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Network of interactions between drugs (red spheres) and targets (blue spheres) is displayed above.
The red lines are used for the predicted interactions and the thickness of edges indicate the confidence score of predictions.

Data source: DrugBank-all; Query type: target; # of requested predictions: 20; Secondary interactions: no
Input target 1: Q16568
No. Gene UniProt ID Protein Name Pathway PDB
1 CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein NA 1HY9

1 known interactions (drugs) of input target (CARTPT): Cocaine- and amphetamine-regulated transcript protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
1 Approved;
SmallMoleculeDrug DB00182 Amphetamine Thumb

20 predicted interactions (drugs) of input target (CARTPT): Cocaine- and amphetamine-regulated transcript protein
No. Group Type Drug ID Drug Name SMILES
⇨ TargetHunter
Image Confidence score
1 Approved;
SmallMoleculeDrug DB01577 Methamphetamine Thumb 35.0%
2 Approved;
SmallMoleculeDrug DB01576 Dextroamphetamine Thumb 31.4%
3 Approved;
SmallMoleculeDrug DB01363 Ephedra Thumb 27.7%
4 Approved;
SmallMoleculeDrug DB00555 Lamotrigine Thumb 25.2%
5 Approved SmallMoleculeDrug DB00368 Norepinephrine Thumb 24.7%
6 Approved SmallMoleculeDrug DB00726 Trimipramine Thumb 24.2%
7 Approved SmallMoleculeDrug DB00370 Mirtazapine Thumb 24.1%
8 Approved;
SmallMoleculeDrug DB00865 Benzphetamine Thumb 23.9%
9 Experimental;
SmallMoleculeDrug DB01472 4-Methoxyamphetamine Thumb 23.8%
10 Approved SmallMoleculeDrug DB00540 Nortriptyline Thumb 23.8%
11 Approved SmallMoleculeDrug DB09167 Dosulepin Thumb 23.1%
12 Approved;
SmallMoleculeDrug DB04846 Celiprolol Thumb 22.9%
13 Experimental;
SmallMoleculeDrug DB01454 Midomafetamine Thumb 22.9%
14 Approved SmallMoleculeDrug DB00502 Haloperidol Thumb 22.2%
15 Withdrawn SmallMoleculeDrug DB04821 Nomifensine Thumb 21.7%
16 Investigational SmallMoleculeDrug DB05964 Amitifadine Thumb 21.7%
17 Approved SmallMoleculeDrug DB00988 Dopamine Thumb 21.6%
18 Approved SmallMoleculeDrug DB09195 Lorpiprazole Thumb 21.5%
19 Approved SmallMoleculeDrug DB00696 Ergotamine Thumb 21.5%
20 Approved SmallMoleculeDrug DB00543 Amoxapine Thumb 21.4%


Reference:  Hongchun Li, Fen Pei, D. Lansing Taylor and Ivet Bahar. (2020) QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics. Bioinformatics 36(12), 3935–3937.


The QuartataWeb server is maintained by the Bahar Lab at the Department of Computational & Systems Biology at the University of Pittsburgh, School of Medicine, and sponsored by the NIH awards P41 GM103712 and P01 DK096990; and by the Li Lab at Research Center for Computer-Aided Drug Discovery at Shenzhen Institutes of Advanced Technology, CAS.

For questions and comments please contact Hongchun Li.