)NS(=O)(=O)C1=CC=C(F)C=C1

20 predicted interactions (drugs) of input target (PTGDR2): Prostaglandin D2 receptor 2

No.	Group	Type	Drug ID	Drug Name	SMILES ⇨ TargetHunter	Confidence score
1	Approved; Investigational	SmallMoleculeDrug	DB12010	Fostamatinib	COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC	45.7%
2	Approved; Vet approved	SmallMoleculeDrug	DB00945	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O	29.4%
3	Approved; Experimental; Investigational	SmallMoleculeDrug	DB02709	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1	29.0%
4	Approved	SmallMoleculeDrug	DB00675	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1	28.8%
5	Investigational	SmallMoleculeDrug	DB06486	Enzastaurin	CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CN(C2CCN(CC3=CC=CC=N3)CC2)C2=CC=CC=C12	26.9%
6	Approved; Investigational	SmallMoleculeDrug	DB00905	Bimatoprost	CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1	26.6%
7	Approved	SmallMoleculeDrug	DB01050	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O	25.9%
8	Approved; Investigational	SmallMoleculeDrug	DB01169	Arsenic trioxide	O=[As]O[As]=O	25.3%
9	Investigational	SmallMoleculeDrug	DB06246	Exisulind	CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(C=C1)S(C)(=O)=O	24.7%
10	Approved; Investigational	SmallMoleculeDrug	DB09211	Limaprost	CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC\C=C\C(O)=O	24.3%
11	Approved; Investigational	BiotechDrug	DB00033	Interferon gamma-1b	NA	23.8%
12	Experimental	SmallMoleculeDrug	DB02266	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F	22.8%
13	Approved	SmallMoleculeDrug	DB01656	Roflumilast	FC(F)OC1=C(OCC2CC2)C=C(C=C1)C(=O)NC1=C(Cl)C=NC=C1Cl	21.9%
14	Approved; Investigational; Vet approved	SmallMoleculeDrug	DB00477	Chlorpromazine	CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2	21.7%
15	Approved; Investigational	SmallMoleculeDrug	DB00774	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F	21.2%
16	Approved; Investigational	SmallMoleculeDrug	DB02325	Isopropyl Alcohol	CC(C)O	21.1%
17	Approved	SmallMoleculeDrug	DB00429	Carboprost Tromethamine	OCC([NH3+])(CO)CO.CCCCC[C@@](O)(C)\C=C\[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)[O-]	21.0%
18	Investigational	SmallMoleculeDrug	DB06134	SNS-314	ClC1=CC=CC(NC(=O)NC2=NC=C(CCNC3=C4SC=CC4=NC=N3)S2)=C1	20.7%
19	Approved; Investigational	SmallMoleculeDrug	DB01283	Lumiracoxib	CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(CC(O)=O)=C1	20.6%
20	Investigational	SmallMoleculeDrug	DB05147	CYT997	NA	20.2%